Skip to main content
Log in

Gross vertebral collapse associated with long-term disodium etidronate treatment for pelvic Paget’s disease

  • Case Report
  • Published:
Skeletal Radiology Aims and scope Submit manuscript

Abstract 

Inhibition of skeletal mineralisation is a well-recognized complication of disodium etidronate therapy that was identified in the earliest studies of its use in osteoporosis and Paget’s disease. The effect is seen at lower doses in Paget’s disease than in osteoporosis. Several cases of spontaneous fractures occurring in unaffected bones of Paget’s patients have been reported. However, we believe the case described here is the most severe example of etidronate-induced osteomalacia published in the literature, featuring widespread vertebral collapse occurring as a consequence of nearly 10 years of uninterrupted etidronate treatment for isolated hemipelvic Paget’s disease.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Author information

Authors and Affiliations

Authors

Additional information

Received: 9 August 1999 Revision requested: 19 October 1999 Revision received: 6 December 1999 Accepted: 8 December 1999

Rights and permissions

Reprints and permissions

About this article

Cite this article

MacGowan, J., Pringle, J., Morris, V. et al. Gross vertebral collapse associated with long-term disodium etidronate treatment for pelvic Paget’s disease. Skeletal Radiol 29, 279–282 (2000). https://doi.org/10.1007/s002560050608

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s002560050608

Navigation