Skip to main content

Advertisement

Log in

The Growing Problem of Stroke among Young Adults

  • Stroke (C Sila, Section Editor)
  • Published:
Current Cardiology Reports Aims and scope Submit manuscript

Abstract

Although overall stroke incidence has been declining in developed countries, there is evidence that stroke in the young is increasing. Increasing incidence may be particularly pronounced among minorities in whom historically a higher burden of stroke has been reported. Compared with older adults, time spent with disability is longer for those affected at younger ages, and new data suggests that among 30-day young adult stroke survivors, increased mortality persists for as long as 20 years. Stroke in young adults is often missed by less experienced clinicians due to its unexpectedness, leading to lost opportunities for intervention. The causes and risk factors for stroke in the young are often rare or undetermined, but young adults with stroke also have a high burden of traditional cardiovascular risk factors, including hypertension, diabetes, obesity, and substance abuse. Disseminating awareness and promoting research on young adult stroke are steps towards reducing the burden of stroke.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, Borden WB, et al. Heart disease and stroke statistics–2012 update: a report from the American Heart Association. Circulation. 2012;125:e2–e220.

    Article  PubMed  Google Scholar 

  2. Carandang R, Seshadri S, Beiser A, Kelly-Hayes M, Kase CS, Kannel WB, et al. Trends in incidence, lifetime risk, severity, and 30-day mortality of stroke over the past 50 years. JAMA. 2006;296:2939–46.

    Article  PubMed  CAS  Google Scholar 

  3. Rothwell PM, Coull AJ, Giles MF, Howard SC, Silver LE, Bull LM, et al. Change in stroke incidence, mortality, case-fatality, severity, and risk factors in Oxfordshire, UK from 1981 to 2004 (Oxford Vascular Study). Lancet. 2004;363:1925–33.

    Article  PubMed  CAS  Google Scholar 

  4. Cabral NL, Goncalves AR, Longo AL, Moro CH, Costa G, Amaral CH, et al. Trends in stroke incidence, mortality and case fatality rates in Joinville, Brazil: 1995-2006. J Neurol Neurosurg Psychiatry. 2009;80:749–54.

    Article  PubMed  CAS  Google Scholar 

  5. •• Lloyd-Jones D, Adams RJ, Brown TM, Carnethon M, Dai S, De Simone G, et al. Heart disease and stroke statistics--2010 update: a report from the American Heart Association. Circulation. 2010;121:e46–e215. This paper defines the metrics for cardiovascular health in adults and children. The AHA will use this metric to monitor progress towards their 2020 Impact Goals: "to improve cardiovascular health and reduce cardiovascular diseases and stroke by 20% in all Americans".

    Article  PubMed  Google Scholar 

  6. • Kissela BM, Khoury JC, Alwell K, Moomaw CJ, Woo D, Adeoye O, et al. Age at stroke: temporal trends in stroke incidence in a large, biracial population. Neurology. 2012;79:1781–7. This is a population-based study of temporal trends in stroke incidence from 1993/1994, 1999, and 2005. The increase in stroke incidence was comparatively greater for younger adults more than older adults. The temporal trend was most pronounced for Blacks.

    Article  PubMed  Google Scholar 

  7. • George MG, Tong X, Kuklina EV, Labarthe DR. Trends in stroke hospitalizations and associated risk factors among children and young adults, 1995-2008. Ann Neurol. 2011;70:713–21. This analysis of children and young adults in the Nationwide Inpatient Sample of the Healthcare Cost and Utilization Project compared hospitalizations for stroke and among those patients, risk factors for stroke from 1995-2008. The prevalence of hospitalizations for acute ischemic stroke compared with other stroke increased and the prevalence of traditional stroke risk factors increased over the study period.

    Article  PubMed  CAS  Google Scholar 

  8. Gandhi SK, McKinney JS, Sedjro JE, Cosgrove NM, Cabrera J, Kostis JB. Temporal trends in incidence and long-term case fatality of stroke among children from 1994 to 2007. Neurology. 2012;78(24):1923–9.

    Google Scholar 

  9. Vaartjes I, O'Flaherty M, Capewell S, Kappelle J, Bots M. Remarkable decline in ischemic stroke mortality is not matched by changes in incidence. Stroke. 2013;44:591–7.

