MiscellaneousNational Trends in Pulmonary Embolism Hospitalization Rates and Outcomes for Adults Aged ≥65 Years in the United States (1999 to 2010)
Section snippets
Methods
We identified 100% of Medicare fee-for-service beneficiaries (≥65 years) using 1999 to 2010 inpatient claims data from the Centers for Medicare and Medicaid Services (CMS) who had participated for at least 1 month in fee-for-service and resided and were hospitalized for PE from January 1, 1999 to December 31, 2010, in the United States. Hospitalizations for PE were defined as discharged from an acute-care hospital for a principal discharge diagnosis of PE according to the following the
Results
We identified 380,427,267 beneficiary records, representing 80,248,916 unique beneficiaries aged ≥65 years from 1999 to 2010 of which 545,243 were hospitalized for PE from January 1, 1999, and December 31, 2010. Detailed characteristics of patients hospitalized for PE are reported in Table 1.
The crude hospitalization rate for PE was 129 per 100,000 person-years in 1999, and after adjusting for age, gender, and race, the overall hospitalization rate gradually increased to 302 per 100,000
Discussion
To our knowledge, this is the largest study to date that examined the recent trends in PE hospitalization rates and outcomes across the United States in older adults. From 1999 to 2010, we found a substantial increase in the hospitalization rates for PE and concomitant decline in inhospital and risk-adjusted 30-day and 6-month mortality rates, length of stay, proportion of patients discharged to home, and stable risk-adjusted 30-day readmission rates for Medicare beneficiaries. Although the
Acknowledgment
The contents of the report are solely the responsibility of the authors and do not necessarily represent the official view of NIH.
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Funding: This was supported by grant number U01 HL105270-05 from the National Heart, Lung, and Blood Institute at the National Institutes of Health.
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