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Musculoskeletal rehabilitation after hip fracture: a review

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Abstract

Summary

This review article on musculoskeletal rehabilitation after hip fractures summarizes current scientific evidence concerning prevention, treatment and post-fracture surveillance of patients who sustained a low-trauma hip fracture due to osteoporosis.

Introduction

With increasing longevity, hip fractures become more and more a serious burden not only for societies in developed civilization, but also for emerging countries. According to world-wide projections 1.5 million people are affected each year. Although a lot of research has been performed over the last decade, there is still a lack of standardized and evidence-based approaches for prevention, treatment and rehabilitation of this worst complication of osteoporosis. Therefore, the evidence base for this article was synthesized in accordance with SIGN methodology. Databases searched include Medline, Embase, CINAHL and the Cochrane Library between January 1996 and March 2010. The following terms are used: osteoporosis, hip fracture, rehabilitation, falls, muscle strength, nutrition, exercise, balance, sway, and hip protectors. Moreover, reference lists from included studies were checked and author’s names were searched for additional studies. Possibly, the best approach to rehabilitation after hip fracture is a multi-disciplinary team co-ordinating medical, social, educational and vocational measure for training or retraining the individual to the highest possible level of function. In order to prevent thromboembolism fondaparinux should be used for 28 days starting 6 h after surgery. This should be accompanied by a daily nutritional intake of at least 20-g protein, 1,200 mg of elemental calcium and 800 IU of vitamin D; whereas in severe vitamin D insufficiencies, recommendations may be certainly higher. After surgical repair of the hip fracture, an anti-resorptive medication should be started. While balance training and performing of Tai Chi has been shown to reduce fall risk and thereby also decrease hip fracture risk, the use of hip protectors is still under evaluation and cannot be generally advocated.

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References

  1. Mangione KK, Craik RL, Tomlinson SS, Palombaro KM (2005) Can elderly patients who have had a hip fracture perform moderate- to high-intensity exercise at home? Phys Ther 85:727–739

    PubMed  Google Scholar 

  2. Office of the Surgeon General Bone Health and Osteoporosis (2004) A Report of the Surgeon General. United States Department of Health and Human Services. pp. 6–8

  3. Mossey JM, Mutran E, Knott K, Craik R (1989) Determinants of recovery 12 months after hip fracture: the importance of psychosocial factors. Am J Public Health 72:279–286

    Article  Google Scholar 

  4. Haentjens P, Magaziner J, Colon-Emeric CS, Vanderschueren D, Milisen K, Velkeniers B, Boonen S (2010) Meta-analysis: excess mortality after hip fracture among older women and men. Ann Intern Med 152:380–390

    PubMed  Google Scholar 

  5. Marotolli RA, Berkman LF, Cooney LM (1992) Decline in physical function following hip fracture. J Am Geriatr Soc 40:861–866

    Google Scholar 

  6. Zuckerman JD, Koval KJ, Aharonoff GB, Skovren ML (2000) A functional recovery score for elderly hip fracture patients: validity and reliability. J Orthop Trauma 14:26–30

    Article  CAS  PubMed  Google Scholar 

  7. Jakobsen SJ, Goldberg J, Miles TP, Brody JA, Stiers W, Rimm AA (1990) Hip fracture incidence among the old and very old: a population-based study of 745, 435 cases. Am J Public Health 80:871–873

    Article  Google Scholar 

  8. Tolo ET, Bostrom MP, Simic PM, Lyden JP, Cornell CM, Thorngren KG (1999) The short term outcome of elderly patients with hip fractures. Int Orthop 23:279–282

    Article  CAS  PubMed  Google Scholar 

  9. Norton R, Butler M, Robinson E, Lee-Joe T, Campbell AJ (2000) Declines in physical functioning attributable to hip fracture among older people: a follow-up study of case-control participants. Disabil Rehabil 22:345–351

