Skip to main content
SpringerLink
Log in

Activity of Crohn disease: value of Color-Power-Doppler and contrast-enhanced ultrasonography

  • Published:
Abdominal Imaging Aims and scope Submit manuscript

Abstract

Diagnosis and follow-up of Crohn disease (CD) often require invasive instrumental examinations, with a high risk of iatrogenic damage. Ultrasound (US) examination of bowel walls could be the first choice in managing patients with CD. We evaluated the role of tissue color power Doppler (CPD) and B-mode US with intravenous injection of contrast medium in the detection of disease activity. In our series, 52 patients with CD underwent US examination. Each study was completed with tissue CPD and US with intravenous injection of contrast medium (Sono Vue) to evaluate intestinal wall vascularization as an index of disease activity. We then compared our results with those from clinical and laboratory tests and follow-up. Data from US examination with intravenous injection of Sono Vue partly agreed with clinical and laboratory tests and CPD in disease activity evaluation but were most useful in the follow-up. Bowel US examination associated with CPD and in particular US contrast medium injection can be used to detect CD activity and modulate therapy and follow-up.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1
Figure 2
Figure 3

Similar content being viewed by others

References

  1. F Shanan (2002) ArticleTitleCrohn’s disease. Lancet 359 62–69 Occurrence Handle10.1016/S0140-6736(02)07284-7 Occurrence Handle11809204

    Article  PubMed  Google Scholar 

  2. G Di Candio F Mosca A Campatelli et al. (1986) ArticleTitleSonographic detection of postsurgical recurrence of Crohn’s disease. AJR 146 523–526 Occurrence Handle1:STN:280:BimC38not1c%3D Occurrence Handle3511636

    CAS  PubMed  Google Scholar 

  3. MB Sheridan DA Nicholson DF Martin (1993) ArticleTitleTransabdominal ultrasonography as the primary investigation in patients with suspected Crohn’s disease or recurrence: a prospective study. Clin Radiol 48 402–404 Occurrence Handle1:STN:280:ByuC38zltlA%3D Occurrence Handle8293646

    CAS  PubMed  Google Scholar 

  4. T Bozkurt F Richhter G Lux (1994) ArticleTitleUltrasonography as primary diagnostic tool in patients with inflammatory disease and tumors of the small intestine and large bowel. J Clin Ultrasound 22 85–91 Occurrence Handle1:STN:280:ByuC2sbltFI%3D Occurrence Handle8132801

    CAS  PubMed  Google Scholar 

  5. G Maconi F Parente S Bollani et al. (1996) ArticleTitleAbdominal ultrasound in the assessment of extent and activity of Crohn’s disease: clinical significance and implication of bowel wall thickening. Am J Gastroenterol 91 1604–1609 Occurrence Handle1:STN:280:BymA383hvVQ%3D Occurrence Handle8759670

    CAS  PubMed  Google Scholar 

  6. A Sonnenberg J Erckenbrecht P Peter et al. (1982) ArticleTitleDetection of Crohn disease at ultrasound. Gastroenterology 83 430–434 Occurrence Handle1:STN:280:Bi2B3M7msVw%3D Occurrence Handle7084620

    CAS  PubMed  Google Scholar 

  7. H Worlicek H Lutz H Heyder et al. (1987) ArticleTitleUltrasound findings in Crohn’s disease and ulcerative colitis: a prospective study. J Clin Ultrasound 15 153–163 Occurrence Handle1:STN:280:BieB2szmtlc%3D Occurrence Handle3134409

    CAS  PubMed  Google Scholar 

  8. WB Schwerk K Beckh M Raith (1992) ArticleTitleA prospective evaluation of high resolution sonography in the diagnosis of inflammatory bowel disease. Eur J Gastroenterol Hepatol 4 173–182

    Google Scholar 

  9. a Kohn P Cerro G Milite et al. (1999) ArticleTitleProspective evaluation of transabdominal bowel sonography in the diagnosis of intestinal obstruction in Crohn’s disease: comparison with plain abdominal film and small bowel enteroclysis. Inflamm Bowel Dis 5 153–157 Occurrence Handle1:STN:280:DyaK1Mzot1Onsw%3D%3D Occurrence Handle10453369

    CAS  PubMed  Google Scholar 

  10. G Maconi F Parente S Bollani et al. (1998) ArticleTitleFactors affecting splanchnic haemodynamics in Crohn’s disease: a prospective controlled study using Doppler ultrasound. Gut 43 645–650 Occurrence Handle1:STN:280:DyaK1M%2FntFamsw%3D%3D Occurrence Handle9824345

    CAS  PubMed  Google Scholar 

  11. F Brahme C Lindstrome (1970) ArticleTitleA comparative radiographic and pathological study of intestinal vasoarchitecture in Crohn’s disease and ulcerative colitis. Gut 11 928–940 Occurrence Handle1:STN:280:CS6D2sjps1Q%3D Occurrence Handle5492249

