A prospective investigation of emotion dysregulation as a moderator of the relation between posttraumatic stress symptoms and substance use severity
Introduction
It is well-documented within the empirical literature that the experience of posttraumatic stress (PTS) symptoms (e.g., intrusive thoughts and memories, avoidance behaviors, emotional numbing, hyperarousal) following exposure to a traumatic event is associated with more severe substance use patterns (see Brady et al., 2004, Jacobsen et al., 2001). Specifically, prospective, epidemiological, and daily monitoring studies have shown that PTS symptoms are associated with increased likelihood of substance use and substance use disorders (e.g., Chilcoat and Breslau, 1998, Haller and Chassin, 2013, Kaysen et al., 2014, Leeies et al., 2010, Simpson et al., 2014). Experimental studies have also demonstrated that exposure to trauma-related reminders is associated with increased cravings for substances (Coffey et al., 2002, Saladin et al., 2003, Tull et al., 2013b) and increased attentional bias for substance-related cues (Tull, McDermott, Gratz, Coffey, & Lejuez, 2011). Furthermore, there is evidence that the severity of negative affect experienced in response to trauma-related cues is predictive of craving intensity and the level of attentional bias to substance-related cues (Tull et al., 2011, Tull et al., 2013b). Together, these findings suggest the presence of a functional relationship between PTS symptoms and substance use, such that substances may be used to alleviate either PTS symptoms themselves or the heightened emotional distress associated with the experience of PTS symptoms, consistent with both the self-medication (Khantzian, 1997, Stewart, 1996) and negative reinforcement models of substance use, respectively (Baker et al., 2004, McCarthy et al., 2010).
Yet, despite strong evidence for an association between PTS symptoms and substance use, moderators of this relation remain unclear, and little is known about the particular individuals most at-risk for problematic substance use in response to PTS symptoms. Research in this area could aid in the development of targeted prevention efforts aimed at reducing risk for the development of problematic substance use patterns among individuals experiencing PTS symptoms following exposure to a traumatic event. One particularly relevant moderating factor that may be worth investigating in this regard is emotion dysregulation. As defined here, emotion dysregulation is a multidimensional construct involving a lack of awareness and understanding of emotions, nonacceptance or avoidance of emotions, an unwillingness to experience negative emotions as part of pursuing desired goals, difficulties controlling behaviors in the face of emotional distress, and deficits in the modulation of emotional arousal, including a lack of access to effective strategies for modulating the intensity or duration of emotions (for reviews, see Gratz and Roemer, 2004, Gratz and Tull, 2010).
Studies within both nonclinical (e.g., college students, community samples) and clinical samples have consistently found that PTS symptoms are associated with greater emotion dysregulation (Bardeen et al., 2013, Ehring and Quack, 2010, McDermott et al., 2009, Tull et al., 2007, Weiss et al., 2013). In addition, numerous studies provide support for the theorized emotion regulating function of substance use among individuals experiencing symptoms of PTS. For example, Waldrop, Back, Verduin, and Brady (2007) found that substance dependent patients with (vs. without) posttraumatic stress disorder (PTSD) were more likely to use substances in response to unpleasant emotions. Further, alcohol use coping motives have been found to mediate the association between PTS symptoms and alcohol problems (Kaysen et al., 2007, Ullman et al., 2005, Yeater et al., 2010), and Bonn-Miller, Vujanovic, Boden, and Gross (2011) found that emotion dysregulation explained the association between PTS symptom severity and marijuana use coping motives. Emotion dysregulation has also been implicated in other impulsive behaviors among individuals experiencing PTS symptoms. Specifically, Weiss, Tull, Viana, Anestis, and Gratz (2012) demonstrated that emotion dysregulation accounted for the association between PTSD and engagement in a variety of impulsive behaviors within a sample of substance dependent patients. This research suggests the central role of emotion dysregulation in substance use among individuals experiencing PTS symptoms. In particular, given that the experience of PTS symptoms is associated with heightened negative emotional arousal (Orsillo, Batten, Plumb, Luterek, & Roessner, 2004), the presence of emotion dysregulation among individuals with these symptoms may increase motivation to engage in maladaptive behaviors, such as substance use, in order to quickly alleviate or escape emotional distress.
Unfortunately, one limitation of the extant research in this area is the almost exclusive reliance on cross-sectional designs, which limits conclusions regarding the temporal relations amongst PTS symptoms, emotion dysregulation, and substance use. In addition, most studies in this area have used only self-report measures of emotion dysregulation, responses to which may be influenced by an individual's willingness and/or ability to accurately report on emotional responses (Tull, Bornovalova, Patterson, Hopko, & Lejuez, 2008). Consequently, there is a need for studies in this area that utilize more objective measures of emotion dysregulation, such as laboratory-based behavioral measures. In addition to capturing in-the-moment deficits in emotion regulation, behavioral measures of emotion dysregulation are not susceptible to the same biases as self-report measures. Further, the joint use of behavioral and self-report measures of emotion dysregulation in the same study may assist in providing a more accurate and comprehensive assessment of this complex and multi-faceted construct (McHugh et al., 2011).
Thus, the goal of the present study was to examine the experience of PTS symptoms as a prospective predictor of the severity of substance use 8-months later among a sample of young adult women who had been exposed to a potentially traumatic event. Moreover, we were interested in investigating whether emotion dysregulation (assessed across both subjective and behavioral domains) moderates this association. We hypothesized that the initial experience of more severe PTS symptoms would predict more severe (i.e., frequent) substance use 8-months later, even when taking into account baseline levels of substance use severity. However, we also expected that this relationship would be moderated by emotion dysregulation, such that PTS symptom severity would predict more severe substance use 8-months later only among individuals with heightened self-reported and behaviorally indexed emotion dysregulation.
Section snippets
Participants
Participants were drawn from a large prospective study of emotion dysregulation and sexual revictimization among young adult women in the community (the population most at risk for sexual victimization; see Breslau et al., 1998, Pimlott-Kubiak and Cortina, 2003). Recruitment methods included random sampling from the community, in addition to community advertisements. With regard to random sampling, women within the targeted age range (18–25) were identified from a large database of residential
Potentially traumatic event exposure
In regard to the potentially traumatic events that were identified as most traumatic (and thus served as the basis for the PCL) by the final sample (N = 106), 20 participants (18.9%) identified an unwanted sexual experience, 23 participants (21.7%) identified exposure to a sudden unexpected or violent death, 19 participants (17.9%) identified experiencing a transportation accident, 12 participants (11.3%) identified exposure to a natural disaster, 10 participants (9.4%) identified experiencing a
Discussion
The goal of the present study was to build upon past research demonstrating an association between the experience of PTS symptoms and substance use by examining the role of emotion dysregulation in moderating this relation. Contrary to past research indicating a significant association between PTS symptoms and substance use in community, veteran, and clinical populations (e.g., Chilcoat and Breslau, 1998, Haller and Chassin, 2013, Jakupcak et al., 2010, Kaysen et al., 2014, Leeies et al., 2010,
Acknowledgements
This research was supported by National Institute of Child Health and Human Development Grant R01 HD062226, awarded to the third author (DD).
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