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Adenoid cystic carcinoma of the skull base mimicking temporomandibular disorder

  • Case Report
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Abstract

Background

Temporomandibular disorder (TMD) involves problems of the temporomandibular joint and its adjacent muscular system. Because TMD prevalence is high among Western populations, complaints in these regions are generally attributed to TMD. However, in rare cases, TMD symptoms are mimicked by malignant tumors of the head.

Case report

Upon first presentation, an 18-year-old female complained about typical symptoms of TMD. After an initial splint therapy and physiotherapy, painful symptoms increased significantly. Twelve weeks after initial diagnosis, further diagnostic imaging revealed a tumor formation at the skull base with infiltration of the infratemporal fossa. Histological evaluation confirmed the diagnosis of adenoid cystic carcinoma. Two years after resection of the tumor, lung metastases were detected with no option of curative treatment.

Conclusion

TMD symptoms, which are refractory to treatment or exhibit significant worsening during therapy, should be regarded as warning signals and as an indication that early further diagnostic imaging is warranted.

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References

  1. Mock D (1999) The differential diagnosis of temporomandibular disorders. J Orofac Pain 13:246–250

    CAS  PubMed  Google Scholar 

  2. Stowell AW, Gatchel RJ, Wildenstein L (2007) Cost-effectiveness of treatments for temporomandibular disorders: biopsychosocial intervention versus treatment as usual. J Am Dent Assoc 138:202–208

    Article  PubMed  Google Scholar 

  3. Heo MS, An BM, Lee SS, Choi SC (2003) Use of advanced imaging modalities for the differential diagnosis of pathoses mimicking temporomandibular disorders. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 96:630–638

    Article  PubMed  Google Scholar 

  4. Kruse ALD, Luebbers HT, Obwegeser JA, Edelmann L, Graetz KW (2010) Temporomandibular disorders associated with metastases to the temporomandibular joint: a review of the literature and three additional cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 110:e21–e28

    Article  PubMed  Google Scholar 

  5. Herrera AF, Mercuri LG, Petruzzelli G, Rajan P (2007) Simultaneous occurrence of two different low-grade malignancies mimicking temporomandibular joint dysfunction. J Oral Maxillofac Surg 65:1353–1358

    Article  PubMed  Google Scholar 

  6. Cohen SG, Quinn PD (1988) Facial trismus and myofascial pain associated with infections and malignant disease. Report of five cases. Oral Surg Oral Med Oral Pathol 65:538–544

    Article  CAS  PubMed  Google Scholar 

  7. Herrera AF, Mercuri LG, Picken MM (2002) Reactive granulomatous lesion in the pterygomandibular fossa mimicking a temporomandibular disorder. J Oral Maxillofac Surg 60:1203–1206

    Article  PubMed  Google Scholar 

  8. Lee JS, Iranmanesh A, Schmidt BL, Fischbein NJ, McKenna SJ (2005) Limited oral opening in a 43-year-old man. J Oral Maxillofac Surg 63:103–110

    Article  PubMed  Google Scholar 

  9. Ellington CL, Goodman M, Kono SA, Grist W, Wadsworth T, Chen AY, Owonikoko T, Ramalingam S, Shin DM, Khuri FR, Beitler JJ, Saba NF (2012) Adenoid cystic carcinoma of the head and neck. Incidence and survival trends based on 1973–2007 surveillance, epidemiology, and end results data. Cancer 118:4444–4451

    Article  PubMed  Google Scholar 

  10. Khan J, Quek SY, Markman S (2010) Nasopharyngeal carcinoma masquerading as TMJ orofacial pain. Quintessence Int 41:387–389

    PubMed  Google Scholar 

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The authors declare that there are no conflicts of interest

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Correspondence to Jan Rustemeyer.

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Sari-Rieger, A., Hassfeld, S., Junker, K. et al. Adenoid cystic carcinoma of the skull base mimicking temporomandibular disorder. Oral Maxillofac Surg 18, 115–118 (2014). https://doi.org/10.1007/s10006-013-0414-5

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  • DOI: https://doi.org/10.1007/s10006-013-0414-5

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