Utah Growth Study: Growth standards and the prevalence of growth hormone deficiency☆,☆☆,★,★★
Section snippets
METHODS
A prospective prevalence study was designed; this design is particularly useful for studying conditions that may be quantified and yet vary with time.8
Utah is a large state (85,000 square miles) with a population census in 1990 of 1,722,850.9 Seventy-seven percent of the population resides along the Wasatch Front, a narrow corridor 80 miles in length along the Wasatch mountain range in north central Utah. Approximately 11% of the population is composed of minority groups: Hispanic 5%;
RESULTS
A total of 123,948 elementary students, from kindergarten to fifth grade exclusively, were measured in the first year of the survey. We found that a child could be measured and the results recorded in <30 seconds when the process was done properly. Thus a full classroom took <20 minutes and there were few complaints about disruption from teachers or principals. Children absent because of illness represented 4.9% of the school population (Utah State School Board: unpublished data, 1992). In
DISCUSSION
Several growth charts have been constructed from measurements of North American children.1, 2 National Center of Health Statistics data1 provide the most recent and widely used percentile growth charts for height and weight of North American children from 2 to 18 years of age. These data are thought to be representative of childhood growth in the United States. The percentile values for Utah elementary children fit well with the standards for height in North American children.12 The standards
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Prevalence of refractoriness when testing growth hormone levels in children
2023, Growth Hormone and IGF ResearchPresentation and diagnosis of childhood-onset combined pituitary hormone deficiency: A single center experience from over 30 years
2022, eClinicalMedicineCitation Excerpt :Little is known about the incidence of congenital CPHD. The available incidence estimates range from 1/4000-1/10 000, but in fact, these are based on variable short stature and growth hormone deficiency incidence/prevalence estimates and on one optic nerve hypoplasia study.56–61 We studied pediatric CPHD patients treated in the largest tertiary center in Finland, and, after inclusion of only patients with two or more pituitary hormone deficiencies, were able to provide an incidence estimate for congenital CPHD of 1 in 16 000 children.
Screening of GHSR, GHRHR, GH1 genes in isolated growth hormone deficiency disease in Egyptian patients
2024, Egyptian Journal of Medical Human Genetics
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From the Division of Pediatric Endocrinology, Department of Pediatrics, University of Utah Medical Center, Salt Lake City
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Supported by a grant from Genentech, Inc.
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Reprint requests: Rob Lindsay, MD, 508 East South Temple, No. 310, Salt Lake City, UT 84102.
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0022-3476/94/$3.00 + 0 9/20/54999