    Article  CAS  PubMed  Google Scholar 

  10. Scottish Intercollegiate Guidelines Network (SIGN) (2009) Management of Hip Fracture in Older People. Edinburgh 2009, (SIGN publication) no. 111. Available at: www.sign.ac.uk/pdf/sign104.pdf. Accessed 30 September 2010

  11. Jensen CS, Mak CID, March LM (2010) Evidence-based guidelines for the management of hip fractures in older persons: an update. Med J Aust 192:37–41

    Google Scholar 

  12. Rucco V, Visentini A, Pellegrini E (2003) The rehabilitation project in hip arthroplasty patients. Eur Med Phys 39:45–57

    Google Scholar 

  13. Dionyssiotis Y, Dontas IA, Economopoulos D, Lyritis GP (2008) Rehabilitation after falls and fractures. J Musculoskelet Neuronal Interact 8:244–250

    CAS  PubMed  Google Scholar 

  14. Pfeifer M, Sinaki M, Geusens P, Boonen S, Preisinger E, Minne HW for the ASBMR Working Group on Musculoskeletal Rehabilitation (2004) Musculoskeletal rehabilitation of osteoporosis: a review. J Bone Miner Res 19:1208–1214

    Article  Google Scholar 

  15. NHS Quality improvement Scotland. Anaesthesia (2003) Care Before and After Anaesthesia. NHS QIS; 2003. Available at: http://www.nhshealthquality.org/nhsqis/controller?p_service=Content.show&p_applic=CCC&pContentID=3445. Accessed 20 September 2010

  16. Rosenberg J, Pedersen MH, Gebuhr P, Kehlet H (1992) Effect of oxygen therapy on late postoperative episodic and constant hypoxemia. Br J Anaesth 68:146–150

    Article  Google Scholar 

  17. Royal College of Physicians (1989) Fractured neck of femur. Prevention and management. Summary and recommendations of the Royal Cord of Physicians. J R Coll Physicians Lond 23:8–12

    Google Scholar 

  18. Parker MJ (2000) Evidence based case report: managing an elderly patient with a fractured femur. BMJ 320:102–103

    Article  CAS  PubMed  Google Scholar 

  19. Watson JE (1997) Watsons clinical nursing and related sciences, 5th edn. Bailliere Tindall, London

    Google Scholar 

  20. Anemell A, Handoll HHG (2006) Nutritional supplementation for hip fracture aftercare in older people. Cochrane Databaseof Systematic Reviews Issue 4. Art. No: CD001880. doi:10.1002/14651858. CD001880.pub4

  21. O’Cathin A (1994) Evaluation of a hospital at home scheme for the early discharge of patients with fractures neck of femur. J Public Health Med 16:205–210

    Google Scholar 

  22. Parker MJ, Pryor GA, Myles JW (1991) Early discharge after hip fracture. Prospective 3-year study of 645 patients. Acta Orthop Scand 62:563–566

    Article  CAS  PubMed  Google Scholar 

  23. Cameron I, Lyle D, Quine S (1993) Accelerated rehabilitation after proximal femoral fracture: a randomized controlled trial. Disabil Rehabil 15:29–34

    Article  CAS  PubMed  Google Scholar 

  24. Tierny A, Vallis J (1999) Multidisciplinary team working in the care of elderly patients with hip fracture. J Interprof Care 13:41–52

    Article  Google Scholar 

  25. Ensberg M, Paletta J, Galecki A, Dacko C, Fries B (1993) Identifying elderly patients for early discharge after hospitalisation for hip fracture. J Gerontol A Biol Sci Med Sci 48:187–194

    Google Scholar 

  26. Fox K, Hawkes W, Hebel J, Felsenthal G, Clark M, Sea Z (1998) Mobility after hip fracture predicts health outcomes. J Am Geriatr Soc 46:169–173

    CAS  PubMed  Google Scholar 

  27. Cameron ID, Crotty M, Currie C, Finnegan T, Gillespie L, Gillespie W (2000) Geriatric rehabilitation following fractures in older people: a systemic review. Health Technol Assess 4(2):1–111

