EEG discriminant analyses of mild head trauma

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Abstract

Measures of EEG power spectral analyses were obtained from a total of 608 mild head trauma patients and 108 age-matched normal subjects. A training-set discriminant function was first developed from 264 mild head-injured patients and 83 age-matched controls yielding an overall discriminant classification accuracy of 94.8%. The first independent cross-validation of the discriminant function using 130 mild head trauma patients and 21 age-matched normals yielded a discriminant classification accuracy of 96.2% for the trauma patients and 90.5% for the normals. A second independent cross-validation of the discriminant function using 51 patients and measures of test-retest reliability from 93 patients yielded classification accuracies ranging between 77.8% and 92.3%. A third independent cross-validation of 70 mild head-injured patients tested at a different location with a different EEG computer system yielded a discriminant accuracy of 92.8%. The discriminating EEG power spectral analyses indicated 3 classes of neurophysiological variables which are attributable to mechanical head injury: (1) increased coherence and decreased phase in frontal and frontal-temporal regions; (2) decreased power differences between anterior and posterior cortical regions; and (3) reduced alpha power in posterior cortical regions.

References (35)

  • P.G. Bernad

    Closed head injury (CHI) type I and II with post concussion syndrome (PCS)

    Clin. Electroenceph.

    (1988)
  • J.S. Bendat et al.

    Engineering Applications of Correlation and Spectral Analyses

    (1980)
  • E.D. Bigler

    Neuropathology of acquired cerebral trauma

    J. Learn. Disabil.

    (1987)
  • W.F. Caveness

    Epilepsy, a product of trauma in our time

    Epilepsia

    (1976)
  • T.B. Ducker et al.

    Comprehensive assessment of coma in neurotrauma patients

  • T.A. Gennarelli

    Mechanisms and pathophysiology of cerebral concussion

    J. Head Trauma Rehab.

    (1986)
  • T.A. Gennarelli et al.

    Diffuse axonal injury and traumatic coma in the primate

    Ann. Neurol.

    (1982)
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