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Aseptisches Operieren in Orthopädie und Unfallchirurgie

Tatsächlicher Stand

Aseptic operations in orthopedics and trauma surgery

Current state of the art

  • Leitthema
  • Published:
Trauma und Berufskrankheit

Zusammenfassung

Hintergrund

Postoperative Wundinfektionen in Unfallchirurgie und Orthopädie sind in einer Ära von technischem Fortschritt und alternder Bevölkerung von besonderer Bedeutung, da sie meist einen komplizierten, langwierigen und teuren Heilungsverlauf verursachen.

Erregerspektrum

Typische Erreger sind Staphylococcus aureus, Biofilm produzierender Staphylococcus epidermidis, hämolysierende Streptokokken und die gramnegativen Stäbchen Escherichia coli und Pseudomonas aeruginosa.

Problematik

Kritische Punkte in der Infektiogenese sind präoperative Hautdesinfektion, Händehygiene, sichere chirurgische Technik, Barrieremaßnahmen zum Schutz vor Erregerverbreitung sowie ein funktionierendes Hygieneregime im Rahmen eines adäquaten Qualitätsmanagements. Die Basisinfektrate in Unfallchirurgie und Orthopädie ist im Vergleich zu anderen chirurgischen Disziplinen höher, nichtsdestotrotz kann durch Implementierung risikoadaptierter Präventionsmaßnahmen eine Verbesserung erzielt werden.

Abstract

Background

Surgical site infections (SSI) in traumatology and orthopedics in the era of increasing technical improvements and an aging and increasingly fragile population are of crucial importance mostly showing complicated, long-term and expensive outcome.

Spectrum of pathogens

Typical wound pathogens of these infections include Staphylococcus aureus, biofilm-producing Staphylococcus epidermidis, hemolytic Streptococci and the Gram-negative rods Escherichia coli and Pseudomonas aeruginosa.

Problems

Critical points in the development of SSI are preoperative skin antisepsis, hand hygiene, safe and skilled technique by surgeons, barrier nursing to prevent spread of pathogens, postoperative wound surveillance and a functioning hygiene regime in the context of an adequate quality management system. Baseline infection incidence in traumatology and orthopedics is inherently higher compared with other surgical disciplines; nevertheless, significant improvements can be achieved by the implementation of risk-adapted infection control measures.

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Literatur

  1. Altemeier WA, Culbertson WR, Hummel RP (1968) Surgical considerations of endogenous infections – sources, types and methods of control. Surg Clin North Am 48(1):227–240

    PubMed  CAS  Google Scholar 

  2. AORN Recommended Practices Committee (2006) Recommended practices for maintaining a sterile field. AORN J 83:402–404, 407–410, 413–416

    Article  Google Scholar 

  3. Beldame J, Lagrave B, Lievain L et al (2012) Surgical glove bacterial contamination and perforation during total hip arthroplasty implantation: when gloves should be changed. Orthop Traumatol Surg Res 98:432–440

    Article  PubMed  CAS  Google Scholar 

  4. Bernau A, Heeg P (1985) Experimentelle Untersuchungen zu Fragen der Hautdesinfektion. Orthop Prax 21:351–358

    Google Scholar 

  5. Berthelot P, Grattard F, Cazorla C et al (2010) Is nasal carriage of Staphylococcus aureus the main acquisition pathway for surgical-site infection in orthopaedic surgery? Eur J Clin Microbiol Infect Dis 29:373–382

    Article  PubMed  CAS  Google Scholar 

  6. Bible J, Biswas D, Whang P et al (2009) Which regions of the operating gown should be considered most sterile? Clin Orthop Relat Res 467:825–830

    Article  PubMed  Google Scholar 

  7. Boekel P, Blackshaw R, Bavel D van, Hau R (2012) Sterile stockinette in orthopaedic surgery: a possible pathway for infection. ANZ J Surg 82:838–843

    Article  PubMed  Google Scholar 

  8. Daeschlein G, Napp M, Bluhm J et al (eingereicht) Effect of pre-operative skin sealing with cyanoacrylate on microbial contamination of surgical wounds following trauma surgery: a prospective, blinded, controlled, randomized clinical trial. eingereicht