    Google Scholar 

  28. Fiaterone MA, O’Neill EF, Ryan JD, Clements KM, Solares GR, Nelson ME, Roberts SB, Kehayias JJ, Lipsitz LA, Evans WJ (1994) Exercise training and nutrional supplementation for physical frailty in very elderly people. N Engl J Med 330:1769–1775

    Article  Google Scholar 

  29. Mulrow CD, Gerety MB, Kanteln D (1994) A randomized trial of physical rehabilitation for very frail nursing home residents. J Am Med Assoc 271:519–524

    Article  CAS  Google Scholar 

  30. Host HH, Sinacore DR, Bohnert KL, Steger-May K, Brown M, Binder EF (2007) Training-induced strength and functional adaptations after hip fracture. Phys Ther 87:292–303

    Article  PubMed  Google Scholar 

  31. Hauer K, Specht N, Schuler M, Bartsch P, Oster P (2002) Intensive physical training in geriatric patients after severe falls and hip surgery. Age Ageing 31:49–57

    Article  PubMed  Google Scholar 

  32. Binder EF, Brown M, Sinacore DR, Steger-May K, Yarasheski KE, Schechtmann KB (2004) Effects of extended outpatient rehabilitation after hip fracture: a randomized controlled trial. J Am Med Assoc 292:837–846

    Article  CAS  Google Scholar 

  33. Kayali C, Agus H, Ozluk S, Sanli C (2006) Treatment for unstable intertrochanteric fractures in elderly patients: internal fixation versus cone hemiarthropathy. J Orthop Surg 14:240–244

    CAS  Google Scholar 

  34. Mont MA, Tankersley WS, Hungerford DS (1997) In: Rehabilitation Secrets. (eds) Young MA, O`Yang B, Steins SA. Hanley and Belfus, Philadelphia. pp. 330–337

  35. Boonen S, Autier P, Barette M, Vanderschueren D, Lips P, Haentjens P (2004) A 1 year prospective controlled study. Osteoporos Int 15:87–94

    Article  PubMed  Google Scholar 

  36. Lawrence VA, Hilsenbeck SG, Noveck H, Poses RM, Carson JL (2002) Medical complications and outcomes after hip fracture repair. Arch Intern Med 162:2053–2057

    Article  PubMed  Google Scholar 

  37. Thorngren KG (1997) Optimal treatment of hip fractures. Acta Orthop Scand 62:31–34

    Google Scholar 

  38. Cameron ID, Chen JS, March LM, Cumming RG, Seibel MJ, Sambrook PN (2009) Hip fracture causes excess mortality due to cardiovascular and infectious disease in institutionalized older people: a prospective five-year study. J Bone Miner Res 25(4):866–872

    Google Scholar 

  39. Bernadini B, Meinecke C, Pagani M (1995) Co-morbidity and adverse clinical events in the rehabilitation of older adults after hip fracture. J Am Geriatr Soc 43:894–898

    Google Scholar 

  40. Hagsten B, Svensson O, Gardulf A (2006) Health-related quality of life and self-reported ability concerning ADL and IADL after hip fracture: a randomized trial. Acta Orthop 77:114–119

    Article  PubMed  Google Scholar 

  41. Cifu DX (1993) Rehabilitation of the elderly crash victim. In: Retchin S (ed) Geriatric clinics. Saunders, Philadelphia, pp 473–483

    Google Scholar 

  42. MacDonald W, Owen JW (1988) The effect of total hip replacement on driving reactions. J Bone Joint Surg Br 70B:202–205

    Google Scholar 

  43. Kramer AM, Steiner JF, Schlenker RE (1997) Outcomes and costs after hip fracture and stroke: a comparison of rehabilitation settings. J Am Med Assoc 277:396–404

    Article  CAS  Google Scholar 

  44. Kane RL, Chen Q, Blewett LA, Sangl J (1996) Do rehabilitative nursing homes improve the outcome of care? J Am Geriatr Soc 44:545–555

