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Evidence of H3 K27M mutations in posterior fossa ependymomas

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Authors and Affiliations

  1. DGNN Brain Tumor Reference Center, Institute of Neuropathology, University of Bonn Medical Center, 53105, Bonn, Germany

    Marco Gessi & Torsten Pietsch

  2. Department of Neuropathology, Institute of Pathology, Ruprecht-Karls-University Heidelberg, 69120, Heidelberg, Germany

    David Capper, Felix Sahm, Kristin Huang & Andreas von Deimling

  3. Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany

    David Capper, Felix Sahm, Kristin Huang & Andreas von Deimling

  4. HIT-REZ Study Center, Department of Pediatric Oncology and Hematology, Pediatrics III, University Hospital Essen, 45147, Essen, Germany

    Stephan Tippelt & Gudrun Fleischhack

  5. Department of Pediatric Oncology, University of Ulm, Children’s Hospital, 89075, Ulm, Germany

    Daniel Scherbaum

  6. Institute of Pathology Kaufbeuren, 87600, Kaufbeuren, Germany

    Joachim Alfer

  7. HIT-MED Study Center, Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany

    Björn-Ole Juhnke, Katja von Hoff & Stefan Rutkowski

  8. Department of Neuroradiology, German Reference Center for Neuroradiology, University Hospital of Würzburg, 97080, Würzburg, Germany

    Monika Warmuth-Metz

  9. Division of Pediatric Neurooncology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany

    Lukas Chavez, Stefan M. Pfister, David T. W. Jones & Dominik Sturm

  10. Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital, 69120, Heidelberg, Germany

    Stefan M. Pfister & Dominik Sturm

Authors
  1. Marco Gessi
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  2. David Capper
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  3. Felix Sahm
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  4. Kristin Huang
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  5. Andreas von Deimling
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  6. Stephan Tippelt
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  7. Gudrun Fleischhack
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  8. Daniel Scherbaum
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  9. Joachim Alfer
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  10. Björn-Ole Juhnke
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  11. Katja von Hoff
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  12. Stefan Rutkowski
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  13. Monika Warmuth-Metz
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  14. Lukas Chavez
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  15. Stefan M. Pfister
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  16. Torsten Pietsch
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  17. David T. W. Jones
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  18. Dominik Sturm
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Corresponding author

Correspondence to Dominik Sturm.

Electronic supplementary material

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401_2016_1608_MOESM1_ESM.pdf

Supplementary Fig. 1: Radiological appearance of H3F3A K27M- and HIST1H3C K27M-mutated ependymomas. Radiological appearance of case #1 in T1 (a), T1 with contrast enhancement (b), and T2 (c) sequences. Radiological appearance of case #2 in T1 with contrast enhancement (d) and T2 (e) sequences as well as the spinal metastasis in T1 with contrast enhancement (f) ( PDF 1951 kb)

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Gessi, M., Capper, D., Sahm, F. et al. Evidence of H3 K27M mutations in posterior fossa ependymomas. Acta Neuropathol 132, 635–637 (2016). https://doi.org/10.1007/s00401-016-1608-3

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  • DOI: https://doi.org/10.1007/s00401-016-1608-3

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