Skip to main content

Advertisement

Log in

Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Sleeve Gastrectomy to Treat Morbid Obesity-Related Comorbidities: a Systematic Review and Meta-analysis

  • Review Article
  • Published:
Obesity Surgery Aims and scope Submit manuscript

Abstract

Our aim was to compare laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) for treating morbid obesity and its related comorbidities. An electronic literature search was performed from inception to May 2015 and a total of 18,455 patients, enrolled in 62 recent studies, were included in this meta-analysis. Patients receiving LRYGB had a significantly higher percentage of excess weight loss and better resolution of hypertension, dyslipidemia, gastroesophageal reflux disease, and arthritis compared with those receiving LSG. LRYGB and LSG showed similar effects on type 2 diabetes mellitus and sleep apnea.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11

Similar content being viewed by others

References

  1. McMichael AJ, Powles JW, Butler CD, et al. Food, livestock production, energy, climate change, and health. Lancet. 2007;370(9594):1253–63. PMID: 17868818.

    Article  PubMed  Google Scholar 

  2. Flegal KM, Kit BK, Orpana H, et al. Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis. JAMA. 2013;309(1):71–82. PMID: 23280227.

    Article  PubMed  CAS  Google Scholar 

  3. Grieve E, Fenwick E, Yang HC, et al. The disproportionate economic burden associated with severe and complicated obesity: a systematic review. Obes Rev. 2013;14(11):883–94. PMID: 23859626, Epub 2013 Jul 16.

    Article  PubMed  CAS  Google Scholar 

  4. Sundbom M. Laparoscopic revolution in bariatric surgery. World J Gastroenterol. 2014;20(41):15135–43. PubMed PMID: 25386062.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Suter M, Donadini A, Romy S, et al. Laparoscopic Roux-en-Y gastric bypass: significant long-term weight loss, improvement of obesity-related comorbidities and quality of life. Ann Surg. 2011;254(2):267–73. PubMed PMID: 21772127.

    Article  PubMed  Google Scholar 

  6. Kueper MA, Kramer KM, Kirschniak A, et al. Laparoscopic sleeve gastrectomy: standardized technique of a potential stand-alone bariatric procedure in morbidly obese patients. World J Surg. 2008;32(7):1462–5. PubMed PMID: 18368447.

    Article  PubMed  Google Scholar 

  7. Gagner M, Deitel M, Kalberer TL, et al. The Second International Consensus Summit for Sleeve Gastrectomy, March 19–21, 2009. Surg Obes Relat Dis. 2009;5(4):476–85. PubMed PMID: 19632647.

    Article  PubMed  Google Scholar 

  8. Hutter MM, Schirmer BD, Jones DB, et al. First report from the American College of Surgeons Bariatric Surgery Center Network: laparoscopic sleeve gastrectomy has morbidity and effectiveness positioned between the band and the bypass. Ann Surg. 2011;254(3):410–20. PubMed PMID: 21865942, discussion 20–2.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Cutolo PP, Nosso G, Vitolo G, et al. Clinical efficacy of laparoscopic sleeve gastrectomy vs laparoscopic gastric bypass in obese type 2 diabetic patients: a retrospective comparison. Obes Surg. 2012;22(10):1535–9. PubMed PMID: 22960950.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  10. Iannelli A, Anty R, Schneck AS, et al. Inflammation, insulin resistance, lipid disturbances, anthropometrics, and metabolic syndrome in morbidly obese patients: a case control study comparing laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy. Surgery. 2011;149(3):364–70. PubMed PMID: 20932542.

    Article  PubMed  Google Scholar 

  11. Boza C, Gamboa C, Salinas J, et al. Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy: a case–control study and 3 years of follow-up. Surg Obes Relat Dis. 2012;8(3):243–9. PubMed PMID: 22285881.

    Article  PubMed  Google Scholar 

  12. Benaiges D, Goday A, Ramon JM, et al. Laparoscopic sleeve gastrectomy and laparoscopic gastric bypass are equally effective for reduction of cardiovascular risk in severely obese patients at one year of follow-up. Surg Obes Relat Dis. 2011;7(5):575–80. PubMed PMID: 21546321.

