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Portal Vein Embolization: What Do We Know?

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Abstract

Portal vein embolization (PVE) has been developed to increase the size of the future remnant liver (FRL) left in place after major hepatectomy, thus reducing the risk of postoperative liver insufficiency. PVE consist in embolizing preoperatively portal branches of the segments that will be resected. Indication is based on preoperative measurements of the FRL by computed tomography and its ratio with either the theoretical liver volume or by direct measurement of the functional liver volume. After PVE, the volume and function of the FRL increases in 3 to 6 weeks, permitting extensive resections in patients otherwise contraindicated for liver resection. The PVE technique is variable from one center to another; however n-butyl-cyano-acrylate provides an interesting compromise between hypertrophy rate and procedure risk.

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References

  1. Vauthey JN, Baer HU, Guastella T et al (1993) Comparison of outcome between extended and nonextended liver resections for neoplasms: a multivariate analysis of prognostic factors. Surgery 114:968–975

    PubMed  CAS  Google Scholar 

  2. Takayasu K, Muramatsu Y, Shyma Y et al (1986) Hepatic lobar atrophy following obstruction of the ipsilateral portal vein from hilar cholangiocarcinoma. Radiology 160:389–393

    PubMed  CAS  Google Scholar 

  3. Kinoshita H, Sakai K, Hirohashi K et al (1986) Preoperative portal vein embolization for hepatocellular carcinoma. World J Surg 10:803–808

    Article  PubMed  CAS  Google Scholar 

  4. Rous P, Larimore L (1920) Relation of portal blood to liver maintenance. J Exp Med 31:609–632

    Article  PubMed  CAS  Google Scholar 

  5. Makuuchi M, Kosugue T, Lygidakis N (1991) New possibilities for major liver surgery in patients with Klatskin tumors or primary hepatocellular carcinoma—an old problem revisited. Hepatogastroenterology 38:329–336

    PubMed  CAS  Google Scholar 

  6. Makuushi M, Le Thai B, Takayasu K et al (1990) Preoperative portal embolization to increase safety of major hepatectomy for hilar bile duct carcinoma: a preliminary report. Surgery 107:521–527

    Google Scholar 

  7. de Baere T, Roche A, Vavasseur D et al (1993) Portal vein embolization: utility for inducing left hepatic lobe hypertrophy before surgery. Radiology 188:73–77

    PubMed  Google Scholar 

  8. Abdalla EK, Barnett CC, Doherty D et al (2002) Extended hepatectomy in patients with hepatobiliary malignancies with and without preoperative portal vein embolization. Arch Surg 137:675–680

    Article  PubMed  Google Scholar 

  9. Denys AL, Abehsera M, Leloutre B et al (2000) Intrahepatic hemodynamic changes following portal vein embolization: a prospective Doppler study. Eur Radiol 10:1703–1707

    Article  PubMed  CAS  Google Scholar 

  10. Harada H, Imamura H, Miyagawa S, Kawasaki S (1997) Fate of the human liver after hemihepatic portal vein embolization: cell kinetic and morphometric study. Hepatology 26:1162–1170

    PubMed  CAS  Google Scholar 

  11. Michalopoulos GK, De Frances MC (1997) Liver regeneration. Science 276(5309):60–66

    Article  PubMed  CAS  Google Scholar 

  12. Clavien PA, Petrowsky H, DeOliveira ML, Graf R (2007) Strategies for safer liver surgery and partial liver transplantation. N Engl J Med 356:1545–1559

    Article  PubMed  Google Scholar 

  13. Clavien PA (2008) Liver regeneration: a spotlight on the novel role of platelets and serotonin. Swiss Med Wkly 138:361–370

    PubMed  CAS  Google Scholar 

  14. Clavien PA, Graf R (2009) Liver regeneration and platelets. Br J Surg 96:965–966

    Article  PubMed  CAS  Google Scholar 

  15. Takamura K, Tsuchida K, Miyake H et al (2005) Activin and activin receptor expression changes in liver regeneration in rat. J Surg Res 126:3–11

