The American Journal of Medicine
Reflux Associated Apnea in Infants: Evidence for a Laryngeal Chemoreflex☆
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2021, Epilepsy and BehaviorMechanisms and prevention of acid reflux induced laryngospasm in seizing rats
2020, Epilepsy and BehaviorCitation Excerpt :Recent work has proposed the mammalian diving reflex, which strong coactivates both ANS pathways, as a possible cause of SUDEP, and it has been a suspected cause of other types of sudden death for many years [19,20,23–26]. Like the mammalian diving reflex, the laryngeal chemoreflex (LCR) can strongly coactivate both ANS pathways, can cause laryngospasm, and has been implicated in other types of sudden death [23,27–31]. Recent animal work and limited clinical data have proposed laryngospasm as a contributing or even causative factor to the cardiorespiratory collapse seen in SUDEP [30,32–34].
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2020, Experimental NeurologyGastroesophageal Reflux Disease in the Neonatal Intensive Care Unit Infant: Who Needs to Be Treated and What Approach Is Beneficial?
2019, Pediatric Clinics of North AmericaCitation Excerpt :Theoretically, GERD and retrograde aspiration could result from the failure of these mechanisms. Abnormalities of all of these reflexes are unlikely in physiologically healthy infants, which is why most healthy infants are asymptomatic despite having frequent episodes of GER.47–49 Several risk factors for GERD have been identified in infants, and the most common causes are listed in Fig. 3.
Nasal high-frequency oscillatory ventilation inhibits gastroesophageal reflux in the neonatal period
2018, Respiratory Physiology and Neurobiology
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This work was funded by grant HD10993 from the NICHHD.