Original articleRanibizumab for Diabetic Macular Edema: Results from 2 Phase III Randomized Trials: RISE and RIDE
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*Group members listed online (http://aaojournal.org).
Manuscript no. 2011-1287.
Quan Dong Nguyen and David M. Brown contributed equally to this work.
Financial Disclosure(s): The authors have made the following disclosures:
Quan Dong Nguyen – Grants to investigator's institution – Genentech, Inc., Regeneron, Pfizer; Consulting fee or honorarium – Santen Pharmaceutical Co. Ltd., Bausch & Lomb; Board membership – Genentech, Inc.; Consultancy – Santen Pharmaceutical Co. Ltd., Bausch & Lomb.
David M. Brown – Grants to investigator's institution – Genentech, Inc., Regeneron, Novartis, Alcon, Allergan, Alimera, Eli Lilly, Molecular Partners, Ophthotech, Abbott, Schering Plough, Othera Pharmaceuticals, Paloma Pharmaceuticals, Neurotech, TargeGen, Sirion Therapeutics, Inc., Jerini AG; Consulting fee or honorarium – Genentech, Inc; Support for travel to meetings – Genentech, Inc.; Consultant – Genentech, Inc., Regeneron, Allergan, Alcon, Molecular Partners, Novartis, Oraya Therapeutics, Paloma Pharmaceuticals, Steba Biotech; Speakers bureau – Genentech, Inc.
Dennis M. Marcus – Grants to investigator's institution – Allergan, Eli Lilly, Genentech, Inc., Neovista, Pfizer, Regeneron, ThromboGenics; Steering committee member – Genentech, Inc., Regeneron; Advisory board – Genentech, Inc., Regeneron; Consultant – Genentech, Inc.
David S. Boyer – Consultant – Alcon, Allergan, Eyetech, Genentech, Inc., Novartis/QLT, Neurotech, Pfizer, Regeneron; Speakers bureau – Alcon, Allergan, Genentech, Inc., Pfizer; Clinical research projects – Alcon, Allergan, Genentech, Inc., Pfizer, Regeneron.
Sunil Patel – Grants to investigator's institution – Alcon, Allergan, Alimera, Genentech, Inc., Pfizer, Ophthotech, Regeneron; Consulting fee and fees for participation in review activities or honorarium – Genentech, Inc.; Consultant – Allergan, Ophthotech; Speakers bureau – Alcon; Stock/stock options – Ophthotech.
Leonard Feiner – Consultant – Genentech, Inc.; Speakers bureau – Genentech, Inc.
Andrea Gibson – Employee – Genentech, Inc., a member of the Roche Group, and holds equity and/or options in Roche.
Judy Sy – Employee – Genentech, Inc., a member of the Roche Group, and holds equity and/or options in Roche.
Amy Chen Rundle – Employee – Genentech, Inc., a member of the Roche Group, and holds equity and/or options in Roche.
J. Jill Hopkins – Employee – Genentech, Inc., a member of the Roche Group, and holds equity and/or options in Roche.
Roman G. Rubio – Employee – Genentech, Inc., a member of the Roche Group, and holds equity and/or options in Roche.
Jason S. Ehrlich – Employee – Genentech, Inc., a member of the Roche Group, and holds equity and/or options in Roche.
Sponsored by Genentech, Inc. The sponsor worked closely with an investigator steering committee to address matters such as study design and patient recruitment and retention. The sponsor participated in design and conduct of the studies, data collection, analysis, and interpretation of results, and preparation, review, and approval of the manuscript. Support for third-party writing assistance by Ivo Stoilov, MD, CMPP of Envision Scientific Solutions was provided by Genentech, Inc.
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A list of members of the RISE and RIDE Research Group is available at http://aaojournal.org.