    Article  PubMed  CAS  Google Scholar 

  16. Miyake H, Fujii M, Sasaki K et al (2003) Heat shock protein 70 induction in hepatocytes after right portal vein embolization. Hepatogastroenterology 50:2084–2087

    PubMed  CAS  Google Scholar 

  17. Oda H, Miyake H, Iwata T et al (2002) Geranylgeranylacetone suppresses inflammatory responses and improves survival after massive hepatectomy in rats. J Gastrointest Surg 6:464–472

    Article  PubMed  Google Scholar 

  18. Tanaka H, Hirohashi K, Kubo S et al (1999) Influence of histological inflammatory activity on regenerative capacity of liver after percutaneous transhepatic portal vein embolization. J Gastroenterol 34:100–104

    Article  PubMed  CAS  Google Scholar 

  19. de Baere T, Denys A, Paradis V (2009) Comparison of four embolic materials for portal vein embolization: experimental study in pigs. Eur Radiol 19:1435–1442

    Article  PubMed  Google Scholar 

  20. Zhou JY, Wong DW, Ding F et al (2010) Liver tumour segmentation using contrast-enhanced multi-detector CT data: performance benchmarking of three semiautomated methods. Eur Radiol 20:1738–1748

    Article  PubMed  Google Scholar 

  21. Azoulay D, Castaing D, Krissat J et al (2000) Percutaneous portal vein embolization increases the feasibility and safety of major liver resection for hepatocellular carcinoma in injured liver. Ann Surg 232:665–672

    Article  PubMed  CAS  Google Scholar 

  22. de Baere T, Denys A, Madoff DC (2007) Preoperative portal vein embolization: indications and technical considerations. Tech Vasc Interv Radiol 10:67–78

    Article  PubMed  Google Scholar 

  23. Denys A, Lacombe C, Schneider F et al (2005) Portal vein embolization with N-butyl cyanoacrylate before partial hepatectomy in patients with hepatocellular carcinoma and underlying cirrhosis or advanced fibrosis. J Vasc Interv Radiol 16:1667–1674

    Article  PubMed  Google Scholar 

  24. Vauthey JN, Abdalla EK, Doherty DA et al (2002) Body surface area and body weight predict total liver volume in Western adults. Liver Transpl 8:233–240

    Article  PubMed  Google Scholar 

  25. Shah A, Goffette P, Hubert C et al (2011) Comparison of different methods to quantify future liver remnants after preoperative portal vein embolization to predict postoperative liver failure. Hepatogastroenterology 58:109–114

    PubMed  Google Scholar 

  26. Vauthey JN, Chaoui A, Do KA et al (2000) Standardized measurement of the future liver remnant prior to extended liver resection: methodology and clinical associations. Surgery 127:512–519

    Article  PubMed  CAS  Google Scholar 

  27. Elias D, Ouellet JF, De Baere T et al (2002) Preoperative selective portal vein embolization before hepatectomy for liver metastases: long-term results and impact on survival. Surgery 131:294–299

    Article  PubMed  Google Scholar 

  28. Imamura H, Sano K, Sugawara Y et al (2005) Assessment of hepatic reserve for indication of hepatic resection: decision tree incorporating indocyanine green test. J Hepatobiliary Pancreat Surg 12:16–22

    Article  PubMed  Google Scholar 

  29. Bruix J, Castells A, Bosch J et al (1996) Surgical resection of hepatocellular carcinoma in cirrhotic patients: prognostic value of preoperative portal pressure. Gastroenterology 111:1018–1022

    Article  PubMed  CAS  Google Scholar 

  30. Poon RT, Fan ST (2005) Assessment of hepatic reserve for indication of hepatic resection: how I do it. J Hepatobiliary Pancreat Surg 12:31–37

    Article  PubMed  Google Scholar 

  31. Abdalla EK (2010) Portal vein embolization (prior to major hepatectomy) effects on regeneration, resectability, and outcome. J Surg Oncol 102:960–967

    Article  PubMed  Google Scholar 

  32. Farges O, Malassagne B, Flejou JF et al (1999) Risk of major liver resection in patients with underlying chronic liver disease: a reappraisal. Ann Surg 229:210–215