    CAS  PubMed  Google Scholar 

  12. F Calliada R Campani O Bottinelli et al. (1998) ArticleTitleUltrasound contrast agents. Basic principles. Eur J Radiol 27 S157–S160 Occurrence Handle10.1016/S0720-048X(98)00057-6 Occurrence Handle9652516

    Article  PubMed  Google Scholar 

  13. JM Correas L Bridal A Lesavre et al. (2001) ArticleTitleUltrasound contrast agent: properties, principles of action, tolerance and artifact. Eur Radiol 11 1316–1328 Occurrence Handle10.1007/s003300100940 Occurrence Handle1:STN:280:DC%2BD3Mvns1ajtQ%3D%3D Occurrence Handle11519538

    Article  CAS  PubMed  Google Scholar 

  14. CJ Harvey MJK Blomley RJ Eckersley DO Cosgrove (2001) ArticleTitleDevelopment in ultrasound contrast media. Eur Radiol 11 675–689 Occurrence Handle10.1007/s003300000624 Occurrence Handle1:STN:280:DC%2BD3M3lsFelsA%3D%3D Occurrence Handle11354767

    Article  CAS  PubMed  Google Scholar 

  15. T Ochsenkuhn M Sackmann B Goke (2003) ArticleTitleinflammatory bowel disease (IBD): critical discussion of etiology, pathogenesis, diagnostic and therapy. Radiologe 43 1–8 Occurrence Handle10.1007/s00117-002-0844-9 Occurrence Handle1:STN:280:DC%2BD3s%2Fktlaisg%3D%3D Occurrence Handle12552369

    Article  CAS  PubMed  Google Scholar 

  16. A Pera T Cammarota E Comino et al. (1988) ArticleTitleUltrasonography in the detection of Crohn’s disease and in the differential diagnosis of IBD. Digestion 41 180–184 Occurrence Handle1:STN:280:BiaC3sjotVw%3D Occurrence Handle3066675

    CAS  PubMed  Google Scholar 

  17. MB Sheridan DA Nicholson DF Martin (1993) ArticleTitleTransabdominal ultrasonography as the primary investigation in patients with suspected Crohn’s disease or recurrence: a prospective study. Clin Radiol 48 402–404 Occurrence Handle1:STN:280:ByuC38zltlA%3D Occurrence Handle8293646

    CAS  PubMed  Google Scholar 

  18. T Cammarota F Bresso A Sarno et al. (2000) ArticleTitleDolore addominale e alterazioni dell’alvo. Ruolo diagnostico dell’ecotomografia. Radiol Med 100 337–342 Occurrence Handle1:STN:280:DC%2BD3M7ktF2isA%3D%3D

    CAS  Google Scholar 

  19. F Parente G Maconi G Bianchi Porro (2002) ArticleTitleBowel ultrasound in Crohn disease: current role and future applications. Scand J Gastroenterol 37 871–876 Occurrence Handle10.1080/003655202760230801 Occurrence Handle1:STN:280:DC%2BD38vmvFyitw%3D%3D Occurrence Handle12229959

    Article  CAS  PubMed  Google Scholar 

  20. M Schneider (1999) ArticleTitleSono Vue, a new ultrasound contrast agent. Eur Radiol 9 IssueIDsuppl 3 347–348 Occurrence Handle10.1007/s003300050660 Occurrence Handle10101661

    Article  PubMed  Google Scholar 

  21. D Bokor (2000) ArticleTitleDiagnostic efficacy of Sono Vue. Am J Cardiol 17 IssueIDsuppl 4A 19G–24G Occurrence Handle10.1016/S0002-9149(00)00985-1

    Article  Google Scholar 

  22. PN Burns JE Power T Fritzsch (1992) ArticleTitleHarmonic imaging and Doppler method for contrast-enhanced ultrasound. Radiology 185 142

    Google Scholar 

  23. PN Burns (1996) ArticleTitleHarmonic imaging with ultrasound contrast agents. Clin Radiol 51 50–55

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology, San Giovanni Battista Hospital, Via Cherasco 23, 10126 Torino, Italy

    D. Robotti, T. Cammarota, P. Debani & A. Sarno

  2. Department of Gastroenterology, San Giovanni Battista Hospital, Via Cherasco 23, 10126 Torino, Italy

    M. Astegiano

Authors
  1. D. Robotti
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. T. Cammarota
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. P. Debani
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. Sarno
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. M. Astegiano
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Robotti, D., Cammarota, T., Debani, P. et al. Activity of Crohn disease: value of Color-Power-Doppler and contrast-enhanced ultrasonography . Abdom Imaging 29, 648–652 (2004). https://doi.org/10.1007/s00261-003-0157-0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00261-003-0157-0

Keywords

Search

Navigation