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Pulmonary and Mediastinal Bronchogenic Cysts: A Clinicopathologic Study of 33 Cases

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Abstract

Bronchogenic cysts are uncommon congenital anomalies of foregut origin and usually located within the mediastinum and the lung. A retrospective study of 33 thoracic bronchogenic cysts was undertaken to detail their clinicopathologic and radiologic features. There were 18 male and 15 female patients between 12 and 77 years of age with a mean age of 41 years. Thirty-one patients (94%) were symptomatic at the time of diagnosis and the chief complaint was chest pain (48.5%). Most of the cysts presented as homogeneous water-density shadows on standard chest radiographs. The location was intrapulmonary in 25 cases and mediastinal in 8 cases. Based on radiologic investigations, preoperative diagnosis of bronchogenic cyst was made in only 11 cases (33.34%). Surgical excision of the cyst was approached via thoracotomy in 32 cases and thoracoscopy in one case. Total excision of the cyst was performed in 31 cases and subtotal resection in 2 cases. Pathologic findings were consistent with bronchogenic cyst in all cases. During the follow-up period, which ranged between 1 month and 51 months, all patients were symptom-free with no evidence of recurrence. Complete surgical resection is recommended for all bronchogenic cysts to establish diagnosis, alleviate symptoms, and prevent complications.

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Abbreviations

BC:

bronchogenic cyst

MBC:

mediastinal bronchogenic cyst

PBC:

pulmonary bronchogenic cyst

References

  1. Haller JA, Shermeta DW, Donahoo JS (1975) Life-threatening respiratory distress from mediastinal masses in infants. Ann Thorac Surg 19:365–370

    PubMed  CAS  Google Scholar 

  2. Coselli MP, de Ipolyi P, Bloss RS, Diaz RF, Fitzgerald JB (1987) Bronchogenic cysts above and below the diaphragm: report of eight cases. Ann Thorac Surg 44:491–494

    Article  PubMed  CAS  Google Scholar 

  3. Lyerly HK, Sabiston DC Jr (1988) Primary neoplasms and cysts of the mediastinum. In: Fishman AP (ed) Pulmonary diseases and disorders, vol 3, 2nd edn. New York: McGraw-Hill, pp 2090–2091

    Google Scholar 

  4. Ko SF, Hsieh MJ, Linc JW, Huang CC, Li CC, Cheungd YC, Ng SH (2006) Bronchogenic cyst of the esophagus: clinical and imaging features of seven cases. Clin Imaging 30:309–314

    Article  PubMed  Google Scholar 

  5. Dogan R, Cetin G, Moldibi B, Kaya S, Alp M, Uçanok K, Unlu M (1988) Les kystes bronchogéniques pulmonaires et médiastinaux. Rev Mal Respir 5:123–127

    PubMed  CAS  Google Scholar 

  6. Aktogu S, Yuncu G, Halilcolar H, Ermete S, Buduneli T (1996) Bronchogenic cysts: Clinicopathological presentation and treatment. Eur Respir J 9:2017–2021

    Article  PubMed  CAS  Google Scholar 

  7. Ribet M, Copin M, Gosselin B (1995) Bronchogenic cysts of the mediastinum. J Thorac Cardiovasc Surg 109:1003–1010

    Article  PubMed  CAS  Google Scholar 

  8. Patel S, Meeker D, Biscotti C, Kirby T, Rice T (1994) Presentation and management of bronchogenic cysts in the adult. Chest 106:79–85

    Article  PubMed  CAS  Google Scholar 

  9. St. Georges R, Deslauriers J, Duranceau A, Vaillancourt R, Deschamps C, Beauchamp G, Pagé A, Brisson J (1991) Clinical spectrum of bronchogenic cysts of the mediastinum and lung in the adult. Ann Thorac Surg 52:6–13

    Article  PubMed  CAS  Google Scholar 

  10. Ferguson TB Jr, Ferguson TB (1995) Congenital lesions of the lung and emphysema. In: Sabiston DC Jr, Spencer FC (eds) Surgery of the chest, vol. 1, 6th edn. Philadelphia: W.B. Saunders, pp 857–860

    Google Scholar 

  11. Bolton J, Shalian D (1992) Asymptomatic bronchogenic cysts: what is the best management? Ann Thorac Surg 53:1134–1137

    Article  PubMed  CAS  Google Scholar 

  12. Suen HC, Mathisen DJ, Grillo HC, LeBlanc J, McLoud TC, Moncure AC, Hilgenberg AD (1993) Surgical management and radiological characteristics of bronchogenic cysts. Ann Thorac Surg 55:476–481

