ReviewEosinophilic pustular folliculitis of infancy: A series of 15 cases and review of the literature
Section snippets
Methods
We performed a retrospective study of all cases of EPFI in the Hospital Niño Jesús, Madrid, Spain, between 1995 and 2011. We included only cases in which infectious processes had been ruled out and that showed tissue eosinophilia confirmed by means of smear, skin biopsy specimen, or both. We analyzed gender, age of onset, location of lesions, existence of pruritus, histologic findings, recommended treatment, duration and frequency of outbreaks, and age at resolution. We also assessed blood
Results
A total of 61 cases were evaluated, including our series of 15 cases (3 of which had previously been published in the Spanish-language literature1) and 46 more published in the literature.2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 Twelve of the previously published cases were excluded,13, 20, 21, 22, 23, 24, 25, 26, 27 some of which had already been questioned by other authors28: 1 atypical case on both clinical and histologic grounds (genital location exclusively, dermal
Discussion
EPFI is a recurrent pruriginous condition characterized by pustular lesions on the scalp and other body areas. First described in 1984 by Lucky et al,2 the scientific literature contains many case reports and a few small series of patients,2, 3, 4, 5, 7 among which ours has gathered the largest number of cases. EPFI belongs to the group of EPF, which also includes the classic EPF or Ofuji disease, typically seen in adults, and the EPF associated with immunosuppression, mainly in
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