  9. Daeschlein G, Napp M, Podewils S von et al (eingereicht) In vitro susceptibility of multidrug resistant skin and wound pathogens against low temperature atmospheric pressure plasma jet (APPJ) and dielectric barrier discharge plasma (DBD). eingereicht

  10. Darouiche RO (2001) Device-associated infections: a macroproblem that starts with microadherence. Clin Infect Dis 33(9):1567–1572

    Article  PubMed  CAS  Google Scholar 

  11. Davis N, Curry A, Gambhir AK et al (1999) Intraoperative bacterial contamination in operations for joint replacement. J Bone Joint Surg Br 81:886–889

    Article  PubMed  CAS  Google Scholar 

  12. Dohmen PM, Konertz W (2007) A review of current strategies to reduce intraoperative bacterial contamination of surgical wounds. GMS Krankenhaushyg Interdiszip 2(2):Doc38

    Google Scholar 

  13. Donlan RM (2002) Biofilms: microbial life on surfaces. Emerg Infect Dis 8(9):881–890

    Article  PubMed  Google Scholar 

  14. Eckersley JR, Williamson DM (1990) Glove punctures in an orthopaedic trauma unit. Injury 21:177–178

    Article  PubMed  CAS  Google Scholar 

  15. Eiff C von, Becker K, Machka K et al (2001) Nasal carriage as a source of Staphylococcus aureus bacteremia. Study Group. N Engl J Med 344:11–16

    Article  Google Scholar 

  16. Evans RP (2009) Surgical site infection prevention and control: an emerging paradigm. J Bone Joint Surg Am [Suppl 6] 91:2–9

    Google Scholar 

  17. Garvin KL, Konigsberg BS (2011) Infection following total knee arthroplasty: prevention and management. J Bone Joint Surg Am 93:1167–1175

    PubMed  Google Scholar 

  18. Givissis P, Karataglis D, Antonarakos P et al (2008) Suction during orthopaedic surgery. Howe safe is the suction tip? Acta Orthop Belg 74(4):531–533

    PubMed  Google Scholar 

  19. Graf K, Ott E, Vonberg R et al (2011) Surgical site infections – economic consequences for the health care system. Langenbecks Arch Surg 396:453–459

    Article  PubMed  Google Scholar 

  20. Haas JP, Evans AM, Preston KE, Larson EL (2005) Risk factors for surgical site infection after cardiac surgery: the role of endogenous flora. Heart Lung 34(2):108–114

    Article  PubMed  Google Scholar 

  21. Hansis M, Jakschik J (2001) Chirurgie und Orthopädie. In: Kramer A, Heeg P, Botzenhart K (Hrsg) Krankenhaus- und Praxishygiene. Urban & Fischer, München, S 456–462

  22. Harnoss JC, Partecke LI, Heidecke CD et al (2009) Concentration of bacteria passing through puncture holes in surgical gloves. Am J Infect Control 38:154–158

    Article  PubMed  Google Scholar 

  23. Houang ET, Ahmet Z (1991) Intraoperative wound contamination during abdominal hysterectomy. J Hosp Infect 19:181–189

    Article  PubMed  CAS  Google Scholar 

  24. Hübner NO, Assadian O, Grohmann SA et al (2011) Efficacy of five alcohol-based skin antiseptics on sebaceous skin used at shorter application times than the current recommendation of 10 minutes. Eur J Clin Microbiol Infect Dis 30(7):825–829

    Article  PubMed  Google Scholar 

  25. James RC, Macleod CJ (1961) Induction of staphylococcal infections in mice with small inocula introduced on sutures. Br J Exp Pathol 42:266–277

    PubMed  CAS  Google Scholar 

  26. Kalmeijer MD, Nieuwland-Bollen E van, Bogaers-Hofman D, Baere GA de (2000) Nasal carriage of Staphylococcus aureus is a major risk factor for surgical-site infections in orthopedic surgery. Infect Control Hosp Epidemiol 21:319–323