    CAS  PubMed  Google Scholar 

  45. Giaquinto S, Majolo II, Palma E, Roncacci S, Sciarra A, Vittoria E (2000) Very old people can have favourable outcome after hip fracture: 58 patients referred to rehabilitation. Arch Gerontol Geriatr 31:13–18

    Article  PubMed  Google Scholar 

  46. Reid J, Kennie DC (1989) Geriatric rehabilitative care after fractures of the proximal femur: one year follow-up of a randomized clinical trial. Br Med J 299:25–26

    Article  CAS  Google Scholar 

  47. Cameron ID, Handoll HH, Finnegan TP, Madhoc R, Langhorne P (2009) Co-ordinated multi-disciplinary approaches for inpatient rehabilitation of older patients with proximal femoral fractures. Cochrane Database Syst Rev: CD000106.

  48. Tinetti ME, Baker DI, Gottschalk M, Williams CS, Pollack D, Garrett P, Gill TM, Marotolli RA, Acampora D (1999) Home-based multi-component rehabilitation program for older persons after hip fracture. Arch Phys Med Rehabil 80:916–922

    Article  CAS  PubMed  Google Scholar 

  49. Sherrington C, Lord SR (1997) Home exercise to improve strength and walking velocity after hip fractute: a randomized controlled trial. Arch Phys Med Rehabil 78:208–212

    Article  CAS  PubMed  Google Scholar 

  50. Skelton DA, Dinan S, Campbell M, Rutherford O (2005) Tailored group exercise (Falls Management Exercise—FaME) reduces falls in community-dwelling older frequent fallers (an RCT). Age Ageing 34:636–639

    Article  PubMed  Google Scholar 

  51. de Kam D, Smulders E, Weerdesteyn V, Smits-Engelsman BCM (2009) Exercise interventions to reduce fall-related fractures and their risk factors in individuals with low bone density: a systematic review of randomized controlled trial. Osteoporos Int 20:2111–2125

    Article  PubMed  Google Scholar 

  52. Bonaiuti D (2002) Exercise for preventing and treating osteoporosis in postmenopausal women. Cochrane Database Sysr Rev Issue 2. Art. No.: CD000333

  53. Weerdesteyn V, Rijken H, Geurts AC, Smits-Engelman BC, Mulder T, Duysens J (2006) A five-week exercise program can reduce falls and improve obstacle avoidance in the elderly. Gerontology 52:131–141

    Article  PubMed  Google Scholar 

  54. Gillespie LD, Gillespie WJ, Robertson MC, Lamb SE, Cumming RG, Rowe BH (2003) Interventions for preventing falls in elderly people. Cochrane Database Syst Rev: CD000340

  55. Asikainen TM, Kukkonen-Harjula K, Miilunpalo S (2004) Exercise for health for early postmenopausal women: a systemic review of randomized controlled trials. Sports Med 34:753–778

    Article  PubMed  Google Scholar 

  56. Howe TE, Rochester L, Jackson A, Banks PM, Blair VA (2007) Exercise for improving balance in older people. Cochrane Database Syst Rev: CD004963

  57. Malmros B, Mortensen L, Jensen MB, Charles P (1996) Positive effects of physiotherapy on chronic pain and performance in osteoporosis. Osteoporos Int 8:215–221

    Article  Google Scholar 

  58. Sherrington C, Whitney JC, Lord SR, Herbert RD, Cumming RG, Close JC (2008) Effective exercise for the prevention of falls: a meta-analysis of individual-level data. J Am Geriatr Soc 56:2234–2243

    Article  PubMed  Google Scholar 

  59. Korpelainen R, Keinanen-Kiukaanniemi S, Heikkinen J, Vaananen K, Korpelainen J (2006) Effect of exercise on extra-skeletal risk factors for hip fractures in elderly women with low BMD: a population-based randomized controlled trial. J Bone Miner Res 21:772–779