    Article  PubMed  Google Scholar 

  10. •• Sacco RL, Kasner SE, Broderick JP, Caplan LR, Connors JJ, Culebras A, et al. An updated definition of stroke for the 21st century: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2013;44(7):2064–89. A redefinition of stroke updated for the 21st century. Advances in neuroimaging and neuropathology have introduced inconsistency into former clinically based stroke definitions and necessitate this reconsideration of how stroke should be defined.

  11. Diaz-Guzman J, Egido JA, Gabriel-Sanchez R, Barbera-Comes G, Fuentes-Gimeno B, Fernandez-Perez C. Stroke and transient ischemic attack incidence rate in Spain: the IBERICTUS study. Cerebrovasc Dis. 2012;34:272–81.

    Article  PubMed  Google Scholar 

  12. Putaala J, Yesilot N, Waje-Andreassen U, Pitkaniemi J, Vassilopoulou S, Nardi K, et al. Demographic and geographic vascular risk factor differences in European young adults with ischemic stroke: the 15 cities young stroke study. Stroke. 2012;43:2624–30.

    Article  PubMed  Google Scholar 

  13. Kittner SJ, McCarter RJ, Sherwin RW, Sloan MA, Stern BJ, Johnson CJ, et al. Black-white differences in stroke risk among young adults. Stroke. 1993;24(12 Suppl):I13–5. discussion I20–1.

    PubMed  CAS  Google Scholar 

  14. Kittner SJ, Stern BJ, Wozniak M, Buchholz DW, Earley CJ, Feeser BR, et al. Cerebral infarction in young adults: the Baltimore-Washington Cooperative Young Stroke Study. Neurology. 1998;50:890–4.

    Article  PubMed  CAS  Google Scholar 

  15. Jacobs BS, Boden-Albala B, Lin IF, Sacco RL. Stroke in the young in the northern Manhattan stroke study. Stroke. 2002;33:2789–93.

    Article  PubMed  Google Scholar 

  16. Kleindorfer DO, Khoury J, Moomaw CJ, Alwell K, Woo D, Flaherty ML, et al. Stroke incidence is decreasing in whites but not in blacks: a population-based estimate of temporal trends in stroke incidence from the Greater Cincinnati/Northern Kentucky Stroke Study. Stroke. 2010;41:1326–31.

    Article  PubMed  Google Scholar 

  17. • Ji R, Schwamm LH, Pervez MA, Singhal AB. Ischemic stroke and transient ischemic attack in young adults: risk factors, diagnostic yield, neuroimaging, and thrombolysis. JAMA Neurol. 2013;70:51–7. This is a recent single-center analysis of young adult (18–45 years) participants in their Get with the Guidelines-Stroke database from 2005-2010. The study reports on the prevalence of stroke etiologies, risk factors, findings from extensive diagnostic evaluations. and outcome at hospital discharge including symptomatic brain hemorrhage when accounting for thrombolysis treatment.

    Article  PubMed  Google Scholar 

  18. Toni D, Ahmed N, Anzini A, Lorenzano S, Brozman M, Kaste M, et al. Intravenous thrombolysis in young stroke patients: results from the SITS-ISTR. Neurology. 2012;78:880–7.

    Article  PubMed  CAS  Google Scholar 

  19. Putaala J, Strbian D, Mustanoja S, Haapaniemi E, Kaste M, Tatlisumak T. Functional outcome in young adult ischemic stroke: impact of lipoproteins. Acta Neurol Scand. 2013;127:61–9.

    Article  PubMed  CAS  Google Scholar 

  20. Arntz R, Rutten-Jacobs L, Maaijwee N, Schoonderwaldt H, Dorresteijn L, van Dijk E, et al. Post-stroke epilepsy in young adults: a long-term follow-up study. PLoS One. 2013;8:e55498.

    Article  PubMed  CAS  Google Scholar 

  21. • Rutten-Jacobs LC, Arntz RM, Maaijwee NA, Schoonderwaldt HC, Dorresteijn LD, van Dijk EJ, et al. Long-term mortality after stroke among adults aged 18 to 50 years. JAMA. 2013;309:1136–44. A novel study on 20-year mortality among 30-day young adult stroke survivors finds consistently higher mortality among stroke survivors compared with expected mortality for age. Mortality followed a U-shaped curve with high risk early and after 5–6 years.