    Article  PubMed  CAS  Google Scholar 

  13. McAdams H, Kirejczyk WM, de Christenson ML, Matsumoto S (2000) Bronchogenic cyst: imaging features with clinical and histopathologic correlation. Radiology 217:441–446

    PubMed  CAS  Google Scholar 

  14. Hajjar W, El Madany Y, Ashour M, Al Kattan K (2003) Life threatening complications caused by bronchogenic cyst and oesophageal duplication cysts in a child. J Cardiovasc Surg 44:135–137

    CAS  Google Scholar 

  15. Wilson RL, Lettieri CJ, Fitzpatrik TM, Shorr AF (2005) Intralobular bronchopulmonary sequestrations associated with bronchogenic cysts. Respir Med 99:508–510

    Article  PubMed  Google Scholar 

  16. Smythe W, Bavaria J, Kaiser L (1998) Mediastinoscopic subtotal removal of mediastinal cysts. Chest 114:614–617

    Article  PubMed  CAS  Google Scholar 

  17. Rapado F, Bennett JD, Stringfellow JM (1998) Bronchogenic cyst: an unusual cause of lump in the neck. J Laryngol Otol 112:893–894

    PubMed  CAS  Google Scholar 

  18. Itoh H, Shitamura T, Kataoka H, Ide H, Akiyama Y, Hamasuna R, Hasui Y, Osada Y, Koono M (1999) Retroperitoneal bronchogenic cyst. Report of a case and literature review. Pathol Int 49:152

    Article  PubMed  CAS  Google Scholar 

  19. Pryce DM (1948) The lining of healed but persistent abscess cavities in the lung with epithelium of the ciliated columnar type. J Pathol Bacteriol 60:259–264

    Article  PubMed  CAS  Google Scholar 

  20. Metersky ML, Moskowitz H, Thayer JO (1995) Recurrent mediastinal bronchogenic cyst. Respiration 62:234–236

    Article  PubMed  CAS  Google Scholar 

  21. Gharagozloo F, Dausmann M, McReynolds S, Sanderson D, Helmers R (1995) Recurrent bronchogenic pseudocyst 24 years after incomplete excision: report of a case. Chest 108:880–883

    Article  PubMed  CAS  Google Scholar 

  22. Read C, Moront M, Carangelo R, Holt R, Richardson M (1991) Recurrent bronchogenic cyst. An argument for complete excision Arch Surg 126:1306–1308

    PubMed  CAS  Google Scholar 

  23. Rice DC, Putnam JB (2002) Recurrent bronchogenic cyst causing recurrent laryngeal nerve palsy. Eur J Cardiothorac Surg 21:561–563

    Article  PubMed  Google Scholar 

  24. Rammohan G, Berger HW, Lajam F, Buhain WJ (1975) Superior vena cava syndrome caused by bronchogenic cyst. Chest 68:599–601

    Article  PubMed  CAS  Google Scholar 

  25. Worsnop CJ, Teichtahl H, Clark CP (1993) Bronchogenic cyst a cause of pulmonary artery obstruction and breathlessness. Ann Thorac Surg 55:1254–1255

    Article  PubMed  CAS  Google Scholar 

  26. Watson A, Chandhary B (1987) Cardiac arrythmias and abnormal chest roentgenogram. Bronchogenic cyst. Chest 92:335–336

    CAS  Google Scholar 

  27. Endo C, Tadashi I, Hideyuki N, Akio E, Mitsumoi K (2000) Bronchioloalveolar carcinoma arising in a bronchogenic cyst. Ann Thorac Surg 69:933–935

    Article  PubMed  CAS  Google Scholar 

  28. Ashizawa K, Okimoto T, Shirafuji T, Kusano H, Ayabe H, Hayashi K (2001) Anterior mediastinal bronchogenic cyst: demonstration of complicating malignancy by CT and MRI. BrJ Radiol 74:959–961

    CAS  Google Scholar 

  29. Zaugg M, Kaplan V, Widmer U, Baumann P, Russi E (1998) Fatal air embolism in an airplane passenger with a giant intrapulmonary bronchogenic cyst. Am J Respir Crit Care Med 157:1686–1689

    PubMed  CAS  Google Scholar 

  30. Kennebeck G, Wong A, Berry W, Higgins J, Manubens S (1999) Mediastinal bronchogenic cyst manifesting as a catastrophic myocardial infarction. Ann Thorac Surg 67:1789–1791

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Faten Limaïem.

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Limaïem, F., Ayadi-Kaddour, A., Djilani, H. et al. Pulmonary and Mediastinal Bronchogenic Cysts: A Clinicopathologic Study of 33 Cases. Lung 186, 55–61 (2008). https://doi.org/10.1007/s00408-007-9056-4

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  • DOI: https://doi.org/10.1007/s00408-007-9056-4

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