Skip to main content

Advertisement

SpringerLink
Log in

Validation and cross-cultural adaptation of the disease-specific questionnaire MSQOL-54 in Serbian multiple sclerosis patients sample

  • Brief Communication
  • Published:
Quality of Life Research Aims and scope Submit manuscript

Abstract

The objective of this study was to translate the MSQOL-54 into Serbian, and investigate the validity of the translated and cross-culturally adapted inventory in Serbian MS patients. The questionnaire was validated in 200 consecutive MS patients seen between February and September 2005 at the Institute of Neurology, Clinical center of Serbia, in Belgrade. The translation followed an internationally accepted methodology. Associations between age, gender, education, marital and employment status, disease course, the expanded disability status scale (EDSS) score, and the MSQOL-54 physical and mental health composite scores were determined. Patients’ participation in the assessment was satisfactory and all scales fulfilled the usual psychometric standards. Highly significant inverse relationship was found between both composite scores and clinical characteristics of the disease, the EDSS and the disease course. Additionally, both composite scores, correlated significantly with patients’ age, education and employment status. The Serbian-translated version of this questionnaire may be useful as clinical outcome measures in patients with MS.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Vickrey, B. G., Hays, R. D., Harooni, R, Myers, L. W., & Ellison, G. W. (1995). A health-related quality of life measure for multiple sclerosis. Quality of Life Research, 4, 187–206.

    Article  PubMed  CAS  Google Scholar 

  2. Acquadro, C., Lafortune, L., & Mear, I. (2003). Quality of life in multiple sclerosis: Translation in French Canadian of the MSQoL-54. Health Quality of Life Outcomes, 1, 70–76.

    Article  Google Scholar 

  3. Solari, A., Filippini, G., Mendozzi, L., Ghezzi, A., Cifani, S., Barbieri, E., Baldini, S., Salmaggi, A., Mantia, L. L., Farinotti, M., Caputo, D., & Mosconi, P. (1999). Validation of Italian multiple sclerosis quality of life 54 questionnaire. Journal Neurology, Neurosurgery and Psychiatry, 67, 158–162.

    Article  CAS  Google Scholar 

  4. Vernay, D., Gerbaud, L., Biolay, S., Coste, J., Debourse, J., Aufauvre, D., Beeton, C., Colamarino, N., Glandier, P. Y., Dordain, G., & Clavelou, P. (2000). Quality of life and multiple sclerosis: Validation of the French version of the self-questionnaire (SEP-59). Revue Neurologique, 156, 247–263.

    PubMed  CAS  Google Scholar 

  5. Yamamoto, T., Ogata, K., Katagishi, M., Shimizu, H., Ogawa, M., Yamamura, T., & Kawai M. (2004). Validation of the Japanese-translated version Multiple Sclerosis Quality of Life-54 instrument. Rinsho Shinkeigoku, 44, 417–421.

    Google Scholar 

  6. Miller, A., & Dishon, S. (2005). Health-related quality of life in multiple sclerosis: Psychometric analysis of inventories. Multiple Sclerosis, 11, 450–458.

    Article  PubMed  Google Scholar 

  7. Idiman, E., Uzunel, F., Ozakbas, S., Yozbatiran, N., Oguz, M., Calioglu, B., Gokce, N., & Bahar, Z. (2006). Cross-cultural adaptation and validation of multiple sclerosis quality of life questionnaire (MSQOL-54) in a Turkish multiple sclerosis sample. Journal of Neurological Sciences, 240, 77–80.

    Article  Google Scholar 

  8. Aymerich, M., Gullamon, I., Perkal, H., Nos, C., Porcel, J., Berra, S., Rajmil, L., & Montalban, X. (2006). Spanish adaptation of the disease-specific questionnaire MSQOL-54 in multiple sclerosis patients. Neurologia, 21, 181–187.

    Article  PubMed  CAS  Google Scholar 

  9. McDonald, W. I., Compston, A., Edan, G., et al. (2001). Recommended diagnostic criteria for multiple sclerosis: guidelines from the International panel on the diagnosis of multiple sclerosis. Annals of Neurology, 50, 121–127.

    Article  PubMed  CAS  Google Scholar 

  10. Ware, J. E., Snow, K. K., Kosinski, M., et al. (1993). SF-36 health survey manual and interpretation guide. Boston: Nimrod Press.

    Google Scholar 

  11. Mear, I. (2002). Difficulties of international clinical trials: Cultural adaptation of quality of life questionnaires. In O. Chassany & C. Caulin (Eds.) Health-related quality of life and patient-reported outcomes: Scientific and useful outcome criteria (pp. 55–62). Paris: Springer Verlag Publishers.

    Google Scholar 

  12. SF-36 Health Survey (Original version) Language Recalls. Retrieved January 10, 2007 from http://www.qualitymetric.com

  13. Kurtzke, J. F. (1983). Rating neurologic instrument in multiple sclerosis: An expanded disability status scale (EDSS). Neurology, 33, 1444–1452.

    PubMed  CAS  Google Scholar 

  14. Bland, J. M., & Altman, D. G. (1997). Cronbach’s alpha. British Medical Journal, 317, 572.

    Google Scholar 

  15. Freeman, J. A., Hobart, J. C., & Thompson, A. J. (2001). Does adding MS-specific items to a generic measure (the SF-36) improve measurement? Neurology, 57, 68–74.

    PubMed  CAS  Google Scholar 

Download references

Acknowledgements

We sincerely appreciate Dr Barbara Vickrey for allowing us to adapt the original version of the MSQoL-54. This work was supported by Ministry of Science and Environmental Protection of Republic of Serbia (grant No 145045).

Author information

Authors and Affiliations

  1. Institute of Epidemiology, School of Medicine, University of Belgrade, Visegradska 26A, Belgrade, 11000, Serbia and Montenegro

    Tatjana Pekmezovic & Darija Kisic Tepavcevic

  2. Institute of Neurology, Clinical Center of Serbia, Belgrade, Serbia and Montenegro

    Tatjana Pekmezovic, Jelena Kostic & Jelena Drulovic

Authors
  1. Tatjana Pekmezovic
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Darija Kisic Tepavcevic
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Jelena Kostic
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Jelena Drulovic
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Tatjana Pekmezovic.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pekmezovic, T., Kisic Tepavcevic, D., Kostic, J. et al. Validation and cross-cultural adaptation of the disease-specific questionnaire MSQOL-54 in Serbian multiple sclerosis patients sample. Qual Life Res 16, 1383–1387 (2007). https://doi.org/10.1007/s11136-007-9234-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11136-007-9234-0

Keywords

Search

Navigation