Letters to the EditorMYOCARDIAL INFARCTION RISK, EARLOBE CREASE, AND SLEEP APNOEA SYNDROME
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Earlobe crease in women: Evaluation of reproductive factors, alcohol use, and quetelet index and relation to atherosclerotic disease
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2020, Heart and LungCitation Excerpt :Another pathophysiological explanation to the relationship between COPD and DELC is that several conditions including oxidant-antioxidant imbalances in both the lungs and the circulation, gene polymorphisms, activation of transcription factors, increased plasma pro-inflammatory cytokines, and hypoxia cause endothelial dysfunction.22 Diagonal earlobe crease (DELC) is usually absent at birth and in young children and is more common in the elderly.23 Evrengul et al. evaluated 415 patients for the presence of bilateral ELC and revealed that the prevalence of DELC positively correlated with age, hypertension, male gender, and smoking.24
Detection of Frank's sign in the dental setting: A population-based cohort study
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