    Article  PubMed  Google Scholar 

  13. Abbatini F, Rizzello M, Casella G, et al. Long-term effects of laparoscopic sleeve gastrectomy, gastric bypass, and adjustable gastric banding on type 2 diabetes. Surg Endosc. 2010;24(5):1005–10. PubMed PMID: 19866235.

    Article  PubMed  CAS  Google Scholar 

  14. Kehagias I, Karamanakos SN, Argentou M, et al. Randomized clinical trial of laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for the management of patients with BMI < 50 kg/m2. Obes Surg. 2011;21(11):1650–6. PubMed PMID: 21818647.

    Article  PubMed  Google Scholar 

  15. Kasama K, Tagaya N, Kanahira E, et al. Has laparoscopic bariatric surgery been accepted in Japan? The experience of a single surgeon. Obes Surg. 2008;18(11):1473–8. PubMed PMID: 18398667.

    Article  PubMed  Google Scholar 

  16. Vidal P, Ramon JM, Goday A, et al. Laparoscopic gastric bypass versus laparoscopic sleeve gastrectomy as a definitive surgical procedure for morbid obesity. Mid-term results. Obes Surg. 2013;23(3):292–9. PubMed PMID: 23196992.

    Article  PubMed  Google Scholar 

  17. Paluszkiewicz R, Kalinowski P, Wroblewski T, Bartoszewicz Z, Bialobrzeska-Paluszkiewicz J, Ziarkiewicz-Wroblewska B, et al. Prospective randomized clinical trial of laparoscopic sleeve gastrectomy versus open Roux-en-Y gastric bypass for the management of patients with morbid obesity. Wideochirurgia i inne techniki malo inwazyjne = Videosurgery and other miniinvasive techniques / kwartalnik pod patronatem Sekcji Wideochirurgii TChP oraz Sekcji Chirurgii Bariatrycznej TChP. 2012 Dec;7(4):225–32. PubMed PMID: 23362420

  18. Zhang N, Maffei A, Cerabona T, et al. Reduction in obesity-related comorbidities: is gastric bypass better than sleeve gastrectomy? Surg Endosc. 2013;27(4):1273–80. PubMed PMID: 23239292.

    Article  PubMed  Google Scholar 

  19. Lakdawala MA, Bhasker A, Mulchandani D, et al. Comparison between the results of laparoscopic sleeve gastrectomy and laparoscopic Roux-en-Y gastric bypass in the Indian population: a retrospective 1 year study. Obes Surg. 2010;20(1):1–6. PubMed PMID: 19802646.

    Article  PubMed  Google Scholar 

  20. Chouillard EK, Karaa A, Elkhoury M, et al. Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for morbid obesity: case–control study. Surg Obes Relat Dis. 2011;7(4):500–5. PubMed PMID: 21459682.

    Article  PubMed  Google Scholar 

  21. Leyba JL, Aulestia SN, Llopis SN. Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for the treatment of morbid obesity. A prospective study of 117 patients. Obes Surg. 2011;21(2):212–6. PubMed PMID: 20835778.

    Article  PubMed  Google Scholar 

  22. Yaghoubian A, Tolan A, Stabile BE, et al. Laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy achieve comparable weight loss at 1 year. Am Surg. 2012;78(12):1325–8. PubMed PMID: 23265120.

    PubMed  Google Scholar 

  23. Mohos E, Schmaldienst E, Prager M. Quality of life parameters, weight change and improvement of co-morbidities after laparoscopic Roux Y gastric bypass and laparoscopic gastric sleeve resection—comparative study. Obes Surg. 2011;21(3):288–94. PubMed PMID: 20628831.

    Article  PubMed  Google Scholar 

  24. Nocca D, Guillaume F, Noel P, et al. Impact of laparoscopic sleeve gastrectomy and laparoscopic gastric bypass on HbA1c blood level and pharmacological treatment of type 2 diabetes mellitus in severe or morbidly obese patients. Results of a multicenter prospective study at 1 year. Obes Surg. 2011;21(6):738–43. PubMed PMID: 21468625.

