Original articleMorphologic Characteristics of Optic Nerve Head Drusen on Spectral-Domain Optical Coherence Tomography
Section snippets
Methods
This study was approved by the Institutional Review Board of Seoul National University Bundang Hospital and adhered to the tenets of Declaration of Helsinki. This study was designed as a retrospective case series. Sixty-one patients with optic nerve head drusen seen at our institution from September 2009 through May 2012 were included in this study. All patients underwent a full ophthalmologic examination initially, including measurement of best-corrected visual acuity, funduscopic examination
General Characteristics and Classification of Optic Nerve Head Drusen
Optic nerve head drusen were identified in 99 eyes from 61 patients and were not found in the other 23 eyes. Among this group, 44 patients (72%) were women and 38 patients (62%) had bilateral optic nerve head drusen. Optic nerve head drusen were visible in 4 eyes from 3 patients by funduscopic examination (Figure 2), whereas buried optic nerve head drusen were detected in 95 eyes from 58 patients with SD OCT (Figure 1; Table 1). Ninety-five eyes with buried optic nerve head drusen were
Discussion
This study presents the detailed SD OCT features of optic nerve head drusen, which were used to classify optic nerve head drusen subtypes (visible or buried; small, medium, or large). On SD OCT images, visible optic nerve head drusen contained heterogeneous materials presented as multiple internal cysts with hyperreflective walls, suggestive of calcification. Buried optic nerve head drusen exhibited a broad spectrum of internal homogeneity and lobulations according to size. The differences
Kyoung Min Lee, MD, received his medical degree from Seoul National University in 2006, and completed a medical internship and a residency in ophthalmology at Seoul National University Hospital in 2011. He currently performs his military duties at Aerospace Medical Center, South Korea Air Force.
References (20)
- et al.
The rate of visual field loss in optic nerve head drusen
Am J Ophthalmol
(2005) - et al.
Differentiation of optic nerve head drusen and optic disc edema with spectral-domain optical coherence tomography
Ophthalmology
(2011) - et al.
Disc drusen
Ophthalmology
(2012) - et al.
Disc drusen. Author reply
Ophthalmology
(2012) Pathology and pathogenesis of drusen of the optic nerve head
Ophthalmology
(1981)- et al.
Optic disk drusen
Surv Ophthalmol
(2002) - et al.
Visual field defects and retinal nerve fiber layer defects in eyes with buried optic nerve drusen
Am J Ophthalmol
(2006) - et al.
Visual manifestations of visible and buried optic disc drusen
J Neuroophthalmol
(2004) - et al.
A comparison of imaging techniques for diagnosing drusen of the optic nerve head
Arch Ophthalmol
(1999) - et al.
Differentiating optic disc edema from optic nerve head drusen on optical coherence tomography
Arch Ophthalmol
(2009)
Cited by (64)
Reply to Comment on: Morphologic Features of Buried Optic Disc Drusen on En Face Optical Coherence Tomography and Optical Coherence Tomography Angiography
2020, American Journal of OphthalmologyComment on: Morphologic Features of Buried Optic Disc Drusen on En Face Optical Coherence Tomography and Optical Coherence Tomography Angiography
2020, American Journal of OphthalmologyMorphologic Features of Buried Optic Disc Drusen on En Face Optical Coherence Tomography and Optical Coherence Tomography Angiography
2020, American Journal of OphthalmologyCitation Excerpt :Compared to other imaging modalities, en face OCT offers supreme visualization of buried ODD in both 2- and 3-dimensional images. In our previous study, the halo sign (defined as the presence of a bright-colored, smooth-contoured strip between the nasal disc margin and the juxtapapillary retina) on fundus photography and subretinal hyperreflective mass on SDOCT strongly favored a diagnosis of buried ODD rather than ODE.12,17 The en face OCT features in the current study correspond to those previously observed using other imaging modalities.
Peripapillary hyperreflective ovoid mass-like structures and the retinal nerve fiber layer thinning
2024, European Journal of Ophthalmology
Kyoung Min Lee, MD, received his medical degree from Seoul National University in 2006, and completed a medical internship and a residency in ophthalmology at Seoul National University Hospital in 2011. He currently performs his military duties at Aerospace Medical Center, South Korea Air Force.