    Article  PubMed  CAS  Google Scholar 

  27. Kalmeijer MD, Coertjens H, Nieuwland-Bollen PM van et al (2002) Surgical site infections in orthopedic surgery: the effect of mupirocin nasal ointment in a double-blind, randomized, placebo-controlled study. Clin Infect Dis 35:353–358

    Article  PubMed  CAS  Google Scholar 

  28. Kommission für Krankenhaushygiene und Infektionsprävention beim Robert Koch-Institut (RKI) (2007) Prävention postoperativer Infektionen im Operationsgebiet. Empfehlung der Kommission für Krankenhaushygiene und Infektionsprävention beim Robert Koch-Institut. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 50:377–393

    Article  Google Scholar 

  29. Kramer A, Assadian O, Lademann J (2010) Prevention of postoperative wound infections by covering the surgical field with iodine-impregnated incision drape (Ioban® 2). GMS Krankenhaushyg Interdiszip 5(2):Doc08(20100921)

    Google Scholar 

  30. Krikorian R, Lozach-Perlant A, Ferrier-Rembert A et al (2007) Standardization of needlestick injury and evaluation of novel virus-inhibiting protective glove. J Hosp Infect 66:339–345

    Article  PubMed  CAS  Google Scholar 

  31. Lademann O, Kramer A, Richter H et al (2011) Skin disinfection by plasma-tissue interaction: comparison of the effectivity of tissue-tolerable plasma and a standard antiseptic. Skin Pharmacol Physiol 24(5):284–288

    Article  PubMed  CAS  Google Scholar 

  32. Lademann O, Richter H, Meinke MC et al (2011) Drug delivery through the skin barrier enhanced by treatment with tissue-tolerable plasma. Exp Dermatol 20(6):488–490

    Article  PubMed  Google Scholar 

  33. Lademann J, Richter H, Schanzer S et al (2012) Comparison of the antiseptic efficacy of tissue-tolerable plasma and an octenidine hydrochloride-based wound antiseptic on human skin. Skin Pharmacol Physiol 25(2):100–106

    Article  PubMed  CAS  Google Scholar 

  34. Laine T, Aarnio P (2004) Glove perforation in orthopaedic and trauma surgery. A comparison between single, double indicator gloving and double gloving with two regular gloves. J Bone Joint Surg Br 86:898–900

    Article  PubMed  CAS  Google Scholar 

  35. Lew DP, Pittet D, Waldvogel FA W (2004) Infections that complicate the insertion of prosthetic devices. Lippincott Williams & Wilkins, Philadelphia

  36. Lipp A, Phillips C, Harris P, Dowie I (2011) Cyanoacrylate as a microbial sealant: examining the evidence. Clin Feature 21(3):88–92

    Google Scholar 

  37. Maffulli N, Capasso G, Testa V (1991) Glove perforation in pediatric orthopaedic surgery. J Pediatr Orthop 11:25–27

    Article  PubMed  CAS  Google Scholar 

  38. Mangram AJ, Horan TC, Pearson ML et al (1999) Guidelines for prevention of surgical site infection, 1999. Hospital Infection Control Practices Advisory Committee. Infect Control Hosp Epidemiol 20:250–278

    Article  PubMed  CAS  Google Scholar 

  39. Nade S (1990) Infection after joint replacement – what would Lister think? Med J Aust 152:394–397

    PubMed  CAS  Google Scholar 

  40. Newman JB, Bullock M, Goyal R (2007) Comparison of glove donning techniques for the likelihood of gown contamination. An infection control study. Acta Orthop Belg 73(6):765–771

    PubMed  Google Scholar 

  41. NRZ (Nationales Referenzzentrum für Surveillance von nosokomialen Infektionen) (2013) KISS (Krankenhaus-Infektions-Surveillance-System), Modul OP-KISS, Referenzdaten, Berechnungszeitraum: Januar 2008 bis Dezember 2012 – Erregerstatistik der häufigsten Erreger. NRZ, Berlin. http://www.nrz-hygiene.de. Zugegriffen: 06.08.2013

