Ocular hemodynamics in pseudoexfoliation syndrome and pseudoexfoliation glaucoma
Section snippets
Materials and methods
Forty-two patients taken into the study were monitored and treated in the Ophthalmology Department and Glaucoma Unit of the Medical Faculty of Kocaeli University. Of those, 14 patients had pseudoexfoliation glaucoma, 14 had pseudoexfoliation syndrome; 14 had no ocular pathologic features other than refractive errors and had intraocular pressure less than 21 mmHg were included as controls. Written informed consent was obtained from each participant before study initiation.
Evaluation of visual
Results
Demographic features of all patients evaluated in the study are shown in Table 1. No significant differences were found with respect to mean age between the three groups. In addition, the presence of either diabetes mellitus or systemic hypertension was not significantly different among the groups. However, the mean intraocular pressure was found to be significantly different among the groups (P < 0.05). Of 14 patients with pseudoexfoliation glaucoma, 11 patients had a current history of drug
Discussion
This study showed that at least some hemodynamic parameters in the retrobulbar vessels were altered in patients with pseudoexfoliation syndrome, more prominently in patients with pseudoexfoliation glaucoma.
A definitive explanation was lacking concerning the alterations in the retrobulbar blood flow parameters in pseudoexfoliation syndrome. Such alterations were found in various types of glaucoma. Costa et al,20 in a study of color Doppler imaging in patients with open- or closed-angle glaucoma
References (48)
- et al.
A histopathologic study of iris changes in pseudoexfoliation syndrome
Ophthalmology
(1995) - et al.
Generalized transluminance of the iris and the frequency of the pseudoexfoliation syndrome in the eyes of transient ischemic attack patients
Ophthalmology
(1993) - et al.
Clinical findings and hemodynamic changes associated with severe occlusive carotid artery disease
Ophthalmology
(1997) - et al.
Color Doppler imaging of ophthalmic artery blood flow velocitya study of repeatability and agreement
Ophthalmology
(1997) - et al.
Color Doppler analysis of ocular vessel blood velocity in normal-tension glaucoma
Am J Ophthalmol
(1994) - et al.
Color Doppler imaging and spectral analysis of the optic nerve vasculature in glaucoma
Am J Ophthalmol
(1995) - et al.
Blood-flow velocities of the extraocular vessels in patients with high-tension and normal-tension primary open-angle glaucoma
Am J Ophthalmol
(1997) - et al.
Color Doppler imaging in patients with asymmetric glaucoma and unilateral visual field loss
Am J Ophthalmol
(1996) - et al.
Various glaucomatous optic nerve appearances. A color Doppler imaging study of retrobulbar circulation
Ophthalmology
(1996) - et al.
Vascular aspects in the pathophysiology of glaucomatous optic neuropathy
Surv Ophthalmol
(1999)