    Article  PubMed  Google Scholar 

  25. Benedix F, Westphal S, Patschke R, et al. Weight loss and changes in salivary ghrelin and adiponectin: comparison between sleeve gastrectomy and Roux-en-Y gastric bypass and gastric banding. Obes Surg. 2011;21(5):616–24. PubMed PMID: 21331503.

    Article  PubMed  Google Scholar 

  26. Robert M, Ferrand-Gaillard C, Disse E, et al. Predictive factors of type 2 diabetes remission 1 year after bariatric surgery: impact of surgical techniques. Obes Surg. 2013;23(6):770–5. PubMed PMID: 23355293.

    Article  PubMed  CAS  Google Scholar 

  27. Nelson D, Porta R, Blair K, et al. The duodenal switch for morbid obesity: modification of cardiovascular risk markers compared with standard bariatric surgeries. Am J Surg. 2012;203(5):603–8. PubMed PMID: 22405918.

    Article  PubMed  Google Scholar 

  28. Jimenez A, Casamitjana R, Flores L, et al. Long-term effects of sleeve gastrectomy and Roux-en-Y gastric bypass surgery on type 2 diabetes mellitus in morbidly obese subjects. Ann Surg. 2012;256(6):1023–9. PubMed PMID: 22968072.

    Article  PubMed  Google Scholar 

  29. Karamanakos SN, Vagenas K, Kalfarentzos F, et al. Weight loss, appetite suppression, and changes in fasting and postprandial ghrelin and peptide-YY levels after Roux-en-Y gastric bypass and sleeve gastrectomy: a prospective, double blind study. Ann Surg. 2008;247(3):401–7. PubMed PMID: 18376181.

    Article  PubMed  Google Scholar 

  30. Lim DM, Taller J, Bertucci W, et al. Comparison of laparoscopic sleeve gastrectomy to laparoscopic Roux-en-Y gastric bypass for morbid obesity in a military institution. Surg Obes Relat Dis. 2014;10(2):269–76. PubMed PMID: 23273712.

    Article  PubMed  Google Scholar 

  31. Vix M, Diana M, Liu KH, et al. Evolution of glycolipid profile after sleeve gastrectomy vs. Roux-en-Y gastric bypass: results of a prospective randomized clinical trial. Obes Surg. 2013;23(5):613–21. PubMed PMID: 23207829.

    Article  PubMed  Google Scholar 

  32. Li VK, Pulido N, Fajnwaks P, et al. Predictors of gallstone formation after bariatric surgery: a multivariate analysis of risk factors comparing gastric bypass, gastric banding, and sleeve gastrectomy. Surg Endosc. 2009;23(7):1640–4. PubMed PMID: 19057954.

    Article  PubMed  Google Scholar 

  33. de Gordejuela AG, Pujol Gebelli J, Garcia NV, et al. Is sleeve gastrectomy as effective as gastric bypass for remission of type 2 diabetes in morbidly obese patients? Surg Obes Relat Dis. 2011;7(4):506–9. PubMed PMID: 21411376.

    Article  PubMed  Google Scholar 

  34. Strain GW, Gagner M, Pomp A, et al. Comparison of weight loss and body composition changes with four surgical procedures. Surg Obes Relat Dis. 2009;5(5):582–7. PubMed PMID: 19560983.

    Article  PubMed  Google Scholar 

  35. Ramon JM, Salvans S, Crous X, et al. Effect of Roux-en-Y gastric bypass vs sleeve gastrectomy on glucose and gut hormones: a prospective randomised trial. J Gastrointest Surg. 2012;16(6):1116–22. PubMed PMID: 22402955.

    Article  PubMed  Google Scholar 

  36. Gehrer S, Kern B, Peters T, et al. Fewer nutrient deficiencies after laparoscopic sleeve gastrectomy (LSG) than after laparoscopic Roux-Y-gastric bypass (LRYGB)—a prospective study. Obes Surg. 2010;20(4):447–53. PubMed PMID: 20101473.

