Elsevier

The Annals of Thoracic Surgery

Volume 88, Issue 6, December 2009, Pages 1923-1931
The Annals of Thoracic Surgery

Original article
Pediatric cardiac
Recurrent Coarctation: Is Surgical Repair of Recurrent Coarctation of the Aorta Safe and Effective?

Presented at the Forty-fourth Annual Meeting of The Society of Thoracic Surgeons, Fort Lauderdale, FL, Jan 28–30, 2008.
https://doi.org/10.1016/j.athoracsur.2009.07.024Get rights and content

Background

Persistence or recurrence of stenosis is a complication of coarctation repair and is associated with major long-term morbidity. The rate of recurrence varies significantly, depending on the age of the patient, technique at initial repair, and the arch anatomy. We reviewed our experience with surgical repair of recurrent coarctation of the aorta and compared it with our institutional experience with balloon aortoplasty.

Methods

We retrospectively reviewed our experience with 1,012 patients undergoing initial repair of coarctation between 1960 and 2008. During that time, 103 patients (10%) required reintervention. Median age at reintervention was 6.5 years (range, 2 weeks to 44 years) and median weight was 12 kg (range, 1.9 to 94 kg). Fifty-nine patients with recoarctation had surgical repair, and 44 patients were treated with balloon aortoplasty with or without stent placement.

Results

Ninety-five percent of patients have been followed up (median time, 14.2 years; range, 2 months to 42 years). There were 5 late deaths. Actuarial survival was 98% at 15 and 40 years in patients with surgical reintervention, and it was 91% (p = 0.001) at 15 years in patients with balloon aortoplasty reintervention. A second redo coarctation of the aorta reintervention was performed in 12 patients: 8 patients after percutaneous intervention (nonsurgical) and 4 patients after surgical recoarctation repair. The median interval between first and second reintervention was 3.5 years (range, 1 month to 14 years). One patient who had two dilations underwent a third and fourth reintervention: patch enlargement and pseudoaneurysm resection. Freedom from reintervention in the surgical group was 96% at 15 years and 94% at 40 years, which was compared with actuarial freedom from reintervention for patients with percutaneous intervention (balloon/stent) at 15 years (82%; p < 0.001).

Conclusions

Our study demonstrates that surgical repair of recurrent coarctation of the aorta can be performed safely and with excellent results. The recurrence after surgical reintervention is low, and most patients to date have not required further intervention. Balloon aortoplasty as an alternative method of managing recoarctation is efficient and less invasive than surgery; however, well-described complications may occur. Recurrence rates with angioplasty are significantly higher than with surgery.

Section snippets

Material and Methods

This study was approved by the Institutional Review Board at Indiana University. The need for individual consent was waived.

Results

One hundred and three patients have presented with recurrent or persistent CoA after an initial repair. There were 54 boys and 49 girls. Median age at reintervention was 6.5 years (range, 2 weeks to 44 years), and median weight was 12 kg (range, 1.9 to 94 kg). Details concerning of their initial aortic repair techniques are outlined in Table 2. Median age at primary repair was 27 days (range, 3 days to 20 years), and median interval from primary repair to reintervention for recurrent aortic

Comment

During the past 45 years, 103 patients presented with recurrent CoA after a primary repair. As in other centers [5, 7], the recurrent rate represents 10% of the patient population treated with surgery. Risk factors for this complication are initial repair at less than 1 month of age and the size and anatomy of the transverse arch [6, 9, 10, 16]. Dodge-Khatami and colleagues [6], in a 40-year meta-analysis review, showed that simple end-to-end anastomosis and subclavian flap repair had the

References (26)

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