Brief CorrespondencePredictors of Cancer-specific Mortality After Disease Recurrence in Patients with Squamous Cell Carcinoma of the Penis
References (9)
- et al.
EAU penile cancer guidelines 2009
Eur Urol
(2010) - et al.
Population-based survival of penile cancer patients in Europe and the United States of America: no improvement since 1990
Eur J Cancer
(2013) - et al.
Recurrence patterns of squamous cell carcinoma of the penis: recommendations for follow-up based on a two-centre analysis of 700 patients
Eur Urol
(2008) - et al.
Recurrence interval affects survival after local relapse of oral cancer
Oral Oncol
(2009)
Cited by (11)
Management of Advanced Penile Cancer
2021, Mayo Clinic ProceedingsCitation Excerpt :A review of the currently available systemic chemotherapy regimens is summarized in Table 1.40,41–43,44 Unfortunately, there are currently no clinical or pathologic factors that can accurately predict a patient’s benefit from neoadjuvant chemotherapy.49–51 The only strong predictor of better survival after neoadjuvant chemotherapy is achievement of a pCR at the time of consolidative surgical treatment.41
Survival outcomes of organ sparing surgery, partial penectomy, and total penectomy in pathological T1/T2 penile cancer: Report from the National Cancer Data Base
2018, Urologic Oncology: Seminars and Original InvestigationsCitation Excerpt :TP has a low recurrence rate in early stage PC. However the psychological and functional outcomes of the procedure are devastating [8]. PP is associated with a low recurrence rate in early stage PC [9,10].
Epidermal growth factor receptor as an adverse survival predictor in squamous cell carcinoma of the penis
2017, Human PathologyCitation Excerpt :Intriguingly, although FISH alterations represented an independent risk factor for death from cancer, they were not associated with recognized clinical and pathological variables of unfavorable outcome, with the exception of histologic grade, as only 1 low-grade tumor presented FISH alterations. High histologic grade has been described extensively as a variable forecasting a poor prognosis in PC [1,2,11,12], as have lymph node involvement and perineural invasion [3,4,11,37]. Nearly half (14 of 31) of the cases without FISH alterations were clinically N1 or N2; 7 of them also had pathologically confirmed lymph node involvement, but the patients did not die of the disease.
Epithelial-mesenchymal transition (EMT) phenotype at invasion front of squamous cell carcinoma of the penis influences oncological outcomes
2016, Urologic Oncology: Seminars and Original InvestigationsCitation Excerpt :Clinical stage, histological subtype and grade, pattern of invasion, perineural/vascular invasion, and lymph node metastasis are the most important prognostic factors in PC. But, these parameters are difficult to apply to small biopsies, because PC is heterogeneous, especially when it invades preputial lamina propria or corpus spongiosum/cavernosum [2,3,7,11]. The identification of new molecular prognostic markers can assist in managing this group of patients and possibly avoid aggressive treatments, such as extended lymphadenectomy (Table 4).
Clinical and Novel Biomarkers in Penile Carcinoma: A Prospective Review
2022, Journal of Personalized Medicine
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Both authors contributed equally to this manuscript.