  42. Peters PG, Laughlin RT, Markert RJ et al (2012) Timing of C-arm drape contamination. Surg Infect (Larchmt) 13(2):110–113

    Google Scholar 

  43. Poultsides LA, Liaropoulos LL, Malizos KN (2010) The socioeconomic impact of musculoskeletal infections. J Bone Joint Surg Am 92:e13

    Article  PubMed  Google Scholar 

  44. Rüden H, Daschner F, Schumacher M (1995) Nosokomiale Infektionen in Deutschland – Erfassung und Prävention (NIDEP-Studie), Bd 56. Bundesministerium für Gesundheit, Berlin

  45. Statistisches Bundesamt (2013) Operationen und Prozeduren der vollstationären Patientinnen und Patienten in Krankenhäusern. Gliederungsmerkmale: Jahre, Behandlungsort, Alter, Geschlecht. Statistisches Bundesamt, Zweigstelle Bonn. http://www.gbe-bund.de/gbe10/i?i=662D. Zugegriffen: 06.08.2013

  46. Stewart PS, Costerton JW (2001) Antibiotic resistance of bacteria in biofilms. Lancet 358(9276):135–138

    Article  PubMed  CAS  Google Scholar 

  47. Tanner J (2012) Methods of skin antisepsis for preventing SSIs. Nurs Times 108(37):20–22

    PubMed  Google Scholar 

  48. Thanni LO, Yinusa W (2003) Incidence of glove failure during orthopedic operations and the protective effect of double gloves. J Natl Med Assoc 95:1184–1188

    PubMed  Google Scholar 

  49. Thiele RH, Huffmyer JL, Nemergut EC (2008) The ‚six sigma approach‘ to the operating room environment and infection. Best Pract Res Clin Anaesthesiol 22:537–552

    Article  PubMed  Google Scholar 

  50. Trampuz A, Zimmerli W (2006) Diagnosis and treatment of infections associated with fracture-fixation devices. Injury 37:S59–S66

    Article  PubMed  Google Scholar 

  51. Trampuz A, Osmon DR, Hanssen AD et al (2003) Molecular and antibiofilm approaches to prosthetic joint infection. Clin Orthop Relat Res 414:69–88

    Article  PubMed  Google Scholar 

  52. Tunnevall TG (1991) Postoperative wound infections and surgical face masks: a controlled study. World J Surg 15:383–388

    Article  Google Scholar 

  53. Valentine RJ, Weigelt JA, Dryer D, Rodgers C (1986) Effect of remote infections on clean wound infection rates. Am J Infect Control 14:64–67

    Article  PubMed  CAS  Google Scholar 

  54. Webster J, Alghamdi AA (2007) Use of plastic adhesive drapes during surgery for preventing surgical site infection. Cochrane Database Syst Rev 4:CD006353

    PubMed  Google Scholar 

  55. Wiley AM, Ha’eri GB (1979) Routes of infection. A study of using „tracer particles“ in the orthopedic operating room. Clin Orthop Relat Res 139:150–155

    PubMed  Google Scholar 

  56. Yinusa W, Li YH, Chow W et al (2004) Glove punctures in orthopaedic surgery. Int Orthop 28:36–39

    Article  PubMed  CAS  Google Scholar 

  57. Zimmerli W, Waldvogel FA, Vaudaux P et al (1982) Pathogenesis of foreign body infection: description and characteristics of an animal model. J Infect Dis 146(4):487–497

    Article  PubMed  CAS  Google Scholar 

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Einhaltung ethischer Richtlinien

Interessenkonflikt. M. Napp, G. Daeschlein, D. Gümbel, J. Lange, P. Hinz, A. Ekkernkamp geben an, dass kein Interessenkonflikt besteht. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.

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Napp, M., Daeschlein, G., Gümbel, D. et al. Aseptisches Operieren in Orthopädie und Unfallchirurgie. Trauma Berufskrankh 15, 177–183 (2013). https://doi.org/10.1007/s10039-013-2008-8

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  • DOI: https://doi.org/10.1007/s10039-013-2008-8

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