Abstract
A 58-year-old, otherwise healthy man presented with a sudden onset of watery diarrhea. A pseudomembranous colitis due to antibiotics was identified as the cause of the diarrhea. Enlargement of the spleen was detected during the evaluation. The enlarged, plump spleen (20 cm long, 7.1 cm wide) had multiple nodules that differed in size from 1 to 8 cm. Neither clinical nor other symptoms of an underlying malignant disease could be detected. Because the signs were of little diagnostic value we arranged a splenectomy, which showed a littoral cell angioma (LCA) to be the cause of splenomegaly. In addition to the case report, we have reviewed the literature, clinical manifestations, differential diagnosis, special gross and microscopic pathological findings, and the location of this benign vessel tumor in the pathology of the spleen.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received: 1 December 1999 / Accepted: 21 June 2000
Rights and permissions
About this article
Cite this article
Ziske, C., Meybehm, M., Sauerbruch, T. et al. Littoral cell angioma as a rare cause of splenomegaly. Ann Hematol 80, 45–48 (2001). https://doi.org/10.1007/s002770000223
Issue Date:
DOI: https://doi.org/10.1007/s002770000223