    Article  PubMed  CAS  Google Scholar 

  22. Hankey GJ. Stroke in young adults: implications of the long-term prognosis. JAMA. 2013;309:1171–2.

    Article  PubMed  CAS  Google Scholar 

  23. Eriksson M, Carlberg B, Eliasson M. The disparity in long-term survival after a first stroke in patients with and without diabetes persists: the Northern Sweden MONICA study. Cerebrovasc Dis. 2012;34:153–60.

    Article  PubMed  Google Scholar 

  24. Putaala J, Haapaniemi E, Gordin D, Liebkind R, Groop PH, Kaste M, et al. Factors associated with impaired kidney function and its impact on long-term outcome in young ischemic stroke. Stroke. 2011;42:2459–64.

    Article  PubMed  Google Scholar 

  25. Greisenegger S, Zehetmayer S, Ferrari J, Lang W, Fizek J, Auff E, et al. Clinical predictors of death in young and middle-aged patients with ischemic stroke or transient ischemic attack: long-term results of the Vienna Stroke Registry: clinical predictors of ischemic stroke mortality in patients <60 years. J Neurol. 2011;258:1105–13.

    Article  PubMed  Google Scholar 

  26. Adams Jr HP, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multi-center clinical trial. TOAST, Trial of Org 10172 in Acute Stroke Treatment. Stroke. 1993;24:35–41.

    Article  PubMed  Google Scholar 

  27. Shay CM, Ning H, Daniels SR, Rooks CR, Gidding SS, Lloyd-Jones DM. Status of cardiovascular health in US adolescents: prevalence estimates from the National Health and Nutrition Examination Surveys (NHANES) 2005–2010. Circulation. 2013;127:1369–76.

    Article  PubMed  Google Scholar 

  28. von Sarnowski B, Putaala J, Grittner U, Gaertner B, Schminke U, Curtze S, et al. Lifestyle risk factors for ischemic stroke and transient ischemic attack in young adults in the Stroke in Young Fabry Patients study. Stroke. 2013;44:119–25.

    Article  Google Scholar 

  29. de los Rios F, Kleindorfer DO, Khoury J, Broderick JP, Moomaw CJ, Adeoye O, et al. Trends in substance abuse preceding stroke among young adults: a population-based study. Stroke. 2012;43:3179–83.

    Article  PubMed  Google Scholar 

  30. Bibbins-Domingo K, Coxson P, Pletcher MJ, Lightwood J, Goldman L. Adolescent overweight and future adult coronary heart disease. N Engl J Med. 2007;357:2371–9.

    Article  PubMed  CAS  Google Scholar 

  31. Organization WH. Global Health Observatory (GHO): overweight and obesity.

  32. Ogden CL, Flegal KM, Carroll MD, Johnson CL. Prevalence and trends in overweight among US children and adolescents, 1999–2000. JAMA. 2002;288:1728–32.

    Article  PubMed  Google Scholar 

  33. Fryar CD, Cynthia L. Ogden CL. Prevalence of obesity among children and adolescents: United States, trends 1963–1965 through 2009-2010. Available at: http://www.cdc.gov/nchs/data/hestat/obesity_child_09_10/obesity_child_09_10.htm. Accessed 1 June 2013.

  34. Yanovski SZ, Yanovski JA. Obesity prevalence in the United States—up, down, or sideways? N Engl J Med. 2011;364:987–9.

    Article  PubMed  CAS  Google Scholar 

  35. Flegal KM, Carroll MD, Ogden CL, Curtin LR. Prevalence and trends in obesity among US adults, 1999-2008. JAMA. 2010;303:235–41.

    Article  PubMed  CAS  Google Scholar 

  36. Ogden CL, Carroll MD, Curtin LR, Lamb MM, Flegal KM. Prevalence of high body mass index in US children and adolescents, 2007-2008. JAMA. 2010;303:242–9.

