ReviewObstetricsPaternal factors and low birthweight, preterm, and small for gestational age births: a systematic review
Section snippets
Materials and Methods
The data were extracted from published articles; therefore, no ethical approval was obtained.
Description of studies
Thirty-eight studies were included in this review.5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42 Some of the included studies reported on >1 paternal factor. Paternal alcohol use was identified as an exposure during the literature review (which was not planned a priori). Eleven studies were excluded after detailed evaluation. Details of included studies and reasons for excluded studies are given
Comment
In this systematic review of 36 studies on paternal factors and birth outcomes, certain positive and negative associations were observed. Extreme paternal ages (<20 and >40 years) may be associated with LBW; however, no consistent associations with PTBs and SGA births were identified. Paternal height and paternal occupational exposure to lead were associated with LBW and birthweight of the offspring. The infant's birthweight increased with a higher paternal birthweight. Paternal weight, body
Acknowledgments
We sincerely thank Elizabeth Uleryk, Chief Librarian at the Hospital for Sick Children, Toronto, for her contribution in developing search strategy and running searches on a periodic basis, for which she did not receive any compensation. Contributors: guarantor: Shah PS; grant concept and design: all members of the group; study concept and design: Shah PS; acquisition of data, analysis, and interpretation of data, drafting of the manuscript: Shah PS; critical revision of the manuscript for
References (64)
- et al.
Chemical and physical exposures of parents: effects on human reproduction and offspring
Early Hum Dev
(1978) - et al.
Intrauterine growth retardation as an endpoint in mutation epidemiology: an evaluation based on paternal age
Mutat Res
(1995) - et al.
Father's effect on infant birth weight
Am J Obstet Gynecol
(1998) - et al.
Low birthweight and preterm delivery, Scotland, 1981-84: effect of parents' occupation
Lancet
(1991) - et al.
Semen characteristics as a function of age in 833 fertile men
Fertil Steril
(1983) - et al.
Reproductive ability and progeny of F 1 lead-toxic rats
Fertil Steril
(1971) - et al.
Paternal age and congenital malformations
Hum Reprod
(2005) - et al.
Paternal age over 40 years: the “amber light” in the reproductive life of men?
J Androl
(2003) - et al.
Intergenerational influences, paternal factors and fetal factors
- et al.
Effects of maternal and paternal age on Caucasian and Native American preterm births and birth weights
Am J Perinatol
(2002)
Paternal age and preterm birth in Italy, 1990 to 1998
Epidemiology
Paternal age and delivery before 32 weeks
Epidemiology
Paternal age and adverse birth outcomes: teenager or 40+, who is at risk?
Hum Reprod
Relationship of paternal factors to birth weight
J Reprod Med
Paternal age as a risk factor for low birthweight
Am J Public Health
The relationship between parental age and birth order with the percentage of low birth-weight infants
Hum Biol
Is paternal age associated with an increased risk of low birthweight, preterm delivery, and multiple birth?
Can J Public Health
Paternal age and preterm birth
Epidemiology
Parental stature and birth weight
Am J Hum Genet
Parental determinants of birth weight
Clin Genet
Effect of parental anthropometric parameters on neonatal birth weight and birth length
Coll Antropol
The influence of paternal height and weight on birth-weight
Aust N Z J Obstet Gynaecol
Birthweight and paternal height
BJOG
Paternal height and weight as determinants of birth weight in a Chinese population
Am J Perinatol
Paternal influences on birthweight
Acta Obstet Gynecol Scand
Anthropometric determinants of birth weight
Obstet Gynecol
Relation of parental birth weights to infant birth weight among African Americans and whites in Illinois: a transgenerational study
Am J Epidemiol
Paternal and maternal birthweights and the risk of infant preterm birth
Am J Obstet Gynecol
Mother's and father's birthweight as predictors of infant birthweight
Paediatr Perinat Epidemiol
Paternal contribution to birth weight
J Epidemiol Community Health
Reproductive effects of paternal exposure to chlorophenate wood preservatives in the sawmill industry
Scand J Work Environ Health
Adverse reproductive outcomes among male painters with occupational exposure to organic solvents
Occup Environ Med
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This study was supported by funding from the Canadian Institute of Health Research (CIHR) Knowledge Synthesis/Translation Grant no. KRS 86242. The CIHR has played no role in the analyses, the writing of the report, the interpretation of data, or the decision to submit the manuscript.