Original articleCorneal Higher-Order Aberrations after Descemet's Membrane Endothelial Keratoplasty
Section snippets
Patients
Thirty eyes of 30 patients (18 male, 12 female) aged 43 to 85 years (mean 68.8±9.5 years) who had undergone DMEK, 20 eyes of 20 patients (9 male, 11 female) aged 50 to 87 years (mean 69.7±10.2 years) who had undergone DSAEK, 20 eyes of 20 patients (12 male, 8 female) aged 24 to 84 years (mean 53.2±18.5 years) who had undergone PK, and 20 eyes of 20 age-matched (mean age 74.4±10.7 years) phakic controls (10 male, 10 female) consisting of patients who had undergone cataract surgery of the fellow
Results
For the final analysis of BSCVA, 8 patients (1 in the DMEK group, 5 in the DSAEK group, 1 in the PK group, and 1 in the control group) were excluded because of preexisting conditions limiting visual acuity: macular degeneration (2), diabetic cystoid macular edema (2), retinal vein occlusion with cystoid macular edema (1), amblyopia (1), and advanced glaucomatous optic atrophy (2). Patients were examined 6.5±1.2 months after DMEK, 22.6±11.8 months after DSAEK, and 103.1±74.2 months after PK.
Discussion
The advent of DMEK allows replacement of the host's diseased endothelium practically without alteration of the posterior anatomy of the cornea.7, 8, 9, 10, 11, 12 The hypothesis that ultra-thin grafts produce the best results is supported by initial experience with DMEK, with eyes exhibiting excellent visual acuity even in the early postoperative period.12, 16, 22, 23
The results of this study indicate that DMEK seems to be superior to DSAEK with respect to induced posterior corneal surface HOAs
References (39)
- et al.
Comparison of posterior lamellar keratoplasty techniques to penetrating keratoplasty
Ophthalmology
(2008) - et al.
Split cornea transplantation for 2 recipients: a new strategy to reduce corneal tissue cost and shortage
Ophthalmology
(2011) - et al.
Endothelial cell density after Descemet membrane endothelial keratoplasty: 1- to 3-year follow-up [letter]
Am J Ophthalmol
(2010) - et al.
Normal-eye Zernike coefficients and root-mean-square wavefront errors
J Cataract Refract Surg
(2006) - et al.
Optical aberrations of the human anterior cornea
J Cataract Refract Surg
(2003) - et al.
Descemet's stripping automated endothelial keratoplasty outcomes compared with penetrating keratoplasty from the Cornea Donor Study
Ophthalmology
(2010) - et al.
Making sense out of wavefront sensing
Am J Ophthalmol
(2005) - et al.
Repeatability of corneal first-surface wavefront aberrations measured with Pentacam corneal topography
J Cataract Refract Surg
(2008) - et al.
Preliminary clinical results of posterior lamellar keratoplasty through a sclerocorneal pocket incision
Ophthalmology
(2000) - et al.
Evaluation of deep lamellar endothelial keratoplasty surgery using scatterometry and wavefront analyses
Ophthalmology
(2007)
Descemet's membrane endothelial keratoplasty: prospective multicenter study of visual and refractive outcomes and endothelial survival
Ophthalmology
Six just-noticeable differences in retinal image quality in 1 line of visual acuity: towards quantification of happy versus unhappy patients with 20/20 acuity
J Cataract Refract Surg
Interaction between aberrations to improve or reduce visual performance
J Cataract Refract Surg
Posterior lamellar keratoplasty: DLEK to DSEK to DMEK
Cornea
Deep lamellar endothelial keratoplasty in the first United States patients: early clinical results
Cornea
Descemet's stripping endothelial keratoplasty
Curr Opin Ophthalmol
Descemet's stripping with endothelial keratoplasty in 50 eyes: a refractive neutral corneal transplant
J Refract Surg
Descemet-stripping automated endothelial keratoplasty
Cornea
Descemet membrane endothelial keratoplasty (DMEK) for Fuchs endothelial dystrophy: review of the first 50 consecutive cases
Eye (Lond)
Cited by (0)
Manuscript no. 2011-84.
Financial Disclosure(s): The author(s) have made the following disclosure(s): Friedrich E. Kruse is a consultant for Santen.