    Article  PubMed  CAS  Google Scholar 

  37. Fox CS, Pencina MJ, Meigs JB, Vasan RS, Levitzky YS, D'Agostino Sr RB. Trends in the incidence of type 2 diabetes mellitus from the 1970s to the 1990s: the Framingham Heart Study. Circulation. 2006;113:2914–8.

    Article  PubMed  Google Scholar 

  38. Mokdad AH, Ford ES, Bowman BA, Dietz WH, Vinicor F, Bales VS, et al. Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA. 2003;289:76–9.

    Article  PubMed  Google Scholar 

  39. Nam HS, Kim HC, Kim YD, Lee HS, Kim J, Lee DH, et al. Long-term mortality in patients with stroke of undetermined etiology. Stroke. 2012;43:2948–56.

    Article  PubMed  Google Scholar 

  40. Ince B, Benbir G. Letter by Ince and Benbir regarding article, "long-term mortality in patients with stroke of undetermined etiology". Stroke. 2013;44:e17.

    Article  PubMed  Google Scholar 

  41. Ducrocq X, Lacour JC, Debouverie M, Bracard S, Girard F, Weber M. Cerebral ischemic accidents in young subjects. A prospective study of 296 patients aged 16 to 45 years. Rev Neurol (Paris). 1999;155:575–82.

    CAS  Google Scholar 

  42. Giroud M, Fayolle H, Andre N, Dumas R, Becker F, Martin D, et al. Incidence of internal carotid artery dissection in the community of Dijon. J Neurol Neurosurg Psychiatry. 1994;57:1443.

    Article  PubMed  CAS  Google Scholar 

  43. Bogousslavsky J, Regli F. Ischemic stroke in adults younger than 30 years of age. Cause and prognosis. Arch Neurol. 1987;44:479–82.

    Article  PubMed  CAS  Google Scholar 

  44. Volker W, Dittrich R, Grewe S, Nassenstein I, Csiba L, Herczeg L, et al. The outer arterial wall layers are primarily affected in spontaneous cervical artery dissection. Neurology. 2011;76:1463–71.

    Article  PubMed  CAS  Google Scholar 

  45. Morris SA, Orbach DB, Geva T, Singh MN, Gauvreau K, Lacro RV. Increased vertebral artery tortuosity index is associated with adverse outcomes in children and young adults with connective tissue disorders. Circulation. 2011;124:388–96.

    Article  PubMed  Google Scholar 

  46. Olin JW, Froehlich J, Gu X, Bacharach JM, Eagle K, Gray BH, et al. The United States Registry for Fibromuscular Dysplasia: results in the first 447 patients. Circulation. 2012;125:3182–90.

    Article  PubMed  Google Scholar 

  47. Scott RM, Smith ER. Moyamoya disease and moyamoya syndrome. N Engl J Med. 2009;360:1226–37.

    Article  PubMed  CAS  Google Scholar 

  48. Duan L, Bao XY, Yang WZ, Shi WC, Li DS, Zhang ZS, et al. Moyamoya disease in China: its clinical features and outcomes. Stroke. 2012;43:56–60.

    Article  PubMed  Google Scholar 

  49. • Kenet G, Lutkhoff LK, Albisetti M, Bernard T, Bonduel M, Brandao L, et al. Impact of thrombophilia on risk of arterial ischemic stroke or cerebral sinovenous thrombosis in neonates and children: a systematic review and meta-analysis of observational studies. Circulation. 2010;121:1838–47. The largest meta-analysis of thrombophilia on risk of first childhood and neonatal stroke. Each thrombophilia trait was associated with first stroke in children: antithrombin deficiency, protein C deficiency, protein S deficiency, factor V G1691A, factor II G20210A, MTHFR C677T, antiphospholipid antibodies, and elevated lipoprotein(a).

    Article  PubMed  Google Scholar 

  50. Hamedani AG, Cole JW, Cheng Y, Sparks MJ, O'Connell JR, Stine OC, et al. Factor V Leiden and Ischemic Stroke Risk: the Genetics of Early Onset Stroke (GEOS) Study. J Stroke Cerebrovasc Dis. 2013;22:419–23.

    Article  PubMed  Google Scholar 

  51. Schurks M, Rist PM, Bigal ME, Buring JE, Lipton RB, Kurth T. Migraine and cardiovascular disease: systematic review and meta-analysis. BMJ. 2009;339:b3914.

