Elsevier

Vision Research

Volume 42, Issue 22, October 2002, Pages 2555-2559
Vision Research

Undercorrection of myopia enhances rather than inhibits myopia progression

https://doi.org/10.1016/S0042-6989(02)00258-4Get rights and content
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Abstract

The effect of myopic defocus on myopia progression was assessed in a two-year prospective study on 94 myopes aged 9{14 years, randomly allocated to an undercorrected group or a fully corrected control group. The 47 experimental subjects were blurred by approximately +0.75 D (blurring VA to 6/12), while the controls were fully corrected. Undercorrection produced more rapid myopia progression and axial elongation (ANOVA, F(1,374)=14.32, p<0.01). Contrary to animal studies, myopic defocus speeds up myopia development in already myopic humans. Myopia could be caused by a failure to detect the direction of defocus rather than by a mechanism exhibiting a zero-point error.

Keywords

Emmetropization
Refractive error
Myopia

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