Original articleOcular Signs Predictive of Tubercular Uveitis
Section snippets
Methods
We conducted a retrospective chart analysis of all consecutive uveitis patients attending the uveitis clinic of our institution between 1991 and 2005. Institutional ethics committee approval was obtained. We compared clinical signs between 2 groups of patients. Group A included patients with a diagnosis of presumed TB uveitis. Group B, which served as the control group, included patients with uveitis presumed to be of nontubercular origin. Patients with the following inclusion criteria were
Results
There were 182 patients in group A, with 95 males and 87 females. Group B had 204 patients, with 101 males and 103 females. During the same period, an additional 134 patients were diagnosed with presumed TB uveitis but were not included in group A, because they did not fulfill the inclusion criteria, that is, less than 1 year of follow-up (92 patients), intolerance or adverse side effects to antitubercular therapy (14 patients), and poor compliance (28 patients). Likewise, 74 patients with
Discussion
Uveal involvement in TB has been recognized for a long time. Choroidal tubercles, identical to tubercles elsewhere in the body, were one of the earliest signs described in miliary TB.8 Over the years, the clinical spectrum of tubercular uveitis has widened and includes anterior uveitis typically presenting as granulomatous uveitis with or without iris nodules or uncommonly as nongranulomatous inflammation, intermediate uveitis, ciliary body tuberculoma, and posterior uveitis commonly in the
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