    Article  PubMed  Google Scholar 

  52. Kurth T, Chabriat H, Bousser MG. Migraine and stroke: a complex association with clinical implications. Lancet Neurol. 2012;11:92–100.

    Article  PubMed  Google Scholar 

  53. Schurks M, Rist PM, Shapiro RE, Kurth T. Migraine and mortality: a systematic review and meta-analysis. Cephalalgia. 2011;31:1301–14.

    Article  PubMed  Google Scholar 

  54. Bhattacharya P, Taraman S, Shankar L, Chaturvedi S, Madhavan R. Clinical profiles, complications, and disability in cocaine-related ischemic stroke. J Stroke Cerebrovasc Dis. 2011;20:443–9.

    Article  PubMed  Google Scholar 

  55. • Lidegaard O, Lokkegaard E, Jensen A, Skovlund CW, Keiding N. Thrombotic stroke and myocardial infarction with hormonal contraception. N Engl J Med. 2012;366:2257–66. This is a 15-year population based cohort study on risk of thrombotic stroke and myocardial infarction among young women (15–49 years) with no history of cardiovascular disease. Use of all hormonal contraceptions was associated with a small increased risk of an outcome event.

    Article  PubMed  CAS  Google Scholar 

  56. Petitti DB. Hormonal contraceptives and arterial thrombosis–not risk-free but safe enough. N Engl J Med. 2012;366:2316–8.

    Article  PubMed  CAS  Google Scholar 

  57. • Thaler DE, Ruthazer R, Di Angelantonio E, Di Tullio MR, Donovan JS, Elkind MS, et al. Neuroimaging findings in cryptogenic stroke patients with and without patent foramen ovale. Stroke. 2013;44:675–80. This international collaborative individual patient meta-analysis draws on data from 12 component databases to study the association between imaging characteristics of stroke and the likelihood of finding a PFO. The investigators found that patients with strokes that were large, radiologically apparent, superficially located, or unassociated with prior radiological infarcts were more likely to have PFOs than were those with unapparent, smaller, or deep strokes, or those with other chronic infarcts.

    Article  PubMed  Google Scholar 

  58. • Kent DM RR, Weimar C, Mas JL, Serena J, Homma S, Di Angelantonio E, et al. The Risk of Paradoxical Embolism (RoPE) Study: a score to identify cryptogenic stroke patients whose stroke is likely attributable to patent foramen ovale. Neurology. [In press]. This paper describes the development of the Risk of Paradoxical Embolism (RoPE) score, a simple 10 point scoring system for use among patients with unexplained stroke. Variables negatively associated with a PFO in patients with unexplained stroke included age, diabetes, hypertension, smoking, prior stroke or TIA, and absence of a cortical stroke on neuroimaging. The 10-point RoPE score includes a point for each of the 5 non-age factors and 1 point for roughly each full decade over age 18 (up to 5 points). Patients with higher scores (ie, fewer risk factors) were more likely to have PFOs, but were also less likely to have a stroke recurrence. These data and the scoring system may be useful in future trials of PFO closure.

  59. • Carroll JD, Saver JL, Thaler DE, Smalling RW, Berry S, MacDonald LA, et al. Closure of patent foramen ovale vs medical therapy after cryptogenic stroke. N Engl J Med. 2013;368:1092–100. This is a recent randomized clinical trial comparing closure of a patent foramen ovale with medical therapy among young adults (18–60) with a cryptogenic stroke. For the primary outcome of stroke recurrence, there was no statistically significant difference between the groups, but the study may have been underpowered. Adverse events were similar between the groups.

    Article  PubMed  CAS  Google Scholar 

  60. • Meier B, Kalesan B, Mattle HP, Khattab AA, Hildick-Smith D, Dudek D, et al. Percutaneous closure of patent foramen ovale in cryptogenic embolism. N Engl J Med. 2013;368:1083–91. Another recent randomized clinical trial comparing closure of a patent foramen ovale with medical therapy, this trial included adults <60 years with an ischemic stroke, TIA, or a peripheral thromboembolic event. The rate of a primary outcome event (death, nonfatal stroke, TIA, or peripheral embolism) was not statistically different in the closure and the medical-therapy groups, but this study also may have been underpowered.