    Article  PubMed  CAS  Google Scholar 

  33. Farges O, Belghiti J, Kianmanesh R et al (2003) Portal vein embolization before right hepatectomy: prospective clinical trial. Ann Surg 237:208–217

    PubMed  Google Scholar 

  34. de Baere T, Teriitehau C, Deschamps F et al (2010) Predictive factors for hypertrophy of the future remnant liver after selective portal vein embolization. Ann Surg Oncol 17:2081–2089

    Article  PubMed  Google Scholar 

  35. de Graaf W, Bennink RJ, Vetelainen R, van Gulik TM (2010) Nuclear imaging techniques for the assessment of hepatic function in liver surgery and transplantation. J Nucl Med 51:742–752

    Article  PubMed  Google Scholar 

  36. Vera DR, Krohn KA, Stadalnik RC, Scheibe PO (1984) Tc-99 m-galactosyl-neoglycoalbumin: in vivo characterization of receptor-mediated binding to hepatocytes. Radiology 151:191–196

    PubMed  CAS  Google Scholar 

  37. Kwon AH, Ha-Kawa SK, Uetsuji S et al (1997) Preoperative determination of the surgical procedure for hepatectomy using technetium-99 m-galactosyl human serum albumin (99mTc-GSA) liver scintigraphy. Hepatology 25:426–429

    Article  PubMed  CAS  Google Scholar 

  38. Nanashima A, Yamaguchi H, Shibasaki S et al (2004) Relationship between indocyanine green test and technetium-99 m galactosyl serum albumin scintigraphy in patients scheduled for hepatectomy: clinical evaluation and patient outcome. Hepatol Res 28:184–190

    Article  PubMed  Google Scholar 

  39. Hirai I, Kimura W, Fuse A et al (2003) Evaluation of preoperative portal embolization for safe hepatectomy, with special reference to assessment of nonembolized lobe function with 99 mTc-GSA SPECT scintigraphy. Surgery 133:495–506

    Article  PubMed  Google Scholar 

  40. Nanashima A, Tobinaga S, Abo T et al (2010) Relationship of hepatic functional parameters with changes of functional liver volume using technetium-99 m galactosyl serum albumin scintigraphy in patients undergoing preoperative portal vein embolization: a follow-up report. J Surg Res 164:e235–e242

    Article  PubMed  Google Scholar 

  41. Nishiyama Y, Yamamoto Y, Hino I et al (2003) 99mTc galactosyl human serum albumin liver dynamic SPET for pre-operative assessment of hepatectomy in relation to percutaneous transhepatic portal embolization. Nucl Med Commun 24:809–817

    Article  PubMed  CAS  Google Scholar 

  42. Yumoto Y, Yagi T, Sato S et al (2010) Preoperative estimation of remnant hepatic function using fusion images obtained by (99m)Tc-labelled galactosyl-human serum albumin liver scintigraphy and computed tomography. Br J Surg 97:934–944

    Article  PubMed  CAS  Google Scholar 

  43. Krishnamurthy GT, Krishnamurthy S (2006) Cholescintigraphic measurement of liver function: how is it different from other methods? Eur J Nucl Med Mol Imaging 33:1103–1106

    Article  PubMed  Google Scholar 

  44. Heyman S (1994) Hepatobiliary scintigraphy as a liver function test. J Nucl Med 35:436–437

    PubMed  CAS  Google Scholar 

  45. de Graaf W, van Lienden KP, van Gulik TM, Bennink RJ (2010) (99m)Tc-mebrofenin hepatobiliary scintigraphy with SPECT for the assessment of hepatic function and liver functional volume before partial hepatectomy. J Nucl Med 51:229–236

    Article  PubMed  Google Scholar 

  46. Bennink RJ, Dinant S, Erdogan D et al (2004) Preoperative assessment of postoperative remnant liver function using hepatobiliary scintigraphy. J Nucl Med 45:965–971

    PubMed  Google Scholar 

  47. van den Esschert JW, de Graaf W, van Lienden KP et al (2009) Volumetric and functional recovery of the remnant liver after major liver resection with prior portal vein embolization : recovery after PVE and liver resection. J Gastrointest Surg 13:1464–1469

