Original articleThe Boston Type I Keratoprosthesis: Improving Outcomes and Expanding Indications
Section snippets
Patients and Methods
A retrospective review was performed of all keratoprosthesis procedures performed by a single surgeon (AJA) between May 1, 2004, and May 31, 2008. Informed consent was obtained from each patient for the collection and analysis of preoperative and postoperative data. Study approval was granted by the institutional review board at The University of California, Los Angeles (nos. 04-11-058-01, 04-11-058-02, 04-11-058-03, and 04-11-058-04).
Demographic Features
A total of 57 Boston type 1 keratoprostheses were implanted in 50 eyes of 49 patients (1 patient underwent bilateral implantation). Twenty-five patients were male and 24 were female, with a mean patient age of 63.8 years (range, 21–95 years). Two eyes (2 patients) were excluded from the analysis of postoperative visual acuity outcomes because 1 patient died within 3 months of surgery, preventing an adequate assessment of postoperative visual recovery, and in another patient, the type I
Visual Acuity
Two-thirds or more of patients who received the Boston type I keratoprosthesis had a visual acuity of 20/20 to 20/100 at each of the specified follow-up time points. In fact, the percentage of eyes with visual acuity from 20/20 to 20/50 actually increased at each follow-up time point, from 27% at 6 months to 86% at 3 years. This is not because of the avoidance of patients with preoperative diagnoses known to be associated with a higher risk of postoperative complications for the initial cases
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Manuscript no. 2008-797.
Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.