    Article  PubMed  CAS  Google Scholar 

  61. Ferro JM, Canhao P, Stam J, Bousser MG, Barinagarrementeria F. Prognosis of cerebral vein and dural sinus thrombosis: results of the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT). Stroke. 2004;35:664–70.

    Article  PubMed  Google Scholar 

  62. Saposnik G, Barinagarrementeria F, Brown Jr RD, Bushnell CD, Cucchiara B, Cushman M, et al. Diagnosis and management of cerebral venous thrombosis: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2011;42:1158–92.

    Article  PubMed  Google Scholar 

  63. Naess H, Waje-Andreassen U, Thomassen L, Nyland H, Myhr KM. Health-related quality of life among young adults with ischemic stroke on long-term follow-up. Stroke. 2006;37:1232–6.

    Article  PubMed  Google Scholar 

  64. Savitz SI, Caplan LR, Edlow JA. Pitfalls in the diagnosis of cerebellar infarction. Acad Emerg Med. 2007;14:63–8.

    Article  PubMed  Google Scholar 

  65. Kuruvilla A, Bhattacharya P, Rajamani K, Chaturvedi S. Factors associated with misdiagnosis of acute stroke in young adults. J Stroke Cerebrovasc Dis. 2011;20:523–7.

    Article  PubMed  Google Scholar 

  66. Mohamed W, Bhattacharya P, Chaturvedi S. Early access to a neurologist reduces the rate of missed diagnosis in young strokes. J Stroke Cerebrovasc Dis. 2013. doi:10.1016/j.jstrokecerebrovasdis.2013.01.013

  67. Niinikoski H, Lagstrom H, Jokinen E, Siltala M, Ronnemaa T, Viikari J, et al. Impact of repeated dietary counseling between infancy and 14 years of age on dietary intakes and serum lipids and lipoproteins: the STRIP study. Circulation. 2007;116:1032–40.

    Article  PubMed  CAS  Google Scholar 

  68. Niinikoski H, Jula A, Viikari J, Ronnemaa T, Heino P, Lagstrom H, et al. Blood pressure is lower in children and adolescents with a low-saturated-fat diet since infancy: the special turku coronary risk factor intervention project. Hypertension. 2009;53:918–24.

    Article  PubMed  CAS  Google Scholar 

  69. Pahkala K, Hietalampi H, Laitinen TT, Viikari JS, Ronnemaa T, Niinikoski H, et al. Ideal cardiovascular health in adolescence: effect of lifestyle intervention and association with vascular intima-media thickness and elasticity (the STRIP Study). Circulation. 2013;127(21):2088–96.

    Google Scholar 

  70. Lloyd-Jones DM, Hong Y, Labarthe D, Mozaffarian D, Appel LJ, Van Horn L, et al. Defining and setting national goals for cardiovascular health promotion and disease reduction: the American Heart Association's strategic Impact Goal through 2020 and beyond. Circulation. 2010;121:586–613.

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

Sally Sultan has received grant support from NIH (T32-NS07153).

Compliance with Ethics Guidelines

Conflict of Interest

Sally Sultan declares that she has no conflict of interest. Mitchell S. V. Elkind serves as a consultant to Jarvik Heart, BMS-Pfizer Pharmaceutical Partnership, and Biogen IDEC; receives research support from diaDexus, Inc., Bristol-Myers Squibb/Sanofi Pharmaceuticals Partnership, and the NIH/NINDS and NHLBI; and has given expert testimony on behalf of Novartis, Organon/Merck, and GlaxoSmithKline. He serves as Resident and Fellow Section Editor of Neurology, for which he receives compensation from the American Academy of Neurology. He is also a board member of the American Heart Association/American Stroke Association Founders Affiliate and New York City Boards, for which he receives no payment.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sally Sultan.

Additional information

This article is part of the Topical Collection on Stroke

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sultan, S., Elkind, M.S.V. The Growing Problem of Stroke among Young Adults. Curr Cardiol Rep 15, 421 (2013). https://doi.org/10.1007/s11886-013-0421-z

Download citation

  • Published:

  • DOI: https://doi.org/10.1007/s11886-013-0421-z

Keywords

Navigation