    Article  PubMed  Google Scholar 

  60. Madureira MM, Takayama L, Gallimaro AL, Caparbo VF, Costa RA, Pereira RM (2007) Balance training program is highly effective in improving functional status and reducing the risk of falls in elderly women with osteoporosis: a randomized controlled trial. Osteoporos Int 18:419–425

    Article  CAS  PubMed  Google Scholar 

  61. Maciaszek J, Osinski W, Szeklicki R, Stemplewski R (2007) Effect of Tai Chi on body balance: a randomized controlled trial in men with osteopenia or osteoporosis. Am J Chin Med 35:1–9

    Article  CAS  PubMed  Google Scholar 

  62. Orr R, Raymond J, Fiaterone SM (2008) Efficacy of progressive resistance training on balance performance in older adults: a systematic review of randomized controlled trials. Sports Med 38:317–343

    Article  PubMed  Google Scholar 

  63. Papaioannou A, Adachi JD, Winegard KJ, Ferko N, Parkinson W, Cook RJ, McCartney N (2003) Efficacy of home-based exercise for improving quality of life among elderly women with hip fractures. Osteoporos Int 14:677–682

    Article  CAS  PubMed  Google Scholar 

  64. Liu-Ambrose TY, Khan KM, Eng JJ, Janssen PA, Lord SR, McKay HA (2004) Resistance and agility training reduce fall risk in women aged 75 to 85 with low bone mass: a 6-month randomized, controlled trial. J Am Geriatr Soc 52:657–665

    Article  PubMed  Google Scholar 

  65. Mitchell SL, Grant S, Aitchison T (1998) Physiological effects of exercise on post-menopausal osteoporotic women. Physiotherapy 84:157–163

    Article  Google Scholar 

  66. Albrand G, Munoz F, Sornay-Rendu E, DuBoeuf F, Delmas PD (2003) Independent predictors of all osteoporosis-related fractures in healthy postmenopausal women: the OFELY study. Bone 32:78–85

    Article  CAS  PubMed  Google Scholar 

  67. Nguyen T, Sambrook P, Kelly P, Jones G, Lord SR, Freund J, Eisman J (1993) Prediction of hip fracture risk by postural imstability, quadriceps strength, and bone density. Br Med J 307:1111–1115

    Article  CAS  Google Scholar 

  68. Carter ND, Khan KM, Mallinson A, Janssen PA, Heinonen A, Petit MA, McKay HA (2002) Knee extension strength is a significant determinant of static and dynamic balance as well as quality of life in older community-dwelling women with osteoporosis. Gerontology 48:360–368

    Article  PubMed  Google Scholar 

  69. Swanenburg J, de Bruin ED, Stauffacher M, Mulder T, Uebelhart D (2007) Effects of exercise and nutrition on postural balance and risk of falling in elderly people with decreased bone mineral density: a randomized controlled trial pilot study. Clin Rehabil 21:523–534

    Article  PubMed  Google Scholar 

  70. Bergstrom I, Landgren B, Brinck J, Freyschuss B (2008) Physical training preserves bone mineral density in postmenopausal women with hip fractures and low bone mineral density. Osteoporos Int 19:177–183

    Article  CAS  PubMed  Google Scholar 

  71. Hourigan SR, Nitz JC, Brauer SG, O’Neill S, Wong J, Richardson CA (2008) Positive effects of exercise and falls and fracture risk in postmenopausal women. Osteoporos Int 19:1077–1086

    Article  CAS  PubMed  Google Scholar 

  72. Sinaki M, Brey RH, Hughes CA, Larson DR, Kaufman KR (2005) Balance disorder and increased risk of falls in osteoporosis and kyphosis: significance of kyphotic posture and muscle strength. Osteoporos Int 16:1004–1010

    Article  PubMed  Google Scholar 

  73. Arnold CM, Busch AJ, Schachter CL, Harrison L, Olszymski W (2005) The relationship of intrinsic fall risk factors to a recent history of falling in older women with osteoporosis. J Orthop Sports Phys Ther 35:452–460

