Glaucoma associated with keratoprosthesis1☆,
Section snippets
Methods
Patients treated with keratoprosthesis and glaucoma drainage implant gave verbal consent and signed an informed consent form approved by the Institutional Review Board. Eyes with keratoprostheses were from a consecutive series of cases performed from March 1990 to June 1996. No eyes with keratoprosthesis implanted during this period were excluded from the analysis. Glaucoma drainage implants were performed in eyes with keratoprosthesis from February 1991 to June 1996. The surgical procedures
Results
The characteristics of the patients are listed in Table 1. A total of 55 keratoprostheses were implanted in 52 patients. The mean ± standard deviation age was 64 ± 19 years, with a range of 24 to 93 years. The follow-up period was 21 ± 16 months, with a range of 3 to 77 months. Glaucoma drainage devices were implanted in 36 eyes (65% of total) in 34 patients (65% of total). The type of keratoprosthesis was significantly different in the patients with and without glaucoma drainage implants (P =
Discussion
Keratoprosthesis may be the only option for visual rehabilitation of certain patients with severe ocular surface disease, including those with ocular cicatricial pemphigoid, Stevens-Johnson syndrome, end-stage dry eye, severe chemical burns, and repeated failure of penetrating keratoplasty. However, these patients may have a high incidence of glaucoma even before keratoprosthesis implantation. In a series of 111 patients (none with keratoprosthesis) with ocular cicatricial pemphigoid, 29
Acknowledgements
The authors thank Dr. C. Stephen Foster for patient referrals.
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Supported by Mr. Sa’ad A. A. Al-Rashed, Kuwait.
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The authors have no propriety interest in the devices used in this study.