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CD5 Positive B Lymphoblastic Leukemia: Report of a Case with Review of Literature

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Indian Journal of Hematology and Blood Transfusion Aims and scope Submit manuscript

Abstract

We report a rare CD5 positive B cell acute lymphoblastic leukemia (B-ALL) with a review of the clinopathological features and prognosis of previously reported cases in the literature. The aberrant expression of CD 5 antigen is uncommon in B-ALL; the morphological differential diagnosis includes blastic mantle cell lymphoma, denovo CD5+ diffuse large B cell lymphoma and secondary diffuse large cell lymphoma/Richter’s transformation. CD5+ B cell ALL is commonly reported in younger patients (<18 years). Though the expression of T cell antigens is reported to have poor prognosis, the experience with CD5+ B-ALL is limited to draw any firm conclusion regarding its prognosis.

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The authors declare that there is no conflict of interests.

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Authors and Affiliations

  1. Department of Hematology, Level 5, Research Block A, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012, India

    Sreejesh Sreedharanunni & Narender Kumar

  2. Department of Internal Medicine, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012, India

    Alka Khadwal

Authors
  1. Sreejesh Sreedharanunni
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  2. Narender Kumar
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  3. Alka Khadwal
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Correspondence to Narender Kumar.

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Sreedharanunni, S., Kumar, N. & Khadwal, A. CD5 Positive B Lymphoblastic Leukemia: Report of a Case with Review of Literature. Indian J Hematol Blood Transfus 32 (Suppl 1), 1–4 (2016). https://doi.org/10.1007/s12288-014-0485-y

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  • DOI: https://doi.org/10.1007/s12288-014-0485-y

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