    Article  PubMed  Google Scholar 

  48. Erdogan D, Heijnen BH, Bennink RJ et al (2004) Preoperative assessment of liver function: a comparison of 99mTc-Mebrofenin scintigraphy with indocyanine green clearance test. Liver Int 24:117–123

    Article  PubMed  CAS  Google Scholar 

  49. Dinant S, de Graaf W, Verwer BJ et al (2007) Risk assessment of posthepatectomy liver failure using hepatobiliary scintigraphy and CT volumetry. J Nucl Med 48:685–692

    Article  PubMed  Google Scholar 

  50. de Graaf W, van Lienden KP, van den Esschert JW et al (2011) Increase in future remnant liver function after preoperative portal vein embolization. Br J Surg 98:825–834

    Article  PubMed  Google Scholar 

  51. Bennink RJ, de Graaf W, van Gulik TM (2011) Toward a total and regional scintigraphic liver function test enabling assessment of future remnant liver function. Nucl Med Commun 32:669–671

    Article  PubMed  Google Scholar 

  52. Madoff DC, Abdalla EK, Vauthey JN (2005) Portal vein embolization in preparation for major hepatic resection: evolution of a new standard of care. J Vasc Interv Radiol 16:779–790

    Article  PubMed  Google Scholar 

  53. De Baere T, Roche A, Elias D et al (1996) Preoperative portal vein embolization for extension of hepatectomy indications. Hepatology 24:1386–1391

    Article  PubMed  Google Scholar 

  54. Bent CL, Low D, Matson MB et al (2009) Portal vein embolization using a nitinol plug (Amplatzer vascular plug) in combination with histoacryl glue and iodinized oil: adequate hypertrophy with a reduced risk of nontarget embolization. Cardiovasc Intervent Radiol 32:471–477

    Article  PubMed  Google Scholar 

  55. Di Stefano DR, de Baere T, Denys A et al (2005) Preoperative percutaneous portal vein embolization: evaluation of adverse events in 188 patients. Radiology 234:625–630

    Article  PubMed  Google Scholar 

  56. Kodama Y, Shimizu T, Endo H et al (2002) Complications of percutaneous transhepatic portal vein embolization. J Vasc Interv Radiol 13:1233–1237

    Article  PubMed  Google Scholar 

  57. Madoff DC, Hicks ME, Vauthey JN et al (2002) Transhepatic portal vein embolization: anatomy, indications, and technical considerations. Radiographics 22:1063–1076

    PubMed  Google Scholar 

  58. Covey AM, Tuorto S, Brody LA et al (2005) Safety and efficacy of preoperative portal vein embolization with polyvinyl alcohol in 58 patients with liver metastases. AJR Am J Roentgenol 185:1620–1626

    Article  PubMed  Google Scholar 

  59. Madoff DC, Hicks ME, Abdalla EK et al (2003) Portal vein embolization with polyvinyl alcohol particles and coils in preparation for major liver resection for hepatobiliary malignancy: safety and effectiveness–study in 26 patients. Radiology 227:251–260

    Article  PubMed  Google Scholar 

  60. Ogasawara K, Uchino J, Une Y, Fujioka Y (1996) Selective portal vein embolization with absolute ethanol induces hepatic hypertrophy and makes more extensive hepatectomy possible. Hepatology 23:338–345

    Article  PubMed  CAS  Google Scholar 

  61. Denys A, Bize P, Demartines N et al (2010) Quality improvement for portal vein embolization. Cardiovasc Intervent Radiol 33:452–456

    Article  PubMed  Google Scholar 

  62. Madoff DC, Abdalla EK, Gupta S et al (2005) Transhepatic ipsilateral right portal vein embolization extended to segment IV: improving hypertrophy and resection outcomes with spherical particles and coils. J Vasc Interv Radiol 16(21):215–225

    Article  PubMed  Google Scholar 

  63. Aussilhou B, Lesurtel M, Sauvanet A et al (2008) Right portal vein ligation is as efficient as portal vein embolization to induce hypertrophy of the left liver remnant. J Gastrointest Surg 12:297–303

