Randomized bilateral comparison of excimer laser in situ keratomileusis and photorefractive keratectomy for 2.50 to 8.00 diopters of myopia
Section snippets
Patient population
Thirty-three patients with myopia (66 eyes) were enrolled in the study between October 1993 and March 1994. Each patient received LASIK in one eye (LASIK group) and PRK in the other eye (PRK group) during the same surgical session by the same surgeon using the same laser and microkeratome in the outpatient surgery center of the El-Maghraby Eye Hospital, Jeddah, Saudi Arabia. The order of the two laser procedures and the eye treated were first randomized using a random number table.
Inclusion
Patient population
There were 22 male and 11 female patients ranging in age from 16 to 59 years (mean, standard deviation, 26.2 ± 9.3 years). The baseline spherical equivalent of the manifest refraction ranged from −2.30 to −8.10 D (mean, −4.80 ± 1.60 D in LASIK-treated eyes and −4.70 ± 1.50 D in PRK-treated eyes). Mean baseline refractive cylinder power was 0.50 ± 0.40 D (range, 0–1.75 D) in LASIK-treated eyes and 0.40 ± 0.40 D (range, 0–1.50 D) in PRK-treated eyes. Mean baseline keratometric power was 43.7 ±
Study design
This trial controlled numerous variables by having the same surgeon use the same equipment on two eyes of the same patient during the same surgical session to compare two different procedures: LASIK and PRK. Such a design minimized variability in laser performance, since the laser was calibrated and room conditions were consistent during the approximately 20 minutes required to treat both eyes. The order of the procedures and the order of the eyes for treatment were randomized to decrease any
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