Clinical ResearchUsefulness of Neutrophil-to-Lymphocyte Ratio to Predict In-hospital Outcomes in Infective Endocarditis
Section snippets
Methods
We retrospectively analyzed clinical, laboratory, and echocardiographic data from a total of 122 consecutive adult patients with definite IE between January 2009 and December 2011 at Turkey Yuksek Ihtisas Educational and Research Hospital (Ankara, Turkey). All patients met the modified Duke criteria18 for the definitive diagnosis of IE. One patient was excluded from the study because of unexplained pancytopenia, thus leaving 121 patients to analyze.
Each participant underwent a comprehensive
Results
A total of 121 patients (64 men; mean age, 54.7 ± 14.2 years; range, 21-78 years) with a definitive diagnosis of IE were analyzed. Patients were assigned to 2 groups according to the presence of prespecified clinical outcomes. Among all patients, the prespecified clinical outcomes were experienced by 46 patients (38%). In-hospital mortality occurred in 29 patients (24%) and clinically overt CNS events in 21 patients (17%). The composite clinical outcomes and details of CNS events are presented
Discussion
In the present study, we investigated the accuracy of the neutrophil-to-lymphocyte ratio at admission for predicting in-hospital prognosis in participants with definite IE. At least 1 unfavourable outcome was identified during hospitalization in 38% of the study population. The neutrophil-to-lymphocyte ratio at admission was calculated to be significantly higher for either composite end points—namely, mortality and CNS events—during hospitalization (Fig. 3). High neutrophil-to-lymphocyte ratio
Disclosures
The authors have no conflicts of interest to disclose.
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2020, Journal of Cardiothoracic and Vascular AnesthesiaThe utility of peripheral blood leucocyte ratios as biomarkers in infectious diseases: A systematic review and meta-analysis
2019, Journal of InfectionCitation Excerpt :The initial mean FGSI did not differ between groups. In a case control study of patients with infective endocarditis diagnosed using the modified Duke Criteria,49 NLR was examined as a predictor of adverse in-hospital outcomes.50 These were defined as in-hospital mortality or an intra-cerebral event (cerebrovascular event, meningitis, embolism, or brain haemorrhage).
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