Abstract
Purpose
Preoperative assessments regarding a patient’s immunological and nutritional condition are required to predict the outcomes of patients with malignant tumors. The aim of the current study was to clarify the significance of Onodera’s prognostic nutritional index (OPNI), which can simply account for the immunological and nutritional conditions, in patients with colorectal carcinoma.
Methods
The correlations of the preoperative OPNI value with clinicopathological features were examined in 219 patients with colorectal carcinoma who had been surgically treated.
Results
Not only the tumor stage (P = 0.028) and venous invasion (P = 0.002), but also an OPNI of less than 40 (P = 0.002) were found to be independently correlated with a worse prognosis of patients with colorectal carcinoma.
Conclusion
The preoperative OPNI can be used as a simple prognostic indicator in colorectal carcinoma.
Similar content being viewed by others
References
Delmore G. Assessment of nutritional status in cancer patients: widely neglected? Support Care Cancer. 1997;5:376–80.
Onodera T, Goseki N, Kosaki G. Prognostic nutritional index in gastrointestinal surgery of malnourished cancer patients. Nippon Geka Gakkai Zasshi. 1984;85:1001–5 (in Japanese with an English abstract).
Nozoe T, Kimura Y, Ishida M, Saeki H, Korenaga D, Sugimachi K. Correlation of pre-operative nutritional condition with post-operative complications in surgical treatment for oesophageal carcinoma. Eur J Surg Oncol. 2002;28:396–400.
Nozoe T, Ninomiya M, Maeda T, Matsukuma A, Nakashima H, Ezaki T. Prognostic nutritional index: a tool to predict the biological aggressiveness of gastric carcinoma. Surg Today. 2010;40:440–3.
Japanese Society for Cancer of the Colon and Rectum. Japanese classification: colorectal carcinoma, 2nd ed. Tokyo: Kanehara; 1997.
Sobin L, Gospodarowicz M, Wittekind C; International Union Against Cancer. TNM classification of malignant tumours, 7th ed. New York: Wiley-Blackwell; 2009. p. 73–7.
Boonpipattanapong T, Chewatanakornkul S. Preoperative carcinoembryonic antigen and albumin in predicting survival in patients with colon and rectal carcinomas. J Clin Gastroenterol. 2006;40:592–5.
Walsh SR, Cook EJ, Goulder F, Justin TA, Keeling NJ. Neutrophil–lymphocyte ratio as a prognostic factor in colorectal cancer. J Surg Oncol. 2005;91:181–4.
Nozoe T, Yasuda M, Honda M, Inutsuka S, Korenaga D. Obstructing carcinomas of the colon and rectum have a smaller size compared with those of non-obstructing carcinomas. Oncol Rep. 2001;8:1313–5.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Nozoe, T., Kohno, M., Iguchi, T. et al. The prognostic nutritional index can be a prognostic indicator in colorectal carcinoma. Surg Today 42, 532–535 (2012). https://doi.org/10.1007/s00595-011-0061-0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00595-011-0061-0