Elsevier

Ophthalmology

Volume 87, Issue 10, October 1980, Pages 1044-1049
Ophthalmology

Botulinum Toxin Injection into Extraocular Muscles as an Alternative to Strabismus Surgery

https://doi.org/10.1016/S0161-6420(80)35127-0Get rights and content

Abstract

Sixty-seven injections of botulinum A toxin were given to patients for correction of strabismus. No systemic complications of any kind have occurred. The maximum time of paralysis occurs four to five days following the injection, and then gradually diminishes, depending on the dose. The maximum correction of strabismus has been 40 prism diopters. The maximum follow-up following injection is six months. Injection of botulinum A toxin into extraocular muscle to weaken the muscle appears to be a practical adjunct or alternative to surgical correction.

References (3)

  • AB Scott et al.

    Pharmacologic weakening of extraocular muscles

    Invest Ophthalmol

    (1973)
There are more references available in the full text version of this article.

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Presented at the Eighty-Fourth Annual Meeting of the American Academy of Ophthalmology, San Francisco, November 5–9, 1979.

Supported by grants 5P30 EY 01186 and 5R01 EY 02106 from the National Institutes of Health, and by the Smith-Kettlewell Eye Research Foundation.

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