    PubMed  Google Scholar 

  74. Pfeifer M, Begerow B, Minne HW (2004) Effects of a newly developed spinal orthosis on posture, trunk muscle strength and quality of life in women with postmenopausal osteoporosis. Am J Phys Med Rehabil 83:177–186

    Article  PubMed  Google Scholar 

  75. Kannus P, Parkkari J, Niemi S, Pasanen M, Palvanen M, Jarvinen M, Vuori I (2000) Prevention of hip fracture in elderly people with use of a hip protector. N Engl J Med 343:1506–1513

    Article  CAS  PubMed  Google Scholar 

  76. Ekman A, Mallmin H, Michaelsson K, Ljunghall S (1997) External hip protectors to prevent osteoporotic hip fractures. Lancet 350:563–564

    Article  CAS  PubMed  Google Scholar 

  77. Harada A, Mizuno M, Takemura M, Tokudo H, Okuizumi H, Nino N (2001) Hip fracture prevention trial using hip protectors in Japanese nursing homes. Osteoporos Int 12:215–221

    Article  CAS  PubMed  Google Scholar 

  78. Lauritzen JB, Petersen MM, Lund B (1993) Effect of external hip protectors on hip fractures. Lancet 341:11–13

    Article  CAS  PubMed  Google Scholar 

  79. van Schoor NM, Smit JH, Twisk JW, Bouter LM, Lips P (2003) Prevention of hip fractures by external hip protectors: a randomized controlled trial. J Am Med Assoc 289:1957–1962

    Article  Google Scholar 

  80. van Schoor NM, Deville WL, Bouter LM, Lips P (2002) Acceptance and compliance with external hip protectors: a systematic review of the literature. Osteoporos Int 13:917–924

    Article  PubMed  Google Scholar 

  81. Kiel DP, Magaziner J, Zimmermann S, Ball L, Barton BA, Brown KM, Stone JP, Dewkett D, Birge SJ (2007) Efficacy of a hip protector to prevent hip fracture in nursing home residents: the HIP PRO randomized controlled trial. J Am Med Assoc 298:413–422

    Article  CAS  Google Scholar 

  82. Parker MJ, Gillespie WJ, Gillespie LD (2006) Effectiveness of hip protectors for preventing hip fractures in elderly people: a systematic review. Br Med J 332:571–574

    Article  Google Scholar 

  83. Cameron ID, Robinovitch S, Birge S, Kannus P, Khan K, Lauritzen J, Howland J, Evans S, Minns J, Laing A, Cripton P, Derler S, Plant D, Kiel DP (2010) Hip protectors: recommendations for conducting clinical trials: an international consensus statement (part II). Osteoporos Int 21:1–10

    Article  CAS  PubMed  Google Scholar 

  84. Jensen JE, Jensen TG, Smith TK, Johnston DA, Dudrick SJ (1982) Nutrition in orthopaedic surgery. J Bone Joint Surg 64:1263–1272

    CAS  PubMed  Google Scholar 

  85. Delmi M, Rapin CH, Bengoa JM, Delmas PD, Vasey H, Bonjour JP (1990) Dietary supplementation in elderly patients with fractured neck of the femur. Lancet 335:1013–1016

    Article  CAS  PubMed  Google Scholar 

  86. Chevalley T, Rizzoli R, Nydegger V, Slosman D, Tkatch L, Rapin CH, Vasey H, Bonjour JP (1991) Preferential low bone mineral density of the femoral neck in patients with a recent fracture of the proximal femur. Osteoporos Int 1:147–154

    Article  CAS  PubMed  Google Scholar 

  87. Geinoz G, Rapin CH, Rizzoli R, Kraemer R, Buchs B, Slosman D, Michel JP, Bonjour JP (1993) Relationship between bone mineral density and dietary intakes in the elderly. Osteoporos Int 3:242–248