    Article  PubMed  Google Scholar 

  37. Overs SE, Freeman RA, Zarshenas N, et al. Food tolerance and gastrointestinal quality of life following three bariatric procedures: adjustable gastric banding, Roux-en-Y gastric bypass, and sleeve gastrectomy. Obes Surg. 2012;22(4):536–43. PubMed PMID: 22170392.

    Article  PubMed  Google Scholar 

  38. Ruz M, Carrasco F, Rojas P, et al. Heme- and nonheme-iron absorption and iron status 12 mo after sleeve gastrectomy and Roux-en-Y gastric bypass in morbidly obese women. Am J Clin Nutr. 2012;96(4):810–7. PubMed PMID: 22952172.

    Article  PubMed  CAS  Google Scholar 

  39. Woelnerhanssen B, Peterli R, Steinert RE, et al. Effects of postbariatric surgery weight loss on adipokines and metabolic parameters: comparison of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy—a prospective randomized trial. Surg Obes Relat Dis. 2011;7(5):561–8. PubMed PMID: 21429816.

    Article  PubMed  Google Scholar 

  40. Benaiges D, Flores-Le-Roux JA, Pedro-Botet J, et al. Impact of restrictive (sleeve gastrectomy) vs hybrid bariatric surgery (Roux-en-Y gastric bypass) on lipid profile. Obes Surg. 2012;22(8):1268–75. PubMed PMID: 22544352.

    Article  PubMed  CAS  Google Scholar 

  41. Romero F, Nicolau J, Flores L, et al. Comparable early changes in gastrointestinal hormones after sleeve gastrectomy and Roux-En-Y gastric bypass surgery for morbidly obese type 2 diabetic subjects. Surg Endosc. 2012;26(8):2231–9. PubMed PMID: 22302537.

    Article  PubMed  Google Scholar 

  42. Topart P, Becouarn G, Ritz P. Comparative early outcomes of three laparoscopic bariatric procedures: sleeve gastrectomy, Roux-en-Y gastric bypass, and biliopancreatic diversion with duodenal switch. Surg Obes Relat Dis. 2012;8(3):250–4. PubMed PMID: 21803660.

    Article  PubMed  Google Scholar 

  43. Bayham BE, Greenway FL, Bellanger DE, et al. Early resolution of type 2 diabetes seen after Roux-en-Y gastric bypass and vertical sleeve gastrectomy. Diabetes Technol Ther. 2012;14(1):30–4. PubMed PMID: 21933001.

    Article  PubMed  Google Scholar 

  44. de la Matta-Martin M, Acosta-Martinez J, Morales-Conde S, et al. Perioperative morbi-mortality associated with bariatric surgery: from systematic biliopancreatic diversion to a tailored laparoscopic gastric bypass or sleeve gastrectomy approach. Obes Surg. 2012;22(7):1001–7. PubMed PMID: 22527597.

    Article  PubMed  Google Scholar 

  45. Peterli R, Borbely Y, Kern B, et al. Early results of the Swiss Multicentre Bypass or Sleeve Study (SM-BOSS): a prospective randomized trial comparing laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass. Ann Surg. 2013;258(5):690–4. PubMed Pubmed Central PMCID: PMC3888472, discussion 5.

    Article  PubMed  PubMed Central  Google Scholar 

  46. Keidar A, Hershkop KJ, Marko L, et al. Roux-en-Y gastric bypass vs sleeve gastrectomy for obese patients with type 2 diabetes: a randomised trial. Diabetologia. 2013;56(9):1914–8. PubMed PMID: 23765186.

    Article  PubMed  Google Scholar 

  47. Zhang Y, Zhao H, Cao Z, et al. A randomized clinical trial of laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy for the treatment of morbid obesity in China: a 5-year outcome. Obes Surg. 2014;24(10):1617–24. PubMed PMID: 24827405.