    Article  PubMed  CAS  Google Scholar 

  64. Kianmanesh R, Farges O, Abdalla EK et al (2003) Right portal vein ligation: a new planned two-step all-surgical approach for complete resection of primary gastrointestinal tumors with multiple bilateral liver metastases. J Am Coll Surg 197:164–170

    Article  PubMed  Google Scholar 

  65. Jaeck D, Bachellier P, Nakano H et al (2003) One or two-stage hepatectomy combined with portal vein embolization for initially nonresectable colorectal liver metastases. Am J Surg 185:221–229

    Article  PubMed  Google Scholar 

  66. Denys AL, Abehsera M, Sauvanet A et al (1999) Failure of right portal vein ligation to induce left lobe hypertrophy due to intrahepatic portoportal collaterals: successful treatment with portal vein embolization. AJR Am J Roentgenol 173:633–635

    PubMed  CAS  Google Scholar 

  67. Elias D, Santoro R, Ouellet JF et al (2004) Simultaneous percutaneous right portal vein embolization and left liver tumor radiofrequency ablation prior to a major right hepatic resection for bilateral colorectal metastases. Hepatogastroenterology 51:1788–1791

    PubMed  Google Scholar 

  68. Furrer K, Tian Y, Pfammatter T et al (2008) Selective portal vein embolization and ligation trigger different regenerative responses in the rat liver. Hepatology 47:1615–1623

    Article  PubMed  Google Scholar 

  69. van den Esschert JW, van Lienden KP, de Graaf W et al (2011) Portal vein embolization induces more liver regeneration than portal vein ligation in a standardized rabbit model. Surgery 149:378–385

    Article  PubMed  Google Scholar 

  70. Wilms C, Mueller L, Lenk C et al (2008) Comparative study of portal vein embolization versus portal vein ligation for induction of hypertrophy of the future liver remnant using a mini-pig model. Ann Surg 247:825–834

    Article  PubMed  Google Scholar 

  71. Abdalla EK, Denys A, Chevalier P et al (2004) Total and segmental liver volume variations: implications for liver surgery. Surgery 135:404–410

    Article  PubMed  Google Scholar 

  72. Kishi Y, Madoff DC, Abdalla EK et al (2008) Is embolization of segment 4 portal veins before extended right hepatectomy justified? Surgery 144:744–751

    Article  PubMed  Google Scholar 

  73. Ribero D, Abdalla EK, Madoff DC et al (2007) Portal vein embolization before major hepatectomy and its effects on regeneration, resectability and outcome. Br J Surg 94:1386–1394

    Article  PubMed  CAS  Google Scholar 

  74. Fujii Y, Shimada H, Endo I et al (2003) Risk factors of posthepatectomy liver failure after portal vein embolization. J Hepatobiliary Pancreat Surg 10:226–232

    Article  PubMed  Google Scholar 

  75. Correa D, Schwartz L, Jarnagin WR et al (2010) Kinetics of liver volume changes in the first year after portal vein embolization. Arch Surg 145:351–354

    Article  PubMed  Google Scholar 

  76. Covey AM, Brown KT, Jarnagin WR et al (2008) Combined portal vein embolization and neoadjuvant chemotherapy as a treatment strategy for resectable hepatic colorectal metastases. Ann Surg 247:451–455

    Article  PubMed  Google Scholar 

  77. Rubbia-Brandt L, Mentha G, Terris B (2006) Sinusoidal obstruction syndrome is a major feature of hepatic lesions associated with oxaliplatin neoadjuvant chemotherapy for liver colorectal metastases. J Am Coll Surg 202:199–200

    Article  PubMed  Google Scholar 

  78. van Gulik TM, van den Esschert JW, de Graaf W et al (2008) Controversies in the use of portal vein embolization. Dig Surg 25:436–444

    Article  PubMed  Google Scholar 

  79. Broering DC, Hillert C, Krupski G et al (2002) Portal vein embolization vs. portal vein ligation for induction of hypertrophy of the future liver remnant. J Gastrointest Surg 6:905–913

