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Xanthogranulomatous sialadenitis clinically mimicking a malignancy: case report and review of the literature

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Abstract

Background

Xanthogranulomatous tissue reaction is a well-documented process that is most common in kidney. There are other uncommon sites being documented as case reports in the literature. We would like to describe the clinicopathologic findings in a case of xanthogranulomatous sialadenitis that involved the parotid gland, which was clinically thought to be a tumoral mass, and compare it with the 4 previously reported cases.

Case report

A 52-year-old man presented with a left parotid mass. Fine needle aspiration biopsy was consistent with Warthin's tumor. The mass lesion was excised.

Discussion

The lesion measured 2.5 × 1.5 × 1.5 cm. Microscopic examination revealed sheets of foamy macrophages centrally admixed with neutrophils, eosinophils, lymphocytes, plasma cells and scattered giant cells indicating a xanthogranulomatous reaction.

As a conclusion xanthogranulomatous tissue reaction can mimic neoplasms.

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Conflicts of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Pathology, İstanbul Bilim University, Faculty of Medicine, Istanbul, Turkey

    İlknur Türkmen, Nuray Başsüllü & Gülen Bülbül Doğusoy

  2. Department of ENT, İstanbul University, İstanbul Medical Faculty, Istanbul, Turkey

    İsmet Aslan

  3. Department of Pathology, Near East University, Faculty of Medicine, Nicosia, Cyprus

    Cem Çomunoğlu

  4. Acıbadem Cad. Hukukçular ve İdareciler Sitesi, I Blok 142-I/23 Kadıköy, Istanbul, Turkey

    İlknur Türkmen

Authors
  1. İlknur Türkmen
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  2. Nuray Başsüllü
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  3. İsmet Aslan
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  4. Cem Çomunoğlu
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  5. Gülen Bülbül Doğusoy
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Correspondence to İlknur Türkmen.

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Türkmen, İ., Başsüllü, N., Aslan, İ. et al. Xanthogranulomatous sialadenitis clinically mimicking a malignancy: case report and review of the literature. Oral Maxillofac Surg 16, 389–392 (2012). https://doi.org/10.1007/s10006-011-0307-4

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  • DOI: https://doi.org/10.1007/s10006-011-0307-4

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