    Article  PubMed  Google Scholar 

  48. Helmio M, Victorzon M, Ovaska J, et al. Comparison of short-term outcome of laparoscopic sleeve gastrectomy and gastric bypass in the treatment of morbid obesity: a prospective randomized controlled multicenter SLEEVEPASS study with 6-month follow-up. Scand J Surg. 2014;103(3):175–81. PubMed PMID: 24522349.

    Article  PubMed  CAS  Google Scholar 

  49. Vix M, Liu KH, Diana M, et al. Impact of Roux-en-Y gastric bypass versus sleeve gastrectomy on vitamin D metabolism: short-term results from a prospective randomized clinical trial. Surg Endosc. 2014;28(3):821–6. PubMed PMID: 24196556.

    Article  PubMed  Google Scholar 

  50. Leyba JL, Llopis SN, Aulestia SN. Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for the treatment of morbid obesity. A prospective study with 5 years of follow-up. Obes Surg. 2014;24(12):2094–8. PubMed PMID: 25012769.

    Article  PubMed  Google Scholar 

  51. Moore CE, Sherman V. Vitamin D supplementation efficacy: sleeve gastrectomy versus gastric bypass surgery. Obes Surg. 2014;24(12):2055–60. PubMed PMID: 24748475.

    Article  PubMed  Google Scholar 

  52. El Chaar M, Hammoud N, Ezeji G, et al. Laparoscopic sleeve gastrectomy versus laparoscopic Roux-en-Y gastric bypass: a single center experience with 2 years follow-up. Obes Surg. 2015;25(2):254–62. PubMed PMID: 25085223.

    Article  PubMed  Google Scholar 

  53. Dogan K, Gadiot RP, Aarts EO, Betzel B, van Laarhoven CJ, Biter LU, et al. Effectiveness and Safety of Sleeve Gastrectomy, Gastric Bypass, and Adjustable Gastric Banding in Morbidly Obese Patients: a Multicenter, Retrospective, Matched Cohort Study. Obesity surgery. 2014 Nov 19. PubMed PMID: 25408433.

  54. Lee WJ, Chen CY, Ser KH, et al. Differential influences of gastric bypass and sleeve gastrectomy on plasma nesfatin-1 and obestatin levels in patients with type 2 diabetes mellitus. Curr Pharm Des. 2013;19(32):5830–5. PubMed PMID: 23768444.

    Article  PubMed  CAS  Google Scholar 

  55. Bonner GL, Nagy AJ, Jupiter DC, et al. A comparison of postoperative effects of bariatric surgery on medical markers of morbidity. Am J Surg. 2014;208(6):897–902. PubMed PMID: 25440477, discussion 1–2.

    Article  PubMed  Google Scholar 

  56. Alexandrou A, Armeni E, Kouskouni E, et al. Cross-sectional long-term micronutrient deficiencies after sleeve gastrectomy versus Roux-en-Y gastric bypass: a pilot study. Surg Obes Relat Dis. 2014;10(2):262–8. PubMed PMID: 24182446.

    Article  PubMed  Google Scholar 

  57. Zerrweck C, Sepulveda EM, Maydon HG, et al. Laparoscopic gastric bypass vs. sleeve gastrectomy in the super obese patient: early outcomes of an observational study. Obes Surg. 2014;24(5):712–7. PubMed PMID: 24352748.

    Article  PubMed  Google Scholar 

  58. Carrasco F, Basfi-Fer K, Rojas P, et al. Changes in bone mineral density after sleeve gastrectomy or gastric bypass: relationships with variations in vitamin D, ghrelin, and adiponectin levels. Obes Surg. 2014;24(6):877–84. PubMed PMID: 24435517.

    Article  PubMed  Google Scholar 

  59. Lancha A, Moncada R, Valenti V, et al. Comparative effects of gastric bypass and sleeve gastrectomy on plasma osteopontin concentrations in humans. Surg Endosc. 2014;28(8):2412–20. PubMed PMID: 24622764.

    Article  PubMed  Google Scholar 

  60. Yousseif A, Emmanuel J, Karra E, et al. Differential effects of laparoscopic sleeve gastrectomy and laparoscopic gastric bypass on appetite, circulating acyl-ghrelin, peptide YY3-36 and active GLP-1 levels in non-diabetic humans. Obes Surg. 2014;24(2):241–52. PubMed PMID: 23996294.

