PerspectiveOptical coherence tomography to detect and manage retinal disease and glaucoma
Section snippets
Basic principles and methodology
Optical coherence tomography is based on the principle of Michelson interferometry.9 Low-coherence infrared light coupled to a fiberoptic travels to a beam-splitter and is directed through the ocular media to the retina and to a reference mirror, respectively. Light passing through the eye is reflected by structures in different retinal tissue layers. The distance between the beam-splitter and reference mirror is continuously varied. When the distance between the light source and retinal tissue
Optical coherence tomography for the diagnosis and management of retinal disease
Multiple OCT scan modes are available to evaluate retinal pathology. However, in actual practice, only a few are used routinely. Most commonly, to evaluate and follow macular thickening, an RTM, or FRTM, and cross-sectional images are obtained. To evaluate other disorders, a cross-sectional image may be all that is necessary. Magnified retinal images of high transverse resolution can be obtained using a smaller scan length (as the same number of data points are packed into a shorter distance),
Optical coherence tomography for the diagnosis and management of glaucoma
Optical coherence tomography provides high-resolution measurements and cross-sectional imaging of the retina and the RNFL. For glaucoma applications, an operator-determined circular or linear path is scanned around the optic disk to generate a series of 100 axial reflectance profiles. From these, a real-time two-dimensional tomographic image is constructed (Figure 9). The first reflection measurement is the vitreous-internal limiting membrane interface. The highly reflective interface
Summary and future directions
It is likely that OCT will be used increasingly to diagnose and manage retinal diseases and glaucoma. In the future, improvements in scanning hardware and software will facilitate its use. It is likely that commercial scanners will incorporate ultra-broad spectral bandwidth light sources as they become less costly, a modification that will greatly enhance axial resolution. Several questions still remain regarding the clinical use of OCT. Other instruments, such as the RTA and the HRT, are
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