BREAST SARCOMA

https://doi.org/10.1016/S0039-6109(05)70445-XGet rights and content

Section snippets

MANAGEMENT

Treatment of primary breast sarcoma is surgical. Controversy exists as to the optimal surgical treatment because the data involving the efficacy of either wide local excision to negative margins or total mastectomy are derived from retrospective analysis involving series of small numbers of patients. The debate stems from retrospective analysis, in which the larger tumors are often treated with mastectomy and the smaller lesions by excision. Margins in the historical series were not always

CYSTOSARCOMA PHYLLODES

Cystosarcoma phyllodes accounts for less than 1% of all breast tumors. The nomenclature represents something of a misnomer in that the lesion is not always associated with cysts and most often does not have the clinical features associated with sarcoma. It derives its name from a description of the lesion over 150 years ago and since that time has been referred to by at least 50 different synonyms.39 Grossly, these lesions have an appearance similar to a fibroadenoma, firm and well

First page preview

First page preview
Click to open first page preview

References (54)

  • K. Antman et al.

    An intergroup phase III randomized study of doxorubicin and dacarbazine with or without ifosfamide and mesna in advanced soft tissue sarcoma

    J Clin Oncol

    (1993)
  • L. Barnes et al.

    Sarcomas of the breast

    Cancer

    (1977)
  • C. Bartoli et al.

    Small sized phyllodes tumor of the breast

    Eur J Surg Oncol

    (1990)
  • J. Berg et al.

    Stromal sarcomas of the breast

    A unified approach to connective tissue sarcomas other than cystosarcoma phyllodes

    (1962)
  • S. Berger et al.

    Mammography of breast sarcoma

    Am J Roentgenol

    (1962)
  • V. Bramwell et al.

    Adjuvant chemotherapy for adult soft tissue sarcoma

    J Clin Oncol

    (1994)
  • N. Bundred et al.

    Long term survival following bilateral breast angiosarcoma

    Eur J Surg Oncol

    (1989)
  • C. Callery et al.

    Sarcoma of the breast. A study of 32 patients with reappraisal of classification and therapy

    Ann Surg

    (1985)
  • E. Casper et al.

    Preoperative and postoperative adjuvant combination chemotherapy for adults with high grade soft tissue sarcoma

    Cancer

    (1994)
  • G.C. Cedermark et al.

    Prognostic factors in cystosarcoma phyllodes

    Cancer

    (1991)
  • K. Chen et al.

    Angiosarcoma of the breast

    Cancer

    (1980)
  • L. Christensen et al.

    Sarcomas of the breast. A clinicopathologic study of 67 patients with long-term follow up

    Eur J Surg Oncol

    (1988)
  • S. Ciatto et al.

    Sarcoma of the breast: A multicenter series of 70 cases

    Neoplasia

    (1992)
  • P. Cohen et al.

    Phyllodes tumor of the breast—pathological and surgical implications

    Breast Dis

    (1994)
  • G. Cohn-Cedarmark et al.

    Prognostic factors in cystosarcoma phyllodes

    Cancer

    (1991)
  • P. Cosmacini et al.

    Phyllodes tumor of the breast: Mammographic appearance in 99 cases

    Eur J Radiol

    (1992)
  • R. Donnell

    Angiosarcoma and other vascular tumors of the breast

    Am J Surg Pathol

    (1981)
  • Cited by (80)

    • High-Grade Spindle Cell Lesions of the Breast: Key Pathologic and Clinical Updates

      2022, Surgical Pathology Clinics
      Citation Excerpt :

      The prognosis highly depends on the histologic type, tumor size, and disease stage. Some unfavorable prognostic factors are older age,94,107 tumor size greater than 5 cm107,108, and the presence of tumor spread or metastasis.93,109 The 5-year DFS rates and OS rates for PBS range from 44% to 66% and 49% to 67%, respectively.89,93,105,108,110

    • Resection and reconstruction following recurrent malignant phyllodes–Case report and review of literature

      2017, Annals of Medicine and Surgery
      Citation Excerpt :

      Reinfuss et al. reported that 2.4% of phyllodes tumors in their series clinically infiltrated the pectoralis major muscle [16]. Moore and Kinne recommend extended excision of involved pectoralis muscle, followed by reconstruction of the chest wall with Marlex mesh and methylmethacrylate [17] Post-operative radiation for cases of chest wall infiltration has also been advocated [14]. Our patient presented with extensive chest wall infiltration involving ribs 3 and 4.

    View all citing articles on Scopus

    Address reprint requests to Michael P. Moore, MD, PhD, Department of Surgery, Columbia Presbyterian Medical Center, 622 West 168th Street, New York, NY 10032

    *

    From the Department of Surgery, Columbia University College of Physicians and Surgeons, New York, New York

    View full text