    Article  PubMed  PubMed Central  Google Scholar 

  61. Iannelli A, Anty R, Schneck AS, et al. Evolution of low-grade systemic inflammation, insulin resistance, anthropometrics, resting energy expenditure and metabolic syndrome after bariatric surgery: a comparative study between gastric bypass and sleeve gastrectomy. J Visc Surg. 2013;150(4):269–75. PubMed PMID: 24016714.

    Article  PubMed  CAS  Google Scholar 

  62. Coupaye M, Riviere P, Breuil MC, et al. Comparison of nutritional status during the first year after sleeve gastrectomy and Roux-en-Y gastric bypass. Obes Surg. 2014;24(2):276–83. PubMed PMID: 24122661.

    Article  PubMed  Google Scholar 

  63. Nannipieri M, Baldi S, Mari A, et al. Roux-en-Y gastric bypass and sleeve gastrectomy: mechanisms of diabetes remission and role of gut hormones. J Clin Endocrinol Metab. 2013;98(11):4391–9. PubMed PMID: 24057293.

    Article  PubMed  CAS  Google Scholar 

  64. Albeladi B, Bourbao-Tournois C, Huten N. Short- and midterm results between laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy for the treatment of morbid obesity. J Obes. 2013;2013:934653. PubMed PMID: 24078867.

    Article  PubMed  PubMed Central  Google Scholar 

  65. Kosanovic R, Romero RJ, Donkor C, et al. A comparative retrospective study of robotic sleeve gastrectomy vs robotic gastric bypass. Int J Med Robot. 2014. Doi: 10.1002/rcs.1621. PubMed PMID: 25417602

  66. Carlin AM, Zeni TM, English WJ, et al. The comparative effectiveness of sleeve gastrectomy, gastric bypass, and adjustable gastric banding procedures for the treatment of morbid obesity. Ann Surg. 2013;257(5):791–7. PubMed PMID: 23470577.

    Article  PubMed  Google Scholar 

  67. Vilarrasa N, de Gordejuela AG, Gomez-Vaquero C, et al. Effect of bariatric surgery on bone mineral density: comparison of gastric bypass and sleeve gastrectomy. Obes Surg. 2013;23(12):2086–91. PubMed PMID: 23818239.

    Article  PubMed  Google Scholar 

  68. Viana EC, Araujo-Dasilio KL, Miguel GP, et al. Gastric bypass and sleeve gastrectomy: the same impact on IL-6 and TNF-alpha. Prospective clinical trial. Obes Surg. 2013;23(8):1252–61. PubMed PMID: 23475776.

    Article  PubMed  Google Scholar 

  69. Terra X, Auguet T, Guiu-Jurado E, et al. Long-term changes in leptin, chemerin and ghrelin levels following different bariatric surgery procedures: Roux-en-Y gastric bypass and sleeve gastrectomy. Obes Surg. 2013;23(11):1790–8. PubMed PMID: 23832521.

    Article  PubMed  Google Scholar 

  70. Weiner RA, El-Sayes IA, Theodoridou S, et al. Early post-operative complications: incidence, management, and impact on length of hospital stay. A retrospective comparison between laparoscopic gastric bypass and sleeve gastrectomy. Obes Surg. 2013;23(12):2004–12. PubMed PMID: 23846474.

    Article  PubMed  Google Scholar 

  71. Hurt RT, Edakkanambeth Varavil J, Ebbert JO. New pharmacological treatments for the management of obesity. Curr Gastroenterol Rep. 2014;16(6):394. PMID: 24828101.

    Article  PubMed  Google Scholar 

  72. Boido A, Ceriani V, Cetta F, et al. Bariatric surgery and prevention of cardiovascular events and mortality in morbid obesity: mechanisms of action and choice of surgery. Nutr Metab Cardiovasc Dis. 2015;25(5):437–43. PMID: 25770762, Epub 2015 Feb 7.