    Article  CAS  PubMed  Google Scholar 

  88. Sullivan DH, Patch GA, Walls RC, Lipschitz DA (1990) Impact of nutrition status on morbidity in a select population of geriatric rehabilitation patients. Am J Clin Nutr 51:749–758

    CAS  PubMed  Google Scholar 

  89. Schürch MA, Rizzoli R, Mermillod B, Vasey H, Michel JP, Bonjour JP (1996) A prospective study on socioeconomic aspects of fracture of the proximal femur. J Bone Miner Res 11:1935–1942

    Article  PubMed  Google Scholar 

  90. Tkatch L, Rapin CH, Rizzoli R, Slosman D, Nydegger V, Vasey H, Bonjour JP (1992) Benefits of oral protein supplement in elderly patients with fracture of the proximal femur. J Am Coll Nutr 11:519–525

    CAS  PubMed  Google Scholar 

  91. Schürch MA, Rizzoli R, Slosman D, Vadas L, Vergnaud P, Bonjour JP (1998) Protein supplements increase serum insulin-like growth factor-1 levels and attenuates proximal femur bone loss in patients with recent hip fracture: a randomized, double-blind, placebo-controlled trial. Ann Intern Med 128:801–809

    PubMed  Google Scholar 

  92. Chapuy MC, Arlot ME, Duboeuf F, Brun J, Crouzet B, Arnaud S, Delmas PD, Meunier PJ (1992) Vitamin D3 and calcium to prevent hip fractures in elderly women. N Engl J Med 327:1637–1642

    Article  CAS  PubMed  Google Scholar 

  93. Dawson-Hughes B, Harris SS, Krall EA, Dallal G (1997) Effects of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older. N Engl J Med 337:670–676

    Article  CAS  PubMed  Google Scholar 

  94. Pfeifer M, Minne HW (1998) Vitamin D and hip fracture. Trends Endocrinol Metab 10:417–420

    Google Scholar 

  95. Pfeifer M, Begerow B, Minne HW, Abrams C, Nachtigall D, Hansen C (2000) Effects of a short-term vitamin D and calcium supplementation on body sway and secondary hyperparathyreoidism in elderly women. J Bone Miner Res 15:1113–1118

    Article  CAS  PubMed  Google Scholar 

  96. Bischoff HA, Stähelin HB, Dick W, Akos R, Knecht M, Salis C, Nebiker M, Theiler R, Pfeifer M, Begerow B, Lew RA, Conzelmann M (2003) Effects of vitamin D and calcium supplementation on falls: a randomized controlled trial. J Bone Miner Res 18:343–351

    Article  CAS  PubMed  Google Scholar 

  97. Bischoff-Ferrari HA, Willett WC, Wong JB, Stuck AE, Staehelin HB, Orav EJ, Thoma A, Kiel DP, Henschkowsky J (2009) Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials. Arch Intern Med 169:551–561

    Article  CAS  PubMed  Google Scholar 

  98. Boonen S, Lips P, Bouillon R, Bischoff-Ferrari HA, Vanderschueren D, Haentjens P (2007) Need for additional calcium to reduce the risk of hip fracture with vitamin D supplementation: evidence from a comparative meta-analysis of randomized controlled trials. J Clin Endocrinol Metab 92:1415–1423

    Article  CAS  PubMed  Google Scholar 

  99. Bischoff-Ferrari HA, Dawson-Hughes B, Baron JA, Burckhardt P, Li R, Spiegelman D, Specker B, Orav JE, Wong JB, Staehelin HB, O’Reilly E, Kiel DP, Willett WC (2007) Calcium intake and hip fracture risk in men and women: a meta-analysis of prospective cohort studies and randomized trials. Am J Clin Nutr 86:1780–1790

