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Extended abdominopelvic MRI versus CT at the time of adnexal mass characterization for assessing radiologic peritoneal cancer index (PCI) prior to cytoreductive surgery

  • Peritoneum
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Abstract

Purpose

To evaluate whether extending the MRI scan to include the abdomen at the time of adnexal mass characterization could replace additional CT for peritoneal cancer index (PCI) assessment.

Methods

After institutional review board approval for this prospective study, 36 consecutive females with ovarian and FT malignancies were included. All patients signed an informed consent. Patients underwent preoperative CT (32 patients) and MRI (36 patients). Images were interpreted by 2 independent observers. Surgical data were available in 27 patients. Region-by-region analysis was performed for detection rates of peritoneal carcinomatosis (PC). Inter-observer agreement for each region was evaluated by kappa statistics. Radiologic PCI was calculated by CT and MRI independently and inter-observer agreement for CT and MRI as well as agreement between radiologic and surgical PCI were evaluated by weighted-kappa statistics.

Results

On region-by-region analysis, the highest detection rates of PC were noted at the central abdomen and pelvis. Detection rates were higher by MRI than CT, mainly in bowel serosal surface, pelvis, and right upper abdomen regions. Inter-observer agreement of MRI was higher than CT in most regions. The median PCI by CT was 5 and 4 for the first and second observers (range 0–21 for both observers), respectively. The median PCI by MRI was 6 (range 0–23 for both observers). The inter-observer agreement of PCI was excellent by both CT and MRI (k = 0.876 and k = 0.912, respectively). The agreement between CT and surgical PCI was 0.660 and 0.590 for the first and second observers, respectively. The agreement between MRI and surgical PCI was 0.797 and 0.798 for the first and second observers, respectively.

Conclusions

Extending MRI scan to include the abdomen at the time of adnexal mass characterization allows accurate estimation of PC, with better results than CT, obviating the need for dedicated CT scan of abdomen and pelvis for imaging of PC.

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Funding

This work received no funding or grants.

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Authors and Affiliations

  1. Faculty of Medicine, Department of Diagnostic and Interventional Radiology, Mansoura University, 12 El-Gomhoreya Street, Mansoura, 35112, Egypt

    Basma Gadelhak, Ahmed M. Tawfik, Gehad A. Saleh, Nihal M. Batouty & Donia M. Sobh

  2. Department of Surgical Oncology, Oncology Center Mansoura University, Mansoura, Egypt

    Omar Hamdy & Basel Refky

Authors
  1. Basma Gadelhak
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  2. Ahmed M. Tawfik
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  3. Gehad A. Saleh
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  4. Nihal M. Batouty
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  5. Donia M. Sobh
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  6. Omar Hamdy
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  7. Basel Refky
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Correspondence to Ahmed M. Tawfik.

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Gadelhak, B., Tawfik, A.M., Saleh, G.A. et al. Extended abdominopelvic MRI versus CT at the time of adnexal mass characterization for assessing radiologic peritoneal cancer index (PCI) prior to cytoreductive surgery. Abdom Radiol 44, 2254–2261 (2019). https://doi.org/10.1007/s00261-019-01939-y

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  • DOI: https://doi.org/10.1007/s00261-019-01939-y

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