Bone remodeling and calcium metabolism: A correlated histomorphometric, calcium kinetic, and biochemical study in patients with osteoporosis and Paget's disease☆,☆☆,★
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2018, International Journal of Biological MacromoleculesCitation Excerpt :Unlike many other tissues in the body, bones possess the property of regeneration and remodeling in response to injury. Bone remodeling is influenced by the calcium levels in the blood and the pull of muscles on bone [12–14]. However, in long-bone injuries, the required bone regeneration exceeds the natural potential for its self-healing.
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2010, BoneCitation Excerpt :However, very limited data are available on confirmation of this technique against dynamic bone histomorphometry. Previous studies comparing Ca kinetics to bone histomorphometric measures examined the correlations in healthy vs. disease states of human subjects, such as Paget's disease, rather than the perturbations studied here that may be more relevant to the generally healthy population [22]. It has to be emphasized that certain of the measures derived from histomorphometry and kinetic studies are inherently incommensurable.
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Supported by Grants 3.104.69, 3.804.72, and 3.8710.72 from the Schweiz. Nationalfonds zur Förderung der wissenschaftlichen Forschung.
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This study is part of the doctoral dissertation of Th. Lauffenburger at the University of Basle.
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Presented in part at the Xth European Symposium on Calcified Tissues, Hamburg, Germany, September 1973, and in part at the 58th Tagung der Deutschen Gesellschaft für Pathologie, Interlaken, Switzerland, May 1974.