    Article  PubMed  Google Scholar 

  80. Hwang S, Lee SG, Ko GY et al (2009) Sequential preoperative ipsilateral hepatic vein embolization after portal vein embolization to induce further liver regeneration in patients with hepatobiliary malignancy. Ann Surg 249:608–616

    Article  PubMed  Google Scholar 

  81. Kishi Y, Abdalla EK, Chun YS et al (2009) Three hundred and one consecutive extended right hepatectomies: evaluation of outcome based on systematic liver volumetry. Ann Surg 250:540–548

    PubMed  Google Scholar 

  82. Okano T, Ohwada S, Nakasone Y et al (2001) Blood transfusion causes deterioration in liver regeneration after partial hepatectomy in rats. J Surg Res 101:157–165

    Article  PubMed  CAS  Google Scholar 

  83. Halazun KJ, Al-Mukhtar A, Aldouri A et al (2007) Right hepatic trisectionectomy for hepatobiliary diseases: results and an appraisal of its current role. Ann Surg 246:1065–1074

    Article  PubMed  Google Scholar 

  84. Okabe H, Beppu T, Ishiko T et al (2011) Preoperative portal vein embolization (PVE) for patients with hepatocellular carcinoma can improve resectability and may improve disease-free survival. J Surg Oncol 104:641–646

    Article  PubMed  Google Scholar 

  85. Palavecino M, Chun YS, Madoff DC et al (2009) Major hepatic resection for hepatocellular carcinoma with or without portal vein embolization: perioperative outcome and survival. Surgery 145:399–405

    Article  PubMed  Google Scholar 

  86. Yoo H, Ko GY, Gwon DI et al (2009) Preoperative portal vein embolization using an amplatzer vascular plug. Eur Radiol 19:1054–1061

    Article  PubMed  Google Scholar 

  87. Yokoyama Y, Nagino M, Oda K et al (2008) Sex dimorphism in the outcome of preoperative right portal vein embolization. Arch Surg 143:254–259

    Article  PubMed  Google Scholar 

  88. Giraudo G, Greget M, Oussoultzoglou E et al (2008) Preoperative contralateral portal vein embolization before major hepatic resection is a safe and efficient procedure: a large single institution experience. Surgery 143:476–482

    Article  PubMed  Google Scholar 

  89. Sugawara Y, Yamamoto J, Higashi H et al (2002) Preoperative portal embolization in patients with hepatocellular carcinoma. World J Surg 26:105–110

    Article  PubMed  Google Scholar 

  90. Wakabayashi H, Ishimura K, Okano K et al (2002) Application of preoperative portal vein embolization before major hepatic resection in patients with normal or abnormal liver parenchyma. Surgery 131:26–33

    Article  PubMed  Google Scholar 

  91. Azoulay D, Castaing D, Smail A et al (2000) Resection of nonresectable liver metastases from colorectal cancer after percutaneous portal vein embolization. Ann Surg 231:480–486

    Article  PubMed  CAS  Google Scholar 

  92. Imamura H, Shimada R, Kubota M et al (1999) Preoperative portal vein embolization: an audit of 84 patients. Hepatology 29:1099–1105

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Radiology and Interventional Radiology Unit, Centre Hospitalo Universitaire Vaudois, 41 rue du Bugnon, 1011, Lausanne, Switzerland

    Alban Denys, Pierre Bize & Rafael Duran

  2. Department of Nuclear Medicine, Centre Hospitalo Universitaire Vaudois, 41 rue du Bugnon, 1011, Lausanne, Switzerland

    John Prior

  3. Department of Interventional Radiology, Institut Gustave Roussy, Pavillon de Recherche 1, 94805, Villejuif, France

    Thierry De Baere

  4. Department of Visceral Surgery, Centre Hospitalo Universitaire Vaudois, 41 rue du Bugnon, 1011, Lausanne, Switzerland

    Nermin Halkic & Nicolas Demartines

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  1. Alban Denys
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  3. Pierre Bize
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Denys, A., Prior, J., Bize, P. et al. Portal Vein Embolization: What Do We Know?. Cardiovasc Intervent Radiol 35, 999–1008 (2012). https://doi.org/10.1007/s00270-011-0300-1

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