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Congestive Heart Failure and Myocarditis After Seroconverison for Toxoplasmosis in Two Immunocompetent Patients

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Abstract

 Two cases of myocarditis and congestive heart failure in immunocompetent patients with seroconversion for toxoplasmosis are reported. Serological tests showed that in the first case the cardiac manifestations occurred at the time of seroconversion (low IgG, raised IgM and IgA), whereas in the second case they occurred several months after the initial infection when IgM was decreasing, IgG levels were very high (>1000 IU/ml) and IgG had high affinity for the antigen. The pathophysiological mechanisms underlying cardiac involvement in acute or chronic toxoplasmosis are discussed.

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Authors and Affiliations

  1. Service de Parasitologie-Mycologie, CHU d'Amiens, Hôpital Sud, 80000 Amiens, France e-mail: jac-bri.chandenier@wanadoo.fr, , , , , , FR

    J. Chandenier & C. Raccurt

  2. Service de Réanimation Cardiologique, CHU d'Amiens, Hôpital Sud, 80000 Amiens, France, , , , , , FR

    G. Jarry

  3. Service de Pédiatrie I, CHU d'Amiens, Hôpital Nord, 80000 Amiens, France, , , , , , FR

    D. Nassif & E. Bourges-Petit

  4. Service de Pathologies Infectieuses CHU d'Amiens, Hôpital Nord, 80000 Amiens, France, , , , , , FR

    Y. Douadi

  5. Service de Parasitologie-Mycologie, Hôpital de la Salpétrière, 75013 Paris, France, , , , , , FR

    L. Paris

  6. Institut de Puériculture de Paris, Laboratoire de la Toxoplasmose, 75014 Paris, France, , , , , , FR

    P. Thulliez

Authors
  1. J. Chandenier
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  2. G. Jarry
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  3. D. Nassif
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  4. Y. Douadi
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  5. L. Paris
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  6. P. Thulliez
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  7. E. Bourges-Petit
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  8. C. Raccurt
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Chandenier, J., Jarry, G., Nassif, D. et al. Congestive Heart Failure and Myocarditis After Seroconverison for Toxoplasmosis in Two Immunocompetent Patients. EJCMID 19, 375–379 (2000). https://doi.org/10.1007/s100960050498

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  • DOI: https://doi.org/10.1007/s100960050498

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