Clinical ScienceModerate alcohol consumption is associated with advanced fibrosis in non-alcoholic fatty liver disease and shows a synergistic effect with type 2 diabetes mellitus
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Abbreviations
NAFLD
non-alcoholic fatty liver disease
NASH
non-alcoholic steatohepatitis
AUDIT
Alcohol Use Disorders Identification Test
AUDIT-C
Alcohol Use Disorders Identification Test – Consumption
PEth
phosphatidylethanol
LC-MS/MS
liquid chromatography tandem mass spectrometry
LOQ
level of quantification
T2DM
type 2 diabetes mellitus
BMI
body mass index
HOMA-IR
homeostatic model assessment for insulin resistance
ALT
alanine transaminase
AST
aspartate transaminase
INR
international normalised ratio
Keywords
Non-alcoholic fatty liver disease
Alcohol drinking
Type 2 diabetes mellitus
Phosphatidylethanol
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Senior authors contributed equally.
© 2020 The Author(s). Published by Elsevier Inc.