Neutrophil cell surface receptors and their intracellular signal transduction pathways
Under a Creative Commons license
open access
Abbreviations
Abl
Abelson leukemia proto-oncogene
ADAP
adhesion and degranulation promoting adapter protein (Fyb, SLAP-130)
Asc
apoptosis-associated speck-like protein containing a CARD
BCR
B-cell receptor
C3G
Crk SH3 domain-binding guanine nucleotide exchange factor (RapGEF1)
CALDAG-GEFI
calcium and DAG-regulated guanine nucleotide exchange factor I
CARD
caspase activation and recruitment domain
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3 (CD66b)
CHO
Chinese hamster ovary cells
cIAP
cellular inhibitor of apoptosis
CLEC
C-type lectin
DAG
diacyl-glycerol
DAP12
DNAX activating protein 12
DISC
death-inducing signaling complex
Epac1
exchange protein activated by cyclic AMP 1
ERK
extracellular signal-regulated kinase
ERM
ezrin-radixin-moesin
ESL-1
E-selectin ligand 1
FADD
Fas-associated protein with death domain
FcR
Fc-receptor
FcRγ
Fc-receptor γ-chain
Fgr
Gardner–Rasheed feline sarcoma proto-oncogene
fMLP
formly-Met-Leu-Phe
GAP
GTPase activating protein
G-CSF
granulocyte colony-stimulating factor
GM-CSF
granulocyte/monocyte colony-stimulating factor
GPCR
G protein-coupled receptor
GPI
glycosylphosphatidylinositol anchor
GRK
GPCR kinase
Hck
hematopoietic cell kinase
ICAM-1
intercellular adhesion molecule 1
IFN
interferon
IKK
IκB kinase
IL
interleukin
IP3
inositol-tris-phosphate
IRAK
IL-1 receptor-associated kinase
IRF
IFN regulatory factor
ITAM
immunoreceptor tyrosine-based activation motif
IκB
inhibitor of NF-κB
JAK
Janus kinase
JNK
c-Jun N-terminal kinase
LAD
leukocyte adhesion deficiency
LFA-1
lymphocyte function-associated receptor 1 (αLβ2 integrin)
LTβ
lymphotoxin β
LTB4
leukotriene B4
Mac-1
macrophage antigen 1 (αMβ2 integrin)
MAP kinase
mitogen-activated protein kinase
MAPKAP-kinase
MAP kinase-associated protein kinase
Mcl
macrophage C-type lectin
MDA5
melanoma differentiation-associated protein 5
MDL-1
myeloid DAP12-associating lectin 1
MIP
macrophage inflammatory protein
MKK
MAP kinase kinase
MyD88
myeloid differentiation protein 88
NF-κB
nuclear factor κB
NLRP3
NOD-like receptor family, pyrin domain containing 3
NOD
nucleotide-binding oligomerization domain containing protein
OSCAR
osteoclast-associated receptor
PAF
platelet activating factor
PAK
p21-activated kinase
PI3K
phoshoinositide-3-kinase
PIP3
phosphatidylinositol-3-phosphate
PIR
paired immunoglobulin-like receptor
PKB
protein kinase B
PKC
protein kinase C
PLC
phospholipase C
PSGL-1
P-selectin glycoprotein ligand
Rac
Ras-related C3 botulinum toxin substrate
RANK
receptor activator of NF-κB
Rap
Ras-related protein
RIG
retinoic acid-inducible gene
RIP3
receptor-interacting serine-threonine protein kinase 3
ROS
reactive oxygen species
SAP130
Sin3A-associated protein of 130 kDa
SH2
Src-homology 2 domain
SHP-1
SH2 domain-containing protein tyrosine phosphatase 1
SLP-76
SH2 domain-containing leukocyte protein of 76 kDa
SOCS
suppressor of cytokine signaling
Src
Rous sarcoma virus proto-oncogene
STAT
signal transducer and activator of transcription
Syk
spleen tyrosine kinase
TAK
TGFβ-activated kinase 1
TCR
T-cell receptor
TGFβ
transforming growth factor β
TLR
Toll-like receptor
TNF
tumor necrosis factor
TRADD
TNFR1-associated death domain protein
TRAF
TNF receptor-associated factor
TRAIL
TNF-related apoptosis-inducing ligand
TREM
triggering receptor expressed on myeloid cells
Tyk2
tyrosine protein kinase 2
VASP
vasodilator-stimulated phosphoprotein
VCAM-1
vascular cell adhesion molecule 1
VLA-4
very late antigen 4 (α4β1 integrin)
ZAP-70
ζ-chain-associated protein of 70 kDa
Keywords
Neutrophils
Signaling
Receptors
Kinases
Inflammation
Cited by (0)
Copyright © 2013 The Authors. Published by Elsevier B.V.