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Kommentar zu den 2015-Leitlinien der Europäischen Gesellschaft für Kardiologie zur Infektiösen Endokarditis

Commentary on the 2015 European Society of Cardiology guidelines for infectious endocarditis

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Zusammenfassung

Die 2015 publizierten Endokarditisleitlinien der Europäischen Gesellschaft für Kardiologie (ESC) geben praktische Hinweise zur Diagnostik und Therapie der Endokarditis. Veränderungen haben sich insbesondere ergeben durch Verbesserung in der Bildgebung (CT, nuklearmedizinische Bildgebung), die nun fest in die Leitlinien und die modifizierten Duke-Kriterien integriert sind. Therapeutische Entscheidungen werden verbessert durch die Einführung von interdisziplinären „Endokarditisteams“. Therapeutisch legt die erste randomisierte Studie eine frühe Operation bei Patienten mit Embolierisiko nahe, außerdem konnten antimikrobielle Strategien optimiert werden.

Abstract

The 2015 European Society of Cardiology (ESC) endocarditis guidelines give advice on how to diagnose and treat endocarditis. Recommendations were changed due to improved imaging modalities (CT, nuclear imaging) that are now integrated in the modified Duke criteria. Therapeutic decision-making is improved by interdisciplinary endocarditis teams. Therapeutically, the first randomized study suggests early operation in patients with increased embolic risk; furthermore, antimicrobial strategies could be optimized.

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Literatur

  1. Amraoui S, Sohal M, Li A, Williams S, Scully P, Jackson T, Claridge S, Behar J, Ritter P, Barandon L, Ploux S, Bordachar P, Rinaldi CA (2015) Comparison of delayed transvenous reimplantation and immediate surgical epicardial approach in pacing-dependent patients undergoing extraction of infected permanent pacemakers. Heart Rhythm 12:1209–1215

    Article  PubMed  Google Scholar 

  2. Force M, Habib G, Lancellotti P, Antunes MJ, Bongiorni MG, Casalta JP, Del Zotti F, Dulgheru R, El Khoury G, Erba PA, Iung B, Miro JM, Mulder BJ, Plonska-Gosciniak E, Price S, Roos-Hesselink J, Snygg-Martin U, Thuny F, Tornos MP, Vilacosta I, Zamorano JL, Document R, Erol C, Nihoyannopoulos P, Aboyans V, Agewall S, Athanassopoulos G, Aytekin S, Benzer W, Bueno H, Broekhuizen L, Carerj S, Cosyns B, De Backer J, De Bonis M, Dimopoulos K, Donal E, Drexel H, Flachskampf FA, Hall R, Halvorsen S, Hoen B, Kirchhof P, Lainscak M, Leite-Moreira AF, Lip GY, Mestres CA, Piepoli MF, Punjabi PP, Rapezzi C, Rosenhek R, Siebens K, Tamargo J, Walker DM (2015) 2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC)Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM. Eur Heart J 36:3075–3128 (Authors/Task) doi:10.1093/eurheartj/ehv319

    Article  Google Scholar 

  3. Baddour LM, Wilson WR, Bayer AS, Fowler VG Jr., Tleyjeh IM, Rybak MJ, Barsic B, Lockhart PB, Gewitz MH, Levison ME, Bolger AF, Steckelberg JM, Baltimore RS, Fink AM, O’Gara P, Taubert KA, American Heart Association Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular Disease in the Young, Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and Stroke Council (2015) Infective Endocarditis in adults: diagnosis, antimicrobial therapy, and management of complications: A scientific statement for Healthcare professionals from the american heart association. Circulation 132:1435–1486. doi:10.1161/CIR.0000000000000296

    Article  CAS  PubMed  Google Scholar 

  4. Botelho-Nevers E, Thuny F, Casalta JP, Richet H, Gouriet F, Collart F, Riberi A, Habib G, Raoult D (2009) Dramatic reduction in infective endocarditis-related mortality with a management-based approach. Arch Intern Med 169:1290–1298. doi:10.1001/archinternmed.2009.192

    Article  PubMed  Google Scholar 

  5. Fernandez J, Abbanat D, Shang W, He W, Amsler K, Hastings J, Queenan AM, Melton JL, Barron AM, Flamm RK, Lynch AS (2012) Synergistic activity of ceftobiprole and vancomycin in a rat model of infective endocarditis caused by methicillin-resistant and glycopeptide-intermediate Staphylococcus aureus. Antimicrob Agents Chemother 56:1476–1484. doi:10.1128/AAC.06057-11

