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Major mesh-related complications following hernia repair

Events reported to the Food and Drug Administration

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Abstract

Mesh material affects complications following hernia repair. Medical device reports on the use of surgical mesh for hernia repair were reviewed from the Food and Drug Administration’s (FDA) Manufacturer User Facility Device Experience Database from January 1996 to September 2004. We analyzed 252 adverse event reports related to the use of surgical mesh for hernia repair. Adverse events included infection (42%, 107 reports), mechanical failure (18%, 46), pain (9%, 23), reaction (8%, 20), intestinal complications (7%, 18), adhesions (6%, 14), seroma (4%, 9), erosion (2%, 6), and other (4%, 9). Compared to all other mesh types, Sepra/polypropylene mesh had more mechanical failures (80 vs 14%, p < 0.05), biomaterial mesh had more reactions (57 vs 7%, p < 0.05), polytetrafluoroethylene (PTFE)/polypropylene mesh had more intestinal complications (14 vs 7%, p < 0.05), and PTFE mesh tended to have more infections (75 vs 41% all other, p = 0.07). Death occurred in 2% (5). We conclude that specific mesh materials are related to specific complications.

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References

  1. Baptista ML, Bonsack ME,Delaney JP (2000) Seprafilm reduces adhesions to polypropylene mesh. Surgery 128:86–92

    Article  PubMed  CAS  Google Scholar 

  2. Burger JW, Luijendijk RW, Hop WC, Halm JA, Verdaasdonk EG, Jeekel J (2004) Long-term follow-up of a randomized controlled trial of suture versus mesh repair of incisional hernia. Ann Surg 240:578–585

    PubMed  Google Scholar 

  3. Diaz JJ Jr, Gray BW, Dobson JM, Grogan EL, May AK, Miller R, Guy J, O’Neill P, Morris JA Jr (2004) Repair of giant abdominal hernias: does the type of prosthesis matter? Am Surg 70:396–402

    PubMed  Google Scholar 

  4. Fitzgibbons RJ, Greenburg AG (eds) (2002) Nyhus and Condon’s hernia, 5th ed. Lippincott Williams & Wilkins, Philadelphia

    Google Scholar 

  5. Klinge U, Junge K, Spellerberg B, Piroth C, Klosterhalfen B, Schumpelick V (2002) Do multifilament alloplastic meshes increase the infection rate? Analysis of the polymeric surface, the bacteria adherence, and the in vivo consequences in a rat model. J Biomed Mater Res 63:765–771

    PubMed  CAS  Google Scholar 

  6. Klinge U, Klosterhalfen B, Muller M, Ottinger AP, Schumpelick V (1998) Shrinking of polypropylene mesh in vivo: an experimental study in dogs. Eur J Surg 164:965–969

    PubMed  CAS  Google Scholar 

  7. Leber GE, Garb JL, Alexander AI, Reed WP (1998) Long-term complications associated with prosthetic repair of incisional hernias. Arch Surg 133:378–382

    PubMed  CAS  Google Scholar 

  8. Luijendijk RW, Hop WC, van den Tol MP, et al. (2000) A comparison of suture repair with mesh repair for incisional hernia. N Engl J Med 343:392–398

    Article  PubMed  CAS  Google Scholar 

  9. Matthews BD, Mostafa G, Carbonell AM, Joels CS, Kercher KW, Austin C, Norton HJ, Heniford BT (2005) Evaluation of adhesion formation and host tissue response to intra-abdominal polytetrafluoroethylene mesh and composite prosthetic mesh(1). J Surg Res 123:227–234

    Article  PubMed  CAS  Google Scholar 

  10. Matthews BD, Pratt BL, Pollinger HS, Backus CL, Kercher KW, Sing RF, Heniford BT (2003) Assessment of adhesion formation to intra-abdominal polypropylene mesh and polytetrafluoroethylene mesh. J Surg Res 114:126–132

    Article  PubMed  CAS  Google Scholar 

  11. Menon NG, Rodriguez ED, Byrnes CK, Girotto JA, Goldberg NH, Silverman RP (2003) Revascularization of human acellular dermis in full-thickness abdominal wall reconstruction in the rabbit model. Ann Plastic Surg 50:523–527

    Google Scholar 

  12. Pans A, Elen P, Dewe W, Desaive C (1998) Long-term results of polyglactin mesh for the prevention of incisional hernias in obese patients. World J Surg 22:479–483

    Article  PubMed  CAS  Google Scholar 

  13. Riepe G, Loos J, Imig H, et al. (1997) Long-term in vivo alterations of polyester vascular grafts in humans. Eur J Vasc Endovasc Surg 13:540–548

    Article  PubMed  CAS  Google Scholar 

  14. Schmedt CG, Sauerland S, Bittner R (2005) Comparison of endoscopic procedures vs Lichtenstein and other open mesh techniques for inguinal hernia repair: a meta-analysis of randomized controlled trials. Surg Endosc 19: 188–199

    Article  PubMed  CAS  Google Scholar 

  15. Schumpelick V, Klinge U (2003) Prosthetic implants for hernia repair. Br J Surg 90:1457–1458

    Article  PubMed  CAS  Google Scholar 

  16. Simmermacher RK, Schakenraad JM, Bleichrodt RP (1994) Reherniation after repair of the abdominal wall with expanded polytetrafluoroethylene. J Am Coll Surg 178:613–616

    PubMed  CAS  Google Scholar 

  17. Usher FC, Allen JE Jr, Crosthwait RW, Cogan JE (1962) Polypropylene monofilament. A new, biologically inert suture for closing contaminated wounds. J Am Med Assoc 179:780–782

    CAS  Google Scholar 

  18. Wolstenholme JT (1956) Use of commercial Dacron fabric in the repair of inguinal hernias and abdominal wall defects. AMA Arch Surg 73:1004–1008

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Surgery, University of Colorado Health Sciences Center, Box C311, 4200 East Ninth Avenue, Denver, CO, 80262, USA

    T. N. Robinson, J. H. Clarke, J. Schoen & M. D. Walsh

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  1. T. N. Robinson
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  2. J. H. Clarke
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  3. J. Schoen
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  4. M. D. Walsh
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Correspondence to T. N. Robinson.

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Robinson, T.N., Clarke, J.H., Schoen, J. et al. Major mesh-related complications following hernia repair. Surg Endosc 19, 1556–1560 (2005). https://doi.org/10.1007/s00464-005-0120-y

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  • DOI: https://doi.org/10.1007/s00464-005-0120-y

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