Scientific paperRectal cancer surgery in patients more than 80 years of age
Section snippets
Patients and methods
From 1980 to 1998, 368 patients were operated on for adenocarcinoma of the rectum in our institution. For the purpose of the study, they were divided into two groups: group 1 included 92 patients (25%) who were 80 years of age or older on first presentation (age range 80 to 91 years; mean age 83.3 years); group 2 included 276 patients (75%) who were younger than 80 years (age range 15 to 79 years; mean age 62.6 years).
The collected data included the sex and operative risk factors (according to
Results
Characteristics of patients and tumors are given in Table 1. There were significant differences with regard to the sex-ratio and the operative risk of patients: among patients over 80 years of age (group 1), 41% were male compared with 59% in patients under 80 years (group 2; chi-square = 8.41, 1 d.f., P = 0.004); 33% of patients were classified as ASA III/IV in group 1 compared with 16% in group 2 (chi-square = 11.32, 1 d.f., P < 0.001). There was no significant difference between the two
Comments
Previous studies about colorectal cancer surgery in the elderly were performed in patients older than 70 [5], [10], 75 [4], [13], 80 [6], [8], [9], [14], [15], [16], [17], or 90 years of age [18]. In the present study, limited to rectal cancer surgery, 80 years was selected as a limit of age for two reasons. Firstly, patients over 80 years of age represent more than 20% of patients [6], [14], this rate being verified in our series. Secondly, some studies have suggested that 80 years represents
References (26)
- et al.
Influence of age on mortality of colon surgery
Am J Surg
(1985) - et al.
Surgery in patients of advanced age
Ann Surg
(1937)- et al.
Major operations in elderly patients
Surgery
(1939) - et al.
Surgery for large bowel cancer in people aged 75 years and older
Dis Colon Rectum
(1986) Colon surgery for cancer in the very elderly. Cost and 3-year survival
Ann Surg
(1986)- et al.
Resectability, operative mortality, and survival of patients in old age with carcinoma of the colon and rectum
Dis Colon Rectum
(1974) - et al.
Abdominal colon and rectal operations in the elderly
Dis Colon Rectum
(1991) - et al.
Colorectal surgery in octogenarians
J Am Coll Surg
(1996) Prognosis of colorectal cancer in the elderly
Br J Surg
(1988)
ASA physical status classifications. A study of consistency of ratings
Anesthesiology
The classification of cancer of the rectum
J Pathol
Colorectal cancer in patients older than 75 years of age
Dis Colon Rectum
Cited by (81)
Association of age with outcomes in locally advanced rectal cancer treated with neoadjuvant therapy followed by surgery
2023, American Journal of SurgeryCitation Excerpt :The treatment of LARC in the elderly has traditionally been individualized and suboptimal, including offering fewer or less intensive surgical resections, neoadjuvant and adjuvant therapies. Arguably, the association of increasing age with higher comorbidities, emergent presentations,17,18 treatment-related complications & mortality4,8,19,20 has been responsible for this. Elderly people, especially those aged ≥70 years have been systematically underrepresented in cancer trials,3,21 despite the federal requirement of representation of minority groups in cancer trials.22
Anticholinergic burden of long-term medication is an independent risk factor for the development of postoperative delirium: A clinical trial
2020, Journal of Clinical AnesthesiaCitation Excerpt :In Europe, it has been estimated that approximately 58% of all cancers and 69% of cancer deaths affect people aged over 65 years [1,2]. This progressive process results in surgery on patients for whom major surgery was considered hazardous only few decades ago [3]. Nowadays, surgery in this age group is considered routine [4].
Colorectal cancer care in elderly patients: Unsolved issues
2016, Digestive and Liver DiseaseThe impact of age on rectal cancer treatment, complications and survival
2022, Research SquareCOVID-19 and the emergency presentation of colorectal cancer
2021, Colorectal Disease