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Feuchtner GMSP, Dichtl WST, Bonatti JSH, Mueller SPA, Mueller LBT, Wolf FAH (2009) Multislice computed tomography in infective endocarditis: comparison with transesophageal echocardiography and intraoperative findings. J Am Coll Cardiol 53:436–444. doi:10.1016/j.jacc.2008.01.077

    Article  PubMed  Google Scholar 

  7. Jacqueline C, Caillon J, Le Mabecque V, Miegeville AF, Hamel A, Bugnon D, Ge JY, Potel G (2007) In vivo efficacy of ceftaroline (PPI-0903), a new broad-spectrum cephalosporin, compared with linezolid and vancomycin against methicillin-resistant and vancomycin-intermediate Staphylococcus aureus in a rabbit endocarditis model. Antimicrob Agents Chemother (Bethesda) 51:3397–3400. doi:10.1128/AAC.01242-06

    Article  CAS  Google Scholar 

  8. Kang DH, Kim YJ, Kim SH, Sun BJ, Kim DH, Yun SC, Song JM, Choo SJ, Chung CH, Song JK, Lee JW, Sohn DW (2012) Early surgery versus conventional treatment for infective endocarditis. N Engl J Med 366:2466–2473. doi:10.1056/NEJMoa1112843

    Article  CAS  PubMed  Google Scholar 

  9. Lefort A, Pavie J, Garry L, Chau F, Fantin B (2004) Activities of dalbavancin in vitro and in a rabbit model of experimental endocarditis due to Staphylococcus aureus with or without reduced susceptibility to vancomycin and teicoplanin. Antimicrob Agents Chemother (Bethesda) 48:1061–1064

    Article  CAS  Google Scholar 

  10. Mylotte DAA, Theriault-Lauzier PDM, Girgis MAW, Chetrit MGC, Mamane SSI, Buithieu JBL, Varennes BLK de, Lange RMG, Virmani RPN (2015) Transcatheter heart valve failure: a systematic review. Eur Heart J 36:1306–1327. doi:10.1093/eurheartj/ehu388

    Article  PubMed  Google Scholar 

  11. Saby L, Laas O, Habib G, Cammilleri S, Mancini J, Tessonnier L, Casalta JP, Gouriet F, Riberi A, Avierinos JF, Collart F, Mundler O, Raoult D, Thuny F (2013) Positron emission tomography/computed tomography for diagnosis of prosthetic valve endocarditis: increased valvular 18F-fluorodeoxyglucose uptake as a novel major criterion. J Am Coll Cardiol 61:2374–2382. doi:10.1016/j.jacc.2013.01.092

    Article  PubMed  Google Scholar 

  12. Thuny F, Grisoli D, Collart F, Habib G, Raoult D (2012) Management of infective endocarditis: challenges and perspectives. Lancet 379:965–975. doi:10.1016/S0140-6736(11)60755-1

    Article  PubMed  Google Scholar 

  13. Tornos P, Iung B, Permanyer-Miralda G, Baron G, Delahaye F, Gohlke-Barwolf C, Butchart EG, Ravaud P, Vahanian A (2005) Infective endocarditis in Europe: lessons from the Euro heart survey. Heart 91:571–575. doi:10.1136/hrt.2003.032128

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Wilbring M, Irmscher L, Alexiou K, Matschke K, Tugtekin SM (2014) The impact of preoperative neurological events in patients suffering from native infective valve endocarditis. Interact Cardiovasc Thorac Surg 18:740–747. doi:10.1093/icvts/ivu039

    Article  PubMed  Google Scholar 

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Correspondence to S. Frantz.

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Den Interessenkonflikt der Autoren finden Sie online auf der DGK-Homepage unter http://leitlinien.dgk.org/ bei der entsprechenden Publikation.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

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B. Levenson für die Kommission für Klinische Kardiologie der DGK

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Frantz, S., Buerke, M., Horstkotte, D. et al. Kommentar zu den 2015-Leitlinien der Europäischen Gesellschaft für Kardiologie zur Infektiösen Endokarditis. Kardiologe 10, 142–148 (2016). https://doi.org/10.1007/s12181-016-0058-4

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