Original articleGeneral thoracicPulmonary Resection for Metastases of Colorectal Adenocarcinoma
Section snippets
Patients and Methods
The records of 127 consecutive patients who underwent pulmonary resection for metastases of colorectal adenocarcinomas between 1985 and 2007 at Georges Pompidou European Hospital, Paris, and Cedar Surgical Centre, Bois-Guillaume, were reviewed. Both institutional review boards waived obtaining patient consent for this retrospective study. Preoperative selection criteria were as follows: completely resectable lesions, no evidence of synchronous extrathoracic metastasis, and controlled primary
Results
There were 74 men and 53 women. The median age was 65 years (range, 36 to 85 years). The primary tumor was located in the rectum in 61 patients (47.3%) and in the colon in 52 patients (40.3%), and the precise location was not available in 14 (“colorectal” carcinomas, 12.4%). The mean interval between colon and lung surgery was 37.8 months (±21.5 months), and the median was 36 months (range, 1 to 134 months). Lung metastases were diagnosed during colorectal cancer workup (synchronous metastases)
Comment
The first case series of resection for pulmonary metastases was published in 1947 [5]. Thirty years later, at the end of the 1970s, more generous indication for lung metastases was advocated [6, 7]. In 1997, the International Registry of Lung Metastases was established and reported on 5,206 patients who underwent metastasectomy [8]. Bowel metastases represented the most important cohort, accounting for 12.4% of the patients (n = 645). When considering colorectal cancer, approximately 10% of all
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