    CAS  PubMed  Google Scholar 

  100. LeBoff MS, Hawkes WG, Glowacki J, Yu-Yahiro J, Hurwitz S, Magaziner J (2008) Vitamin-D-deficiency and post-fracture changes in lower extremity function and falls in women with hip fracture. Osteoporos Int 19:1283–1290

    Article  CAS  PubMed  Google Scholar 

  101. Papapoulos SE, Quandt SA, Liberman UA, Hochberg MC, Thompson DE (2004) Meta-analysis of the efficacy of alendronate for the prevention of hip fractures in postmenopausal women. Osteoporos Int 15:2–8

    Google Scholar 

  102. McClung MR, Geusens P, Miller PD, Zippel H, Bensen WG, Roux C, Adami S, Fogelman I, Diamond T, Eastell R, Meunier PJ, Reginster JY, Hip Intervention Program Study Group (2001) Effect of risedronate on the risk of hip fracture in elderly women. N Engl J Med 344:333–340

    Article  CAS  PubMed  Google Scholar 

  103. Lyles KW, Colon-Emeric CS, Magaziner JS, Adachi JD, Pieper CF, Mautalen C, Hylstrup L, Recknor C, Nordsletten L, Moore KA, Lavecchia C, Zhang J, Mesenbrink P, Hodgson PK, Abrams K, Orloff JJ, Horowitz Z, Eriksen EF, Boonen S, HORIZON Recurrent Fracture Trial (2007) Zoledronic acid in reducing clinical fracture and mortality after hip fracture. N Engl J Med 357:1799–1809

    Article  CAS  PubMed  Google Scholar 

  104. Eriksen EF, Lyles KW, Colon-Emeric CS, Pieper CF, Magaziner JS, Adachi JD, Hylstrup L, Recknor C, Nordsletten L, Lavecchia C, Hu H, Boonen S, Mesenbrink P (2009) Anti-fracture efficacy and reduction of mortality in relation to timing of the first dose of zoledronic acid after hip fracture. J Bone Miner Res 24:1308–1313

    Article  CAS  PubMed  Google Scholar 

  105. Reginster JY, Seeman E, De Vernejoul MC, Adami S, Compston J, Phenekos C, Devogelaer JP, Diaz-Curiel M, Sawacki A, Goemaere S, Sorensen OH, Felsenberg D, Meunier PJ (2005) Strontium ranelate reduces the risk of non-vertebral fractures in postmenopausal women with osteoporosis: treatment of peripheral osteoporosis (TROPOS) Study. J Clin Endocrinol Metab 90:2816–2822

    Article  CAS  PubMed  Google Scholar 

  106. Cummings SR, Martin JS, McClung MR, Siris ES, Eastell R, Reid IR, Delmas PD, Zoog HB, Austin M, Wang A, Kutilek S, Adami S, Zanchetta J, Libanati C, Siddhanti S, Christiansen C, FREEDOM Trial (2009) Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med 361:756–765

    Article  CAS  PubMed  Google Scholar 

  107. Jaglal SB, Weller I, Mamdani M, Hawker G, Kreder H, Jaakkimainen L, Adachi JD (2005) Population trends in BMD testing, treatment, and hip and wrist fracture rates: are the hip fracture projections wrong? J Bone Miner Res 20:898–905

    Article  PubMed  Google Scholar 

  108. Berry SD, Samelson EJ, Ngo L, Bordes M, Broe KE, Kiel DP (2008) Subsequent fracture in nursing home residents with a hip fracture: a competing risks approach. J Am Geriatr Soc 56:1887–1892

    Google Scholar 

  109. Magaziner J, Hawkes W, Hebel JR, Zimmerman SI, Fox KM, Dolan M, Felsenthal G, Kenzora J (2000) Recovery from hip fracture in eight areas of function. J Gerontol A Biol Sci Med Sci 55:487–498

    Google Scholar 

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Pfeifer, M., Minne, H.W. Musculoskeletal rehabilitation after hip fracture: a review. Arch Osteoporos 5, 49–59 (2010). https://doi.org/10.1007/s11657-010-0050-8

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