    Article  PubMed  CAS  Google Scholar 

  73. Frühbeck G. Bariatric and metabolic surgery: a shift in eligibility and success criteria. Nat Rev Endocrinol. 2015;11(8):465–77. PMID: 26055046, Epub 2015 Jun 9.

    Article  PubMed  Google Scholar 

  74. Rubino F, Kaplan LM, Schauer PR, et al. The Diabetes Surgery Summit consensus conference: recommendations for the evaluation and use of gastrointestinal surgery to treat type 2 diabetes mellitus. Ann Surg. 2010;251(3):399–405. PMID: 19934752.

    Article  PubMed  Google Scholar 

  75. Ochner CN, Gibson C, Shanik M, et al. Changes in neurohormonal gut peptides following bariatric surgery. Int J Obes (Lond). 2011;35(2):153–66. PubMed PMID: 20625384

  76. Sarkhosh K, Birch DW, Shi X, et al. The impact of sleeve gastrectomy on hypertension: a systematic review. Obes Surg. 2012;22(5):832–7. PubMed PMID: 22350987.

    Article  PubMed  Google Scholar 

  77. Kotchen TA. Obesity-related hypertension: epidemiology, pathophysiology, and clinical management. Am J Hypertens. 2010;23(11):1170–8. PubMed PMID: 20706196.

    Article  PubMed  CAS  Google Scholar 

  78. Young T, Peppard PE, Taheri S. Excess weight and sleep-disordered breathing. J Appl Physiol 2005;99(4):1592–9. PubMed PMID: 16160020

  79. Bassi M, Furuya WI, Zoccal DB, et al. Control of respiratory and cardiovascular functions by leptin. Life Sci. 2015; 125:25–31. Epub 2015 Jan 30. PMID: 25645056

  80. Campo A, Frühbeck G, Zulueta JJ, et al. Hyperleptinaemia, respiratory drive and hypercapnic response in obese patients. Eur Respir J. 2007;30(2):223–31. PMID: 17459895, Epub 2007 Apr 25.

    Article  PubMed  CAS  Google Scholar 

  81. Chopra A, Chao E, Etkin Y, et al. Laparoscopic sleeve gastrectomy for obesity: can it be considered a definitive procedure? Surg Endosc. 2012;26(3):831–7. PubMed PMID: 22179438.

    Article  PubMed  Google Scholar 

  82. Yehoshua RT, Eidelman LA, Stein M, et al. Laparoscopic sleeve gastrectomy—volume and pressure assessment. Obes Surg. 2008;18(9):1083–8. PubMed PMID: 18535864.

    Article  PubMed  Google Scholar 

  83. Keidar A, Appelbaum L, Schweiger C, et al. Dilated upper sleeve can be associated with severe postoperative gastroesophageal dysmotility and reflux. Obes Surg. 2010;20(2):140–7. PubMed PMID: 19949885.

    Article  PubMed  Google Scholar 

  84. Li JF, Lai DD, Lin ZH, et al. Comparison of the long-term results of Roux-en-Y gastric bypass and sleeve gastrectomy for morbid obesity: a systematic review and meta-analysis of randomized and nonrandomized trials. Surg Laparosc Endosc Percutan Tech. 2014;24(1):1–11. PubMed PMID: 24487151.

    Article  PubMed  Google Scholar 

  85. Bairdain S, Samnaliev M. Cost-effectiveness of adolescent bariatric surgery. Cureus. 2015;7(2), e248. PMID: 26180672.

    PubMed  Google Scholar 

Download references

Funding

No funding supported

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jianfang Li.

Ethics declarations

Conflicts of Interest

Jianfang Li, Dandan Lai, and Dongping Wu declare that they have no conflict of interest.

Ethical Approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Li, J., Lai, D. & Wu, D. Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Sleeve Gastrectomy to Treat Morbid Obesity-Related Comorbidities: a Systematic Review and Meta-analysis. OBES SURG 26, 429–442 (2016). https://doi.org/10.1007/s11695-015-1996-9

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11695-015-1996-9

Keywords

Navigation