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Molecular analyses in the diagnosis of myeloproliferative neoplasm-related splanchnic vein thrombosis

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References

  1. Falanga A, Marchetti M (2012) Thrombotic disease in the myeloproliferative neoplasms. Hematol (Am Soc Hematol Educ Program) 2012:571–581

    Google Scholar 

  2. Martinelli I, De Stefano V, Carobbio A, Randi ML, Santarossa C, Rambaldi A et al (2014) Cerebral vein thrombosis in patients with Philadelphia-negative myeloproliferative neoplasms: an European Leukemia Net study. Am J Hematol 89:E200–205

    Article  PubMed  Google Scholar 

  3. Primignani M, Barosi G, Bergamaschi G, Gianelli U, Fabris F, Reati R et al (2006) Role of the JAK2 mutation in the diagnosis of chronic myeloproliferative disorders in splanchnic vein thrombosis. Hepatology 44:1528–1534

    Article  CAS  PubMed  Google Scholar 

  4. Sekhar M, McVinnie K, Burroughs AK (2013) Splanchnic vein thrombosis in myeloproliferative neoplasms. Br J Haematol 162:730–747

    Article  CAS  PubMed  Google Scholar 

  5. Kiladjian JJ, Cervantes F, Leebeek FW, Marzac C, Cassinat B, Chevret S, et al. (2008) The impact of JAK2 and MPL mutations on diagnosis and prognosis of splanchnic vein thrombosis: a report on 241 cases. Blood 111:4922–4929

  6. Smalberg JH, Arends LR, Valla DC, Kiladjian JJ, Janssen HL, Leebeek FW. (2012) Myeloproliferative neoplasms in Budd-Chiari syndrome and portal vein thrombosis: a meta-analysis. Blood 120:4921–4928

  7. Klampfl T, Gisslinger H, Harutyunyan AS, Nivarthi H, Rumi E, Milosevic JD, et al. (2013) Somatic mutations of calreticulin in myeloproliferative neoplasms. N Eng J Med 369:2379–2390

  8. Nangalia J, Massie CE, Baxter EJ, Nice FL, Gundem G, Wedge DC, et al. (2013) Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2. N Eng J Med 369:2391–2405

  9. Turon F, Cervantes F, Colomer D, Baiges A, Hernández-Gea V, Garcia-Pagán JC. (2014) Role of calreticulin mutations in the etiological diagnosis of splanchnic vein thrombosis. J Hepatol [Epub ahead of print]

  10. Haslam K, Langabeer SE. (2014) Incidence of CALR mutations in patients with splanchnic vein thrombosis. Br J Haematol [Epub ahead of print]

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Authorship

AI, DC and UG interpreted the data and prepared the manuscript. EF and CA performed laboratory studies. AC revised the data and approved the manuscript.

Conflict of interest

All authors disclose no conflicts of interest.

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Authors and Affiliations

  1. Oncohematology Division, IRCCS Ca’ Granda – Maggiore Policlinico Hospital Foundation and University of Milan, Milan, Italy

    Alessandra Iurlo, Daniele Cattaneo, Elisa Fermo & Agostino Cortelezzi

  2. Oncohematology Unit of the Elderly, IRCCS Ca’ Granda – Maggiore Policlinico Hospital Foundation and University of Milan, Milan, Italy

    Alessandra Iurlo

  3. Hematopathology Service, Division of Pathology, Department of Pathophysiology and Transplantation, University of Milan and IRCCS Ca’ Granda – Maggiore Policlinico Hospital Foundation, Milan, Italy

    Umberto Gianelli

  4. Division of Pathology, Department of Pathophysiology and Transplantation, University of Milan and IRCCS Ca’ Granda – Maggiore Policlinico Hospital Foundation, Milan, Italy

    Claudia Augello

  5. Oncohematology Division, Oncohematology Unit of the Elderly, Department of Clinical Sciences and Community, University of Milan Medical School and IRCCS Ca’ Granda – Maggiore Policlinico Hospital Foundation, Via F. Sforza 35, 20122, Milan, Italy

    Alessandra Iurlo

Authors
  1. Alessandra Iurlo
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  2. Daniele Cattaneo
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  3. Umberto Gianelli
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  4. Elisa Fermo
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  5. Claudia Augello
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  6. Agostino Cortelezzi
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Correspondence to Alessandra Iurlo.

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Iurlo, A., Cattaneo, D., Gianelli, U. et al. Molecular analyses in the diagnosis of myeloproliferative neoplasm-related splanchnic vein thrombosis. Ann Hematol 94, 881–882 (2015). https://doi.org/10.1007/s00277-014-2249-z

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  • DOI: https://doi.org/10.1007/s00277-014-2249-z

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