Abstract
Littoral cell angiomas (LCAs) are rare splenic vascular neoplasms that arise from the cells lining the red pulp sinuses. The clinical course is benign and in most cases asymptomatic. However, as has been described in the literature, we have seen an association with malignant neoplasms and haematological disorders. The definitive diagnosis is made on histology and confirmed with immunohistochemistry. The use of percutaneous fine-needle aspiration biopsy (FNA) in preoperative diagnosis is controversial.
Similar content being viewed by others
References
Falk S, Stutte HF, Frizzera G (1991) Littoral cell angioma. A novel splenic vascular lesion demonstrating histiocytic differentiation. Am J Surg Pathol 15:1023–1033
Nájera L, Dotor AM, Santoja C (2006) Angioma esplénico de células litorales. Descripción de un caso y revisión de la literatura. Rev Esp Patología 39
Ramdall RB, Alasio TM, Cai G, Yang GC (2007) Primary vascular neoplasms unique to the spleen: littoral cell angioma and splenic hamartoma diagnosis by fine-needle aspiration biopsy. Diagn Cytopathol 35:137–142
Batt S, Huang J, Dogra V (2007) Littoral cell angioma of the spleen. AJR Am J Roentgenol 188:1365–1366
Bi CF, Jiang LL, Li Z, Liu WP (2007) Littoral cell angioma of spleen: a clinicopathologic study of 17 cases. Zhonghua Bing Li Xue Za Zhi 36:239–243
Jonhson C, Goyal M, Kim B, Wasdahl D, Nazinitsky K (2007) Littoral cell angioma. Clinical Imaging 31:27–31
Heese J, Bocklage T (2000) Specimen fine-needle aspiration cytology of littoral cell angioma with histologic and inmunohistochemical confirmation. Diagn Cytopathol 22:39–44
Lucey BC, Boland GW, Maher MM et al (2002) Percutaneous nonvascular splenic intervention: a 10 year review. AJR Am J Roentgenol 179:1591–1596
Keogan MT, Freed KS, Paulson EK et al (1999) Imaging-guided percutaneous biopsy of local splenic lesions: update on safety and effectiveness. AJR Am J Roentgenol 172:933–937
Collins GL, Morgan MB, Taylor FM 3rd (2003) Littoral cell angiomatosis with poorly differentiated adenocarcinoma of the lung. Ann Diagn Pathol 7:54–59
Bisceglia M, Sickel JZ, Giangaspero F et al (1998) Littoral cell angioma of the spleen: an additional report of tour cases with emphasis on the association with visceral organ cancers. Tumori 84:595–599
Blansfield JA, Goldhahn RT Jr, Josloff RK (2005) Littoral cell angioma of the spleen treated by laparoscopic splenectomy. JSLS 9:222–224
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Priego, P., Velasco, G.R., Griffith, P.S. et al. Littoral cell angioma of the spleen. Clin Transl Oncol 10, 61–63 (2008). https://doi.org/10.1007/s12094-008-0155-3
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12094-008-0155-3