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Evolution of lamellar macular hole studied by optical coherence tomography

  • Retinal Disorders
  • Published:
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Abstract

Purpose

To study the natural course of lamellar macular hole (LMH) as examined by optical coherence tomography (OCT) in a noncomparative observational case series.

Methods

Forty-one eyes of 41 patients with LMH were included in this analysis. Baseline and final OCT findings related to LMH diameter, foveal thickness and visual acuity (VA) were collected and compared. Mean follow-up was 37.1 months. Main outcome measures were best-corrected visual acuity (BCVA), diameter of the LMH opening, foveal thickness, epiretinal membrane (ERM), posterior vitreous detachment (PVD) and vitreoretinal traction.

Results

The diameter of the LMH increased by an average of 13.7%. A statistically significant association was found between the LMH diameter increase and the presence of ERM. The mean foveal thickness depicted a statistically significant decrease between the initial and the final examination. The decrease of the foveal thickness showed to correlate with visual acuity deterioration. BCVA was stable in 30 (78%) and deteriorated in 11 (22%) cases. In eight of the 11 cases, the visual acuity deterioration ranged from 2 to 15 letters.

Conclusion

We identified an increase of LMH diameter related to the presence of ERM and a decrease of the foveal thickness within a period of observation which ranged from 24 to 54 months (mean 37.1 months).

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Authors and Affiliations

  1. 2nd Department of Ophthalmology, University of Athens, 13, Likiou Street, 10674, Athens, Greece

    P. G. Theodossiadis, I. Vergados & M. Apostolopoulos

  2. 2nd Department of Ophthalmology, Henry Dunant Hospital, Athens, Greece

    V. G. Grigoropoulos, I. Emfietzoglou, P. Nikolaidis & G. P. Theodossiadis

Authors
  1. P. G. Theodossiadis
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  2. V. G. Grigoropoulos
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  3. I. Emfietzoglou
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  4. P. Nikolaidis
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  5. I. Vergados
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  6. M. Apostolopoulos
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  7. G. P. Theodossiadis
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Corresponding author

Correspondence to P. G. Theodossiadis.

Additional information

The study is not related with any proprietary or commercial interests. No sponsoring organizations have been involved and no grants were received from any organization or institution.

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Theodossiadis, P.G., Grigoropoulos, V.G., Emfietzoglou, I. et al. Evolution of lamellar macular hole studied by optical coherence tomography. Graefes Arch Clin Exp Ophthalmol 247, 13–20 (2009). https://doi.org/10.1007/s00417-008-0927-z

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  • DOI: https://doi